Iowa Hawkeyes vs Penn State Nittany Lions betting picks, predictions and odds for their Big Ten Football showdown on Saturday, October 9 2021 at 4:00pm ET from Kinnick Stadium in Iowa City, Iowa. Direct from Las Vegas, our panel of professional sports handicappers look at the Vegas odds and offer their expert college football analysis on this College Football Week 6 clash between the Hawkeyes and Nittany Lions. At the time of posting, the WagerTalk Live Odds screen is showing Iowa as a 2-point home favorite over Penn State, with the over/under sitting at 41.5 points.