TWiV 995: Viral origin stories

TWiV discusses genetic evidence of susceptible wildlife in SARS-CoV-2 positive samples at the Huanan Wholesale Seafood Market, polio cases in African linked to a new polio vaccine that was designed to not cause the disease, and structural conservation of hepatitis B virus capsid proteins over millions of years despite a shift from a naked to an enveloped capsid.

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Download TWiV 995 (74 MB .mp3, 123 min)
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•Register for ASV 2023
•MicrobeTV Discord Server
• More evidence for SARS-CoV-2 spillover (Zenodo)
•Polio cases linked to nOPV2 (Science; GPEI statement)
•nOPV2 on TWiV 756
•Engineering OPV to prevent reversion to neurovirulence (Cell Host Microbe)
•Stability of nOPV2 in children (npj Vaccines)
•2A changes compensate for 5′-UTR disruptions (Virology)
•HBV shifts from naked to enveloped (Nat Comm)
•Letters read on TWiV 995
•Timestamps by Jolene. Thanks!

Dickson – Jazz Project: Bass: Ray Brown, Ron Carter, Percy Heath
Angela – The nervous system may play a role in severe allergic reactions through immune cell (mast cells) cross-talk with neurons
Brianne – Science Museums Take Stock of 1.1 Billion Objects from Around the World
Vincent – Architect Breaks Down 5 of the Most Common Skyscraper Styles In New York

Gary – Tony Fauci on PBS
Stefanie – What Do You Find Beautiful about Viruses? A Post-COVID Assessment Strategy

Intro music is by Ronald Jenkees

Send your virology questions and comments to [email protected]