Thorax Podcast artwork

Thorax Podcast

73 episodes - English - Latest episode: 16 days ago - ★★★★ - 1 rating

Thorax, the official journal of the British Thoracic Society, publishes influential clinical and experimental research in respiratory medicine, paediatrics, immunology, pharmacology, pathology, and surgery. The focus is on work that advances scientific understanding and impacts clinical practice.
http://thorax.bmj.com/

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Episodes

Invitation strategies in lung cancer screening, with Dr. Patrick Goodley

March 13, 2024 05:00 - 21 minutes - 19.7 MB

Socioeconomic deprivation is a driving factor in lung cancer rates. With the roll out of a national lung cancer screening programme in the UK, it's important that the right invitation strategies are used for reaching community members who may be at risk. This episode, Dr. Patrick Goodley (@patrick_goodley) joins host Dr. Kate Diomede to discuss the recent paper, "Invitation strategies and participation in a community-based lung cancer screening programme located in areas of high socioeconomi...

Female reproductive history and COPD risk, with Prof. Gita Mishra

February 13, 2024 23:30 - 24 minutes - 22.2 MB

What impact do reproductive events, like menarche, miscarriage or menopause have on female lung health? Prof. Gita Mishra (1) joins Thorax host Dr. Kate Diomede to discuss this question. They consider how recurrent fertility issues can point to an increased risk of chronic obstructive pulmonary disease later in life, and how variance in oestrogen levels throughout the lifespan affect lung development. The conversation is centred around the recently-published study, "Female Reproductive Histo...

Immediate smoking cessation support during lung cancer screening, with Parris Williams

January 15, 2024 11:43 - 23 minutes - 22 MB

Lung cancer screening in the UK has only been introduced in recent years, and its processes around smoking cessation guidance may have opportunities for improvement. Visiting the studio today is PhD student Parris Williams (1), to discuss the newly published Thorax research paper, "Immediate smoking cessation support during lung cancer screening: long-term outcomes from two randomised controlled trials" (https://thorax.bmj.com/content/early/2023/10/24/thorax-2023-220367). Along with social me...

Comparing COVID detection rates for oral and nasal swabs, with Dr. Tobias Todsen

November 24, 2023 05:00 - 35 minutes - 32.5 MB

Head and neck consultant Dr. Tobias Todsen (1) joins the podcast from Copenhagen to speak with social media editor Dr. Kate Diomede. The topic of conversation is the recent paper, "Higher SARS-CoV-2 detection of oropharyngeal compared with nasopharyngeal or saliva specimen for molecular testing: a multicentre randomised comparative accuracy study" (https://thorax.bmj.com/content/78/10/1028). They discuss the sensitivity of different test combinations, cultural inclinations for certain kinds o...

Linking obesity and asthma, with Dr. Hayley Scott

October 20, 2023 11:39 - 21 minutes - 20.1 MB

In a conversation touching on diet, fat distribution, and inflammatory pathways, Dr. Hayley Scott (1) speaks with host Dr. Kate Diomede about the recent paper, “Effect of obesity on airway and systemic inflammation in adults with asthma: a systematic review and meta-analysis". Read the article here: https://thorax.bmj.com/content/78/10/957  (1) School of Biomedical Sciences and Pharmacy, The University of Newcastle, NSW, Australia Please engage in the conversation through the social media...

Community-acquired pneumonia readmissions, with Dr. Wei Shen Lim

September 19, 2023 16:13 - 23 minutes - 21.3 MB

Dr. Wei Shen Lim (1) joins Thorax's podcast host and social media editor Dr. Kate Diomede to talk over the recent research paper, “Readmission following hospital admission for community-acquired pneumonia in England”. Read the article here: https://thorax.bmj.com/content/early/2023/07/28/thorax-2022-219925 (1) Department of Respiratory Medicine, Nottingham University Hospitals NHS Trust, Nottingham, UK Please engage in the conversation through the social media channels (Twitter - @ThoraxB...

Preterm birth and bronchopulmonary dysplasia, with Dr. Elizabeth Smith

August 17, 2023 14:26 - 13 minutes - 12.1 MB

Dr. Kate Diomede, podcast host and Thorax social media editor, is joined by Dr. Elizabeth Smith (1) to discuss a study on the longterm respiratory outcomes for survivors of very preterm birth, titled "Risk factors for poorer respiratory outcomes in adolescents and young adults born preterm." Read the article here: https://thorax.bmj.com/content/early/2023/05/18/thorax-2022-219634  Find more info on the team's work at: https://walyanrespiratory.telethonkids.org.au/news-and-events/2023/may/W...

New BTS pleural disease guideline, with Prof. Najib Rahman and Prof. Nick Maskell

July 18, 2023 15:04 - 27 minutes - 25.2 MB

Dr. Kate Diomede, podcast host and Thorax social media editor, is joined by Prof. Najib Rahman (1) and Prof. Nick Maskell (2) to discuss the July 2023 update of the British Thoracic Society's guideline for treatment of pleural disease. This document was last updated in 2010, and now accounts for the high quality data provided by more recent trials, as well as modern practices informed by those. Read the guideline here: https://thorax.bmj.com/content/78/Suppl_3/s1 (1) Oxford Respiratory Tri...

Lung cancer screening with Dr. Sam Janes

June 16, 2023 12:03 - 21 minutes - 19.6 MB

Dr. Kate Diomede, social media editor at Thorax, is joined by Dr. Sam Janes (1) to discuss the history of lung cancer screening, and its use in early detection. They also examine the process and results of his recent paper, "Growing small solid nodules in lung cancer screening: safety and efficacy of a 200 mm3 minimum size threshold for multidisciplinary team referral". The paper is available online: https://thorax.bmj.com/content/78/2/202 (1) Lungs for Living Research Centre, UCL Respirato...

Not all vaping is the same: CBD vs nicotine

June 02, 2023 09:59 - 28 minutes - 25.7 MB

Dr. Kate Diomede, social media editor at Thorax, is joined by Dr. Yasmin Thanavala (1) to discuss her group's recent research paper, "Not all vaping is the same: differential pulmonary effects of vaping cannabidiol versus nicotine". Their study used a using a mouse model of vaping and in vitro experiments with human cells. The paper is available online: https://thorax.bmj.com/content/early/2023/04/02/thorax-2022-218743 Hear the previous discussion with Prof. Nick Hopkinson on policy relatin...

Smoking and vaping: policy and challenges with Nick Hopkinson

April 17, 2023 21:23 - 25 minutes - 23.3 MB

Dr. Kate Diomede, social media editor at Thorax, is joined by Prof. Nick Hopkinson(1) to delve into the history of smoking policy in the UK, as well as detailing the lay of the land in current smoking-cessation practices, especially pertaining to vaping. Hear the previous discussion with Prof. Andrew Bush on recent developments in paediatric therapy: https://on.soundcloud.com/PY9Nz (1) Prof. of Respiratory Medicine, Imperial College London, Respiratory Consultant, Royal Brompton Hospital, ...

Recent developments in paediatric therapy with Prof. Andrew Bush

March 10, 2023 01:12 - 19 minutes - 17.5 MB

In this episode Dr. Kate Diomede, social media editor at Thorax, speaks with Prof. Andrew Bush(1) about the state of paediatric treatment for thoracic issues, including discussion of cystic fibrosis and asthma. Hear the previous discussion with Prof. Ian Hall on the future of respiratory medicine: https://on.soundcloud.com/yb7pJ (1) Consultant paediatric chest physician at Royal Brompton Hospital; Professor of paediatric respirology, National Heart and Lung Institute, Imperial College Londo...

MUC5B, telomere length and longitudinal quantitative interstitial lung changes: the MESA Lung Study

February 10, 2023 18:21 - 15 minutes - 14.2 MB

Dr. Kate Diomede, social media editor at Thorax, speaks with Dr. Anna Podolanczuk(1) and Dr. John Kim(2) about their article, "MUC5B, telomere length and longitudinal quantitative interstitial lung changes: the MESA Lung Study", published in Thorax: https://thorax.bmj.com/content/early/2022/08/04/thorax-2021-218139 Please engage in the conversation through the social media channels (Twitter - @ThoraxBMJ; Facebook - @Thorax.BMJ · Pulmonologist) and subscribe on your preferred platform, to get...

Live from the British Thoracic Society (BTS) Winter Meeting 2022

January 17, 2023 17:26 - 9 minutes - 8.63 MB

Thorax social media editor, Dr. Puja Mehta, caught up with several Respiratory consultants from across the UK at the British Thoracic Society (BTS) Winter Meeting 2022, and asked them the question, 'What makes the Winter BTS meeting special?' Please engage in the conversation through the social media channels (Twitter - @ThoraxBMJ; Facebook - @Thorax.BMJ · Pulmonologist) and subscribe on your preferred platform, to get the latest episodes directly on your device each month. If you enjoy the...

Respiratory research in the UK: investing for the next 10 years

December 12, 2022 23:03 - 26 minutes - 24.6 MB

In this episode, Thorax social media editor Dr. Puja Mehta speaks with Professor Ian Hall, Director of the Nottingham Biomedical Research Centre and the University of Nottingham about his paper "Respiratory Research in the UK: investing for the next 10 years". They discuss some of the biggest challenges facing respiratory research in the UK, and why respiratory diseases need more investment. Read the paper here: https://thorax.bmj.com/content/77/9/851 Please engage in the conversation throug...

The Thorax Podcast is back! Meet the new Editors

November 01, 2022 17:40 - 7 minutes - 7.28 MB

Welcome back to the Thorax Podcast, home to the discussion of new research and hot topics in respiratory research and clinical practice. In this first episode, we introduce you to the three new Editors of the Thorax journal: Dr. Mark Griffiths and Dr. Jennifer Quint, both from Imperial College London, and Dr. Cecilia O'Kane, from Queen's University Belfast. They outline plans for the Thorax journal, including the social media strategy and engaging readers and trainees. You'll also get to kn...

Better asthma control, half of the carbon footprint with climate-friendly inhalers

January 31, 2022 18:07 - 7 minutes - 6.9 MB

In this podcast, Rachael Moses, Multimedia Editor of Thorax BMJ, is joined by Professor Ashley Woodcock, Manchester Academic Health Sciences Centre, The University of Manchester, UK, to discuss the paper "Effects of switching from a metered dose inhaler to a dry powder inhaler on climate emissions and asthma control: post-hoc analysis." This paper was a secondary analysis of the Salford Lung Study in Asthma. In a real world study SLS asthma showed that a once daily combination treatment in a...

What are the risks from 'aerosol-generating procedures’ in the treatment of patients with COVID-19?

November 26, 2021 11:48 - 10 minutes

Do hospitalised COVID-19 patients receiving treatment with CPAP and HFNOT present a significant added risk of viral contamination to the surrounding environment used by healthcare workers? And is there enough evidence to suggest or recommend levels of PPE that should be used for healthcare workers caring for patients on CPAP or HFNOT? Two of the main questions this short podcast addresses. Rachael Moses, Multimedia Editor Thorax BMJ, interviews Dr Chris Green, Consultant in Infectious Disease...

What are the risks from ’aerosol-generating procedures’ in the treatment of patients with COVID-19?

November 26, 2021 11:48 - 10 minutes - 9.51 MB

Do hospitalised COVID-19 patients receiving treatment with CPAP and HFNOT present a significant added risk of viral contamination to the surrounding environment used by healthcare workers? And is there enough evidence to suggest or recommend levels of PPE that should be used for healthcare workers caring for patients on CPAP or HFNOT? Two of the main questions this short podcast addresses. Rachael Moses, Multimedia Editor Thorax BMJ, interviews Dr Chris Green, Consultant in Infectious Disease...

Cigarettes and COVID-19: clearing the smoke

October 06, 2021 08:13 - 8 minutes - 7.89 MB

In this podcast, Rachael Moses, Multimedia Editor of Thorax BMJ, talks to Dr Ash Clift Nuffield Department of Primary Care Health Sciences, University of Oxford. The evidence surrounding COVID-19 has been conflicting and inconsistent. This podcast discusses the findings of this observational and Mendelian randomisation study using the UK Biobank cohort. The author discusses the findings with regards to the potential causal effect of cigarette smoking on the severity of COVID-19 infection and ...

Do financial incentives improve key COPD outcomes?

August 19, 2021 11:15 - 6 minutes - 6.15 MB

In this podcast, we discuss the impact of Best Practice Tariffs (BPT) in improving outcomes for people with COPD admitted to hospital following an acute exacerbation. The key question was to understand if the combination of specialist review within 24 hours and a discharge care bundle incentivised by the English COPD BPT scheme was associated with improved mortality and readmission rates for those admitted with an acute exacerbation of COPD. Thorax Multimedia Editor, Rachael Moses, talks to P...

The BCG Vaccine Programme: Are we getting it right?

June 02, 2021 09:47 - 8 minutes - 7.54 MB

In this podcast, Rachael Moses, Multimedia Editor of Thorax BMJ, talks to Professor James Trauer, Epidemiological Modelling Unit, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia. Tuberculosis is the world’s leading infectious disease killer with the BCG vaccine being the only approved vaccine for its control. The paper on hand was a systematic review of studies looking at the effect of BCG vaccination on TB disease, including sub-categories of TB dise...

Sleep Vibrations: Can a positional therapy device improve outcomes in obstructive sleep apnoea?

May 05, 2021 19:11 - 11 minutes - 10.6 MB

In this podcast Rachael Moses, MultiMedia Editor Thorax BMJ talks to Ms Laura Hidalgo Armas, OSI Araba Hospital University, Vitoria, Spain. They discuss the effectiveness of a new vibrational positional device located on the forehead on reducing the apnea-hypopnea index and total sleep time in the supine position for patients with obstructive sleep apnea. Links to related papers: https://thorax.bmj.com/content/early/2021/04/21/thoraxjnl-2020-216167

Smoking cessation at work: Do heated tobacco products work?

April 15, 2021 14:51 - 6 minutes - 14.9 MB

In this podcast, Rachael Moses, Multimedia Editor of Thorax, is joined by Dr Makiko Kanai, National Hospital Organisation Kyoto Medical Center, Japan, to discuss how a smoking cessation pathway was trialed in a Japanese workplace using heated tobacco products. Listen to a related podcast on the SUR-VAPES Study (https://soundcloud.com/bmjpodcasts/the-sur-vapes-study?in=bmjpodcasts/sets/thorax) Links to related papers: https://thorax.bmj.com/lookup/doi/10.1136/thoraxjnl-2020-215900 https://thor...

The SUR-VAPES Study

April 15, 2021 14:48 - 7 minutes - 18.1 MB

In this podcast, Rachael Moses, Multimedia Editor of Thorax BMJ, talks to Professor Lorenzo Loffredo, Sapienza University of Rome, Italy. They discuss the impact of chronic use of heat-not-burn cigarettes on oxidative stress, endothelial dysfunction and platelet activation. This is also known as the SUR-VAPES Chronic Study. Are these products safer than smoking? Listen to a related podcast on smoking cessation at work and heated tobacco (https://soundcloud.com/bmjpodcasts/smoking-cessation-at...

Ivacaftor: Long term adherence and outcomes

March 26, 2021 16:58 - 11 minutes - 10.3 MB

The recent development of triple CFTR modulation means that up to 90% of people with CF will be eligible for ‘highly effective’ CFTR modulator therapy. In this podcast, Rachael Moses, Multimedia Editor of Thorax, and Dr Peter Barry, Consultant Respiratory Physician, Manchester Adult Cystic Fibrosis Centre, discuss the long-term adherence to and effects of ivacaftor on lung function, weight and healthcare utilisation in people with cystic fibrosis and the Gly551Asp mutation. Read the related ...

Meat Consumption and Childhood Wheeze: The implications of Western Diet

January 02, 2021 15:31 - 5 minutes - 7.49 MB

Multimedia Editor of Thorax, Rachael Moses, interviews Dr Sonali Bose, Faculty in the Division of Pulmonary, Critical Care Medicine and Sleep Medicine, New York. They discuss the relationship between western diet, particularly increased advanced glycation end product and meat consumption, in childhood wheeze and the public health implications of the findings. Read the related articles: https://thorax.bmj.com/content/early/2020/11/22/thoraxjnl-2020-216109 https://thorax.bmj.com/content/early/...

Hormonal Contraception and severe asthma exacerbation: Is there a link?

October 26, 2020 17:38 - 10 minutes - 14.5 MB

In this podcast, the effect of hormonal contraception on the impact of severe asthma exacerbation in women of reproductive age is discussed. Multimedia Editor of Thorax, Rachael Moses, interviews Dr Nwaru, Associate Professor of epidemiology, Krefting Research Centre, University of Gothenburg, Sweden, author of the longest longitudinal study investigating this impact in women with established asthma. (https://thorax.bmj.com/content/early/2020/10/15/thoraxjnl-2020-215540)

No Symptoms? Why wearing a mask still matters

September 09, 2020 11:50 - 7 minutes - 10.5 MB

We discuss the viral load of asymptomatic and mildly symptomatic patients with SARS-CoV-2 infection and the potential protracted course of COVID-19 infection than initially thought. The data within this study further supports the use of face masks in the community to prevent the further spread of COVID-19. Read the paper: https://thorax.bmj.com/content/early/2020/08/28/thoraxjnl-2020-215042

Behind the mask: COVID-19 exposure and viral carriage in healthcare workers

August 27, 2020 17:51 - 11 minutes - 15.5 MB

This podcast discusses the exposure and potential viral carriage of healthcare workers in a large UK Hospital. It also discusses the impact of exposure, the importance of personal protective equipment and how we can use the findings ot help prepare for future pandemics. Read the article on the Thorax website: http://dx.doi.org/10.1136/thoraxjnl-2020-215414

COVID-19: In the footsteps of Ernest Shackleton

May 26, 2020 13:27 - 11 minutes - 26.9 MB

An expedition ship departed on an Antarctic cruise mid-March 2020 with no known COVID passengers or crew members. However after 8 days the first passenger became febrile and isolation procedures were followed. A further 24 members of the ship developed symptoms (some as late as 23 days later) with 8 requiring medical evacuation. Of the 217 passengers and crew on board, 128 tested positive for COVID-19 with 81% of those positive being asymptomatic. This paper demonstrates how quickly COVID-19 ...

Childhood obstructive sleep apnea: Its more than a snore

March 01, 2020 17:01

Childhood obstructive sleep apnea (OSA) is an independent determinant of blood pressure in adulthood – a longitudinal follow-up study’ with host Rachael Moses and Dr Kate Chan, Chinese University of Hong Kong. This podcast discusses the relationship between Childhood OSA and adverse BP in adulthood as well as the long term health implications and why it is important this is treated. Read the paper on the Thorax website: https://thorax.bmj.com/content/early/2020/03/23/thoraxjnl-2019-213692

Childhood obstructive sleep apnoea: it's more than a snore

March 01, 2020 17:01 - 7 minutes

Childhood obstructive sleep apnoea (OSA) is an independent determinant of blood pressure in adulthood – a longitudinal follow-up study’ with host Rachael Moses and Dr Kate Chan, Chinese University of Hong Kong. This podcast discusses the relationship between Childhood OSA and adverse BP in adulthood as well as the long term health implications and why it is important this is treated. Read the paper on the Thorax website: https://thorax.bmj.com/content/early/2020/03/23/thoraxjnl-2019-213692

Childhood obstructive sleep apnoea: it’s more than a snore

March 01, 2020 17:01 - 7 minutes - 9.71 MB

Childhood obstructive sleep apnoea (OSA) is an independent determinant of blood pressure in adulthood – a longitudinal follow-up study’ with host Rachael Moses and Dr Kate Chan, Chinese University of Hong Kong. This podcast discusses the relationship between Childhood OSA and adverse BP in adulthood as well as the long term health implications and why it is important this is treated. Read the paper on the Thorax website: https://thorax.bmj.com/content/early/2020/03/23/thoraxjnl-2019-213692

Smoking in cars: how the recent ban is affecting young people in England and Scotland

January 27, 2020 15:48 - 8 minutes - 12 MB

Smoking with children in a car has been illegal since 2015 in England and 2016 in Scotland. This podcast explores the importance and impact of this ban on children and the important message it gives to the public to ensure smoking rates continue to fall. Listen to the conversation between Rachael Moses and Dr Anthony Laverty, Public Health Policy Evaluation Unit, School of Public Health, Imperial College London, London, UK and lead author of https://thorax.bmj.com/content/early/2020/01/08/th...

Overweight and out of breath: cause and effect?

October 08, 2019 10:06 - 10 minutes - 14.7 MB

In this podcast, Multimedia Editor of Thorax Rachael Moses, discusses with Dr Magnus Ekstrom, Lund University, Sweden, the key findings of a population-based study investigating the relationship between increased body mass index with breathlessness and lung function. Read the paper on the Thorax website: https://thorax.bmj.com/content/74/10/958.

The role of sex hormones on the development of asthma

February 10, 2019 13:37 - 6 minutes - 8.4 MB

The study discussed in this podcast introduces evidence that supports a biological explanation behind the observed asthma discordance between males and females. Read the paper on the Thorax website: https://thorax.bmj.com/content/early/2019/01/29/thoraxjnl-2018-212207

Assisted reproductive technologies and asthma risk in children

October 18, 2018 16:55 - 4 minutes - 5.74 MB

Assisted reproduction techniques might increase asthma risk in children conceived this way, a study published by Thorax concludes. Maria Magnus, Centre for Fertility and Health, Norwegian Institute of Public Health, talks with Thorax podcast editor Rachel Moses about her research group findings, that you can also read for free at http://dx.doi.org/10.1136/thoraxjnl-2018-211886. A related editorial can also be found on the journal website (thorax.bmj.com).

How toxic is your vape?

August 08, 2018 16:32 - 9 minutes - 12.6 MB

The study discussed in this podcast cautions against the widely held opinion that e-cigarettes are safe. Listen to the conversation between the Multimedia Associate Editor of Thorax Rachael Moses and Professor David Thickett (Institute of Inflammation and Ageing, University of Birmingham, UK) and read the study 'Pro-inflammatory effects of e-cigarette vapour condensate on human alveolar' on the Thorax website: https://thorax.bmj.com/ You can subscribe to the Thorax Podcast in all major podca...

Growing up on a farm as related to adult lung function and allergic phenotypes

August 24, 2016 10:10 - 7 minutes - 10.9 MB

In this podcast Jennifer Quint talks to Shyamali Dharmage and Brittany Campbell about their recent press released paper "Growing up on a farm as related to adult lung function and allergic phenotypes: An international population based study".

Air Pollution affects Lung Cancer Survival

July 25, 2016 16:38 - 5 minutes - 7.22 MB

Patients exposed to air pollution after diagnosis of lung cancer have shorter survival, in particular those patients with early-stage non-small cell cancers (specially adenocarcinomas), according to a study published by Thorax and conducted by researchers from the Department of Preventive Medicine, University of Southern California. The first study of this kind was based on a population of over 300 thousand patients with newly diagnosed lung cancer over more than two decades. In this podcas...

Air pollution and the London low emission zone

November 17, 2015 15:11 - 14 minutes - 19.9 MB

In this podcast Dr Ian Mudway talks to Dr Elizabeth Batalla-Duran about his recent paper in Plos-One entitled "Effects of air pollution and introduction of the London low emission zone on the prevalence of respiratory and allergic symptoms on the school children of East London".

E-cigarette use and smoking in early adolescence

September 30, 2015 15:00 - 14 minutes - 19.3 MB

In this podcast Dr Elizabeth Batalla-Duran talks to Dr Adam Leventhal from the University Southern California about his paper "Association of Electronic Cigarette Use With Initiation of Combustible Tobacco Product Smoking in Early Adolescence" recently published in JAMA.

Long-term experience with rituximab in anti-synthetase syndrome-related interstitial lung disease

September 29, 2015 13:50 - 9 minutes - 13.1 MB

In this podcast Dr Janice Higginson talks to Dr Helena Anderson from Oslo University Hospital about her recent paper published in Rheumatology. The paper is a retrospective review of research done into rituximab's effect on the rare Antisynthetase Syndrome.

Pneumococcal vaccination for welders

October 01, 2014 15:52 - 9 minutes - 6.31 MB

Thorax deputy editor Paul Cullinan talks to David Coggon, MRC Lifecourse Epidemiology Unit, University of Southampton, about pneumococcal vaccination for welders. Read the full article: http://goo.gl/p3qN8s

The genomic origins of asthma

July 08, 2014 12:55 - 14 minutes - 9.72 MB

Ian Pavord talks to Scott Weiss, Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, about his review on the genomic origins of asthma, which considers several areas where environmental exposures, genomics, development and asthma occurrence overlap. Read the full review: http://goo.gl/KctouZ

The promise of translational and personalised approaches for paediatric obstructive sleep apnoea

May 14, 2014 09:21 - 19 minutes - 13.5 MB

Obstructive sleep apnoea (OSA) can result in significant morbidities including the cardiovascular, metabolic and neurocognitive systems. While great advances have been made in sleep medicine research in the past decades, there are still wide gaps in our knowledge concerning the exact underlying pathophysiological mechanisms of OSA and consequences. A recent review in Thorax discusses the recent exciting discoveries in genotype-phenotype interactions, epigenetics, genomics and proteomics re...

TB special: The ins and outs of interferon-gamma release assays

May 01, 2013 14:49 - 15 minutes - 20.9 MB

We are delighted to present a podcast recording of an interview with Professor Ajit Lalvani to coincide with the TB special edition of Thorax in March. He describes the development of the FDA-approved, NICE and CDC-endorsed interferon-gamma release assay (IGRA, ELISpot, T-SPOT.TB) which he invented and validated as the first advance in diagnosis of latent TB in 100-years. He will discuss new findings using this assay published in the March issue of Thorax, and the prospects for improved immun...

Journal club: Surgical resection for stage I and II small cell carcinoma of the lung

February 13, 2013 16:59 - 6 minutes - 9.62 MB

Benny Weksler, associate professor of surgery, Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, talks to Jennifer Quint, Thorax journal club editor, about surgery for small cell carcinoma of the lung. See also: http://ats.ctsnetjournals.org/cgi/content/abstract/94/3/889

Journal club: Raised glucose levels predict death for patients with pneumonia

February 13, 2013 16:58 - 6 minutes - 8.83 MB

Jennifer Quint, Thorax’s journal club editor, talks to Philipp Lepper, consultant physician, University Hospital of Saarland, Germany, about his study which revealed glucose levels can predict mortality in patients admitted with community acquired pneumonia. See also: http://www.bmj.com/content/344/bmj.e3397

Twitter Mentions

@thoraxbmj 8 Episodes
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