LSU Tigers vs Florida Gators betting picks, predictions and odds for their SEC Football showdown on Saturday, October 16 2021 at 12:00pm ET from Tiger Stadium in Baton Rouge, Louisiana. LSU has covered the spread in three of the last four meetings with the Gators, including an outright win as a 23-point underdog last season. Direct from Las Vegas, our panel of professional sports handicappers look at the Vegas odds and offer their expert college football analysis on this clash between the Gators and Tigers. At the time of posting, the WagerTalk Live Odds screen is showing Florida as a -10.5 road favorite at LSU, with the over/under sitting at 58.5 points.