Around 40% of adults will experience acid reflux at some point in their lives, and half of them will take medication to control consistent recurrences, known as gastroesophageal reflux disease, or GERD. It is important to diagnose patients with GERD to help them avoid esophageal damage and even cancer. James Callaway, MD, a gastroenterologist, and Kristen Wong, MD, a surgeon, discuss the progressive steps they take in diagnosing, managing, and treating GERD. Dr. Calloway emphasizes that controlling weight and diet are always top priorities for anyone with recurring acid reflux, while proton pump inhibitors remain effective prescription medications. Dr. Wong discusses surgical gastric modifications and devices for patients who do not respond to medication.