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ImmunoEpigenetics65. 7-keto-cholesterol-induced miR-144 transcription inhibits IDH2 translation lowering NADPH required for NO synthesis to maintain endothelial function leading to atherosclerosis.

Authentic Biochemistry

English - May 14, 2023 17:23 - 30 minutes - 27.8 MB - ★★★★★ - 10 ratings
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Previous Episode: ImmunoEpigenetics64. IDH1/2 ad Malic enzymes 1/2/3 may generate NADPH thus driving removal of ROS while simultaneously promoting atherosclerosis and tumorigenesis via epigenetic and bioenergetic means

Next Episode: ImmunoEpigenetics 66. The NOX/PHOX/DUOX enzymes in atherosclerosis, thyroid hormonogenesis and thyroid tumorigenesis. An epigenetic telos from oxidized lipid to altered transcription patterns.DJGPhD.

References

Free Radical Biology and Medicine
Volume 71, June. Pages 1-15
Cardiovasc.Res. 2012 May 1; 94(2): 379–390.

Int. J. Mol. Sci. 2020, 21(7), 2578; https://doi.org/10.3390/ijms21072578

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