For teens and young adults with cancer or multiple sclerosis, navigating these diseases in the prime of their life is a lonely endeavor. Ryan O’Donoghue is on a mission to create impact through life-changing outdoor adventures.

“That rock doesn’t care that you have cancer; those rapids aren’t going to mellow out. They’re not treating you any differently.”

After losing his brother, Colin, to cancer at age 28, Ryan founded Rise Above It, an organization committed to advancing the field of adolescent and young adult oncology. Now, he serves as CEO for both First Descents and their for-profit subsidiary, Stoke Broker

Through each of these companies, and with a Zero Excuses mentality, Ryan is helping young adults with serious health conditions overcome their perceived limitations and regain their self-confidence.