This Week in Neuroscience artwork

This Week in Neuroscience

48 episodes - English - Latest episode: about 1 month ago - ★★★★★ - 75 ratings

A podcast about the nervous system.

Life Sciences Science Natural Sciences
Homepage Apple Podcasts Google Podcasts Overcast Castro Pocket Casts RSS feed

Episodes

TWiN 48: Traumatic brain injury and retroviruses

February 19, 2024 05:00 - 51 minutes - 35.8 MB

TWiN describes a study that reveals activation of endogenous retroviruses in oligodenroglia from patients with traumatic brain injury.  Hosts: Vincent Racaniello, Jason Shepherd, and Timothy Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode MicrobeTV Discord Server Activation of endogenous retroviruses in TBI oligodendroglia (Cell Rep) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees Send your neuroscience questions and comments to tw...

TWiN 47: Walking after spinal cord injury

January 29, 2024 05:00 - 55 minutes - 38.7 MB

TWiN explains an amazing study of a man who was paralyzed after a spinal cord injury and regained the ability to walk after implantation of a brain-spinal cord interface.  Hosts: Vincent Racaniello, Jason Shepherd, and Timothy Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode MicrobeTV Discord Server Walking naturally after spinal cord injury (Nature) The paralyzed rat that walked (YouTube) Mike the headless chicken (Wikipedia) Timestamps by...

TWiN 46: Neuronal activity promotes glioma progression

January 01, 2024 22:13 - 51 minutes - 35.7 MB

TWiN explains research showing that interaction between glioma cells and neurons in the brain shares mechanistic features with synaptic plasticity that contributes to memory and learning in the healthy brain.  Hosts: Vincent Racaniello, Jason Shepherd, and Timothy Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode MicrobeTV Discord Server Glioma synapses recruit mechanisms of adaptive plasticity (Nature) Timestamps by Jolene. Thanks! Music is by ...

TWiN 45: Acupuncture modulates the immune system

December 13, 2023 18:07 - 52 minutes - 36.6 MB

TWiN discusses research showing that sciatic nerve activation with electroacupuncture at the sciatic nerve controls systemic inflammation and rescues mice from polymicrobial peritonitis, by inducing vagal activation of aromatic L-amino acid decarboxylase, leading to the production of dopamine in the adrenal medulla.  Hosts: Vincent Racaniello, Jason Shepherd, and Timothy Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode MicrobeTV Discord Server El...

TWiN 44: ADHD and persistent pain

November 02, 2023 22:03 - 1 hour - 42.3 MB

TWiN reviews a mouse model of ADHD to characterize hypersensitivity to pain, and that sensitization is further amplified in a pathological inflammatory state. Hosts: Vincent Racaniello, Jason Shepherd, and Timothy Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode MicrobeTV Discord Server Pain hypersensitivity in ADHD model (PNAS) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@mic...

TWiN 43: Pavlovian opioid tolerance

October 04, 2023 15:34 - 1 hour - 43.7 MB

TWiN discusses a study of on the pathways that control opioid analgesic tolerance, a root cause of opioid overdose and misuse, which can develop through an associative learning. Hosts: Vincent Racaniello, Jason Shepherd, and Timothy Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode MicrobeTV Discord Server Associative opioid analgesic tolerance (Sci Adv) Pavlovian-conditioned opioid tolerance (Sci Adv) Timestamps by Jolene. Thanks! Music is b...

TWiN 42: Therapeutic effects of psychedelic drugs

July 18, 2023 02:02 - 56 minutes - 33 MB

TWiN explains how psychedelic drugs such as LSD, psilocybin, and MDMA, which are being explored for treating a wide range of neuropsychiatric diseases, reopen the social reward period for critical learning. Hosts: Vincent Racaniello, Jason Shepherd, and Timothy Cheung Click arrow to play Download TWiN 042 (34 MB .mp3, 57 min) Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode MicrobeTV Discord Server Psychedelic drugs open critical period (Nature) Psyc...

TWiN 41: Alzheimer's and melanin-concentrating hormone

June 20, 2023 04:00 - 1 hour - 45.5 MB

Vivianne explains how early in Alzheimer’s disease, the brain attempts to counteract the increased excitatory drive caused by amyloid deposition, and that melanin-concentrating hormone, produced during sleep, is involved in this protective response. Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode MicrobeTV Discord Server Melanin-concentrating hormone and Alzheimer’s diseas...

TWiN 40: Dopamine organizes behavior's syllables

May 11, 2023 17:20 - 1 hour - 37.4 MB

Tim takes TWiN through two studies on the role of dopamine: that syllables are natural units of spontaneous behavior used by the brain to structure action, and that mesolimbic dopamine release conveys causal associations but not reward prediction errors, thereby challenging the dominant theory of reward learning. Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode MicrobeTV Disc...

TWiN 39: Virus-like capsids trigger paraneoplastic disease

April 28, 2023 11:30 - 52 minutes - 30.1 MB

Junjie from Jason’s lab joins TWiN to discuss the observation that the cell gene PNMA2 encodes non-enveloped virus-like capsids that induce autoantibodies which underlie paraneoplastic syndrome. Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Junjie Xu Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode MicrobeTV Discord Server Virus-like capsids in paraneoplastic disease (bioRxiv) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees ...

TWiN 38: Bacterial immunity heals sensory neurons

March 27, 2023 04:00 - 1 hour - 37.8 MB

TWiN explains the finding that immunity to commensal bacteria promotes sensory neuron regeneration via the cytokine interleukin-17A. Hosts: Vincent Racaniello, Ori Lieberman, Timothy Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode MicrobeTV Discord Server Immunity to the microbiota promotes sensory neuron regeneration (Cell) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees Send your neuroscience questions and ...

TWiN 37: Microglia at the crossroads

January 23, 2023 05:00 - 1 hour - 43.6 MB

TWiN reviews the field of microgial research, which has advanced in recent decades but is constrained by nomenclature that is necessary but often implies specific functions. Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode Microglia states and nomenclature (Nature) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees Send your neuroscience questions and comments to tw...

TWiN 36: Unbearable neurologists

January 03, 2023 21:43 - 1 hour - 51.9 MB

TWiN answers listener questions about Alzheimer’s disease, glaucoma and the microbiota, Dravet’s Syndrome, schizophrenia, brain development, and chips implanted in the human brain. Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS Links for this episode Letters read on TWiN 36 Timestamps by Jolene. Thanks! Music is by Ronald Jenkees Send your neuroscience questions and comments to [email protected]

TWiN 35: Neuromodulation in treatment-resistant depression

December 06, 2022 21:03 - 1 hour - 40.2 MB

Jason and Tim review the use of an implanted chronic deep brain sensing and stimulation device to carry out biomarker-driven closed-loop therapy that resulted in a rapid and sustained improvement in depression.  Hosts: Jason Shepherd and Timothy Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Closed-loop neuromodulation for depression (Nat Med) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees Send your neuroscience questions and...

TWiN 34: Microglia vital after spinal cord injury

September 30, 2022 04:00 - 1 hour - 39.6 MB

TWiN explains how central nervous system resident macrophages known as microglia coordinate cellular interactions during spinal cord repair in mice. Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Microglia coordinate spinal cord repair (Nat Commun) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@micro...

TWiN 33: Viruses leaving the brain

August 31, 2022 14:02 - 58 minutes - 33.9 MB

TWiN describes how neurotropic viruses leave the brain via meningeal lymphatic vessels located dorsally and basally beneath the skull. Hosts: Vincent Racaniello, Ori Lieberman, Jason Shepherd, and Timothy Cheung Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Meningeal lymph vessels and viral exit from brain (Nature Neuroscience) Clearing mouse brain video (YouTube) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees Send your neurosci...

TWiN 32: Relearning how to move after stroke

August 02, 2022 22:44 - 59 minutes - 34.2 MB

TWiN reviews how, in a mouse stroke model, recovery of movement is associated with the remaining cortex and the striatum coordinating their activity together. Hosts: Ori Lieberman, Timothy Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Recovery after stroke in mice (Cell Rep) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees Send your neuroscience questions and comments to [email protected]

TWiN 31: HIV-1 co-receptor shapes window for memory linking

June 29, 2022 17:07 - 1 hour - 41.1 MB

TWiN explains the observation that in mice, the HIV-1 co-receptor CCR5 closes the temporal window for linking different memories. Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode CCR5 and memory linking (Nature) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees Send your neuroscience questions and comments to [email protected]

TWiN 30: Gut to brain spread of alpha-synuclein in Parkinson's disease

May 24, 2022 19:53 - 1 hour - 40 MB

TWiN describes experiments demonstrating that gut injection of alpha-synuclein fibrils in mice converts endogenous alpha-synuclein to a pathologic form that spreads to the brain and leads to features of Parkinson’s disease. Hosts: Vincent Racaniello, Ori Lieberman, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Links for this episode Gut-brain alpha-synuclein transport in PD (Neuron) Gut has a mind of its own (Col...

TWiN 29: Astrocytes close the critical period

May 02, 2022 19:43 - 1 hour - 36.2 MB

TWiN explains the finding that in the mouse visual cortex, astrocytes are key elements in the experience-dependent wiring of brain circuits. Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Astrocytes close the critical period (Science) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees Send your neuroscience questions and comments to...

TWiN 28: Oligodendrocyte performance enhancing exosomes

April 04, 2022 17:45 - 1 hour - 42.3 MB

TWiN reveals how oligodendrocytes enhance axonal energy metabolism by transcellular delivery of a protein, SIRT2, that deacetylates mitochondrial proteins. Hosts: Vincent Racaniello, Timothy Cheung, and Vivianne Morrison Click arrow to play Download TWiN 028 (77 MB .mp3, 64 min) Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Glia 101 (TWiN 19) Oligodendrocytes enhance axonal energy metabolism (Neuron) Timestamps by...

TWiN 27: Eyes wired to the auditory cortex

March 03, 2022 20:41 - 1 hour - 73 MB

TWiN discusses the finding that rewiring retinal projections to the auditory thalamus in ferrets leads to visually responsive cells that are typical of cells in the visual cortex. Hosts: Ori Lieberman, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Remapping retinal projections (Nature) Sweet vs bitter taste (Nature) Timestamps by Jolene. Thanks! Music is by Rona...

TWiN 26: Immunological memory in the brain

January 31, 2022 13:06 - 53 minutes - 30.8 MB

TWiN reviews evidence in mice that brain neurons encode and retrieve specific immune responses. Become a patron of TWiN! Links for this episode Memory of immunity (Cell) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees Send your neuroscience questions and comments to [email protected]

TWiN 25: Thanks for listening

December 28, 2021 12:17 - 1 hour - 72.4 MB

TWiN answers listener questions on sex in neuroscience studies, rotating memories in the brain, odorant receptors in the brain, and neutrophils that promote neuron survival. Hosts: Vincent Racaniello, Jason Shepherd, and Timothy Cheung Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Males and females in neuroscience studies (New Scientist) Brain rotates memories (Quanta) Odorant receptors in brain (one, two) Neutrophils p...

TWiN 24: Social transmission of maternal behavior with Ioana Carcea and Robert Froemke

November 24, 2021 19:38 - 1 hour - 42.3 MB

Ioana and Robert join TWiN to discuss their work demonstrating that rodents acquire maternal behavior by social transmission from an experienced mother to a virgin female how to care for a litter via endogenous oxytocin. Hosts: Vincent Racaniello and Timothy Cheung Guests: Ioana Carcea and Robert Froemke Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Oxytocin neurons and social transmission of behavior (Nature) Timestamps by...

TWiN 23: Peripheral nervous system with Bruce Carter

October 31, 2021 14:32 - 1 hour - 41.4 MB

Bruce Carter joins TWiN to discuss the peripheral nervous system: the development of nerves that convey sensory information like touch from the tips of your toes to the brain, and Schwann cells, which are necessary for ensuring that those sensory signals are sustained as they travel long distances to the brain. Hosts: Vincent Racaniello, Timothy Cheung, and Vivianne Morrison Guest: Bruce Carter Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for...

TWiN 22: It's never lupus

September 29, 2021 20:51 - 1 hour - 39.7 MB

TWiN explains how anti-DNA antibodies present in lupus patients bind to GluN2A-containing NMDA receptors, act as positive allosteric modulators, and impair spatial memory. Hosts: Vincent Racaniello, Ori Lieberman, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Lupus autoantibodies bind GluN2A-containing NMDA receptors (Nat Commun) Timestamps by Jolene. Thanks! Music is by ...

TWiN 21: How do we know if a mouse is hallucinating?

August 24, 2021 04:00 - 1 hour - 51 MB

TWiN explores a study of hallucination-like perception in mice which supports the idea that hallucinations arise as faulty perceptual inferences due to elevated dopamine in the striatum. Hosts: Vincent Racaniello, Ori Lieberman, and Timothy Cheung Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Listener poll - please take it Striatal dopamine and hallucination in mice (Science) Timestamps by Jolene. Thanks! Music is by Ronal...

TWiN 20: Drifting aromas in the brain

July 14, 2021 17:43 - 1 hour - 45.3 MB

While perceptual constancy requires the brain to maintain a stable representation of sensory input, TWiN explores a study showing that odor-evoked responses in the olfactory cortex drift over periods of days to weeks. Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Representational drift in olfactory cortex (Nature) (open preprint) Ed Yong on repr...

TWiN 19: Glia 101

June 21, 2021 15:31 - 1 hour - 42.3 MB

On this episode, Vivianne gives a primer on glial cells, with the goal of thinking about the central nervous system holistically and appreciating the different cell types that contribute to its function. Hosts: Vincent Racaniello, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Music is by Ronald Jenkees Send your neuroscience questions and comments to [email protected]

TWiN 18: Autism and the gut microbiome with Mauro Costa-Mattioli

May 12, 2021 16:15 - 1 hour - 41.2 MB

Mauro Costa-Mattioli joins TWiN to discuss how his laboratory dissects the contribution of host genetics and the microbiome in complex neurodevelopment disorders such as autism spectrum disorders. Hosts: Vincent Racaniello, Ori Lieberman, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Guest: Mauro Costa-Mattioli Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Mauro’s work on TWiM 131 and 193 Separating genetics and mic...

TWiN 17: Worms see the light with Michael Nitabach

April 21, 2021 14:05 - 1 hour - 47.5 MB

Michael Nitabach joins TWiN to discuss the finding that the nematode C. elegans, which do not have eyes, can discriminate between colors to guide foraging decisions and move them away from harmful bacteria that produce a blue-pigment toxin. Hosts: Vincent Racaniello, Ori Lieberman, Jason Shepherd, Timothy Cheung, and Vivianne Morrison Guest: Michael Nitabach Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode C. elegans discriminat...

TWiN 16: Neuronal depolarization with Stefano Brigidi

March 17, 2021 21:50 - 1 hour - 39.5 MB

Stefano joins TWiN to discuss his work on understanding genomic decoding of neuronal depolarization by stimulus-specific transcriptional regulators. Hosts: Ori Lieberman, Jason Shepherd, and Timothy Cheung Guest: Stefano Brigidi Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Genomic decoding of neuronal depolarization (Cell) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees Send your neuroscience questions and com...

TWiN 15: Microbiome and neurodevelopment with Helen Vuong

February 17, 2021 14:57 - 49 minutes - 29 MB

Helen joins TWiN to discuss her work on understanding how the maternal microbiome modulates fetal neurodevelopment in mice. Hosts: Ori Lieberman, Andres Bendesky, Jason Shepherd, and Vincent Racaniello Guest: Helen Vuong Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Maternal microbiome influences fetal neurodevelopment (Nature) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees Send your neuroscience questions and c...

TWiN 14: Reducing Alzheimer-like pathology in mice

January 14, 2021 21:57 - 1 hour - 41.2 MB

Ori, Jason, and Vincent discuss the use of antibodies to neutralize amyloid-β seeds before their deposition becomes detectable in transgenic mice, and the finding that the preclinical phase of Alzheimer‘s disease may be a late manifestation of earlier pathogenic seed formation. Hosts: Ori Lieberman, Jason Shepherd, and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Reducing Alzheimer-like pathology in mice (Na...

TWiN 13: mRNAs for long-term memory

December 15, 2020 19:28 - 1 hour - 39.8 MB

Ori, Jason, Erin, and Vincent dissect a study that utilizes single-cell RNA sequencing to reveal the genes that underlie remote memory storage in the medial prefrontal cortex of the mouse. Hosts: Ori Lieberman, Erin Calipari, Jason Shepherd, and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Transcriptional programs associated with long-term memory (Nature) Timestamps by Jolene. Thanks! Music is by Ronald ...

TWiN 12: A gene for short-term memory

November 11, 2020 15:27 - 1 hour - 42.4 MB

Ori, Jason, and Vincent reveal identification of an orphan receptor that modifies short-term memory in mice, and a mouse model of COVID-19 that includes anosmia or loss of smell. Hosts: Ori Lieberman, Vincent Racaniello, and Jason Shepherd   Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Thalamic orphan receptor in short term memory (Cell) Anosmia in SARS-CoV-2 infected mice (Nature) Letters read on TWiN 12 Timestamps by...

TWiN 11: A dollar per neuron

October 14, 2020 00:58 - 1 hour - 38.6 MB

Maria joins TWiN to explain how single-cell transcriptomics is being used to reveal the evolution of the brain, at a cost of about $1 per neuron. Hosts: Ori Lieberman, Andres Bendesky, and Vincent Racaniello Guest: Maria Tosches Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Single-cell transcriptomics of reptile cortex (Science) Innovations in primate interneurons (Nature) Human versus mouse cortex (Nature) Letters read...

TWiN 10: Remodeling synapses with a cytokine

September 29, 2020 02:03 - 1 hour - 39.2 MB

TWiN explains how a cytokine produced by neurons activates microglia which modify the extracellular matrix and remodel synapses, leading to memory consolidation. Hosts: Ori Lieberman, Andres Bendesky, Erin Calipari, Jason Shepherd and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode IL-33 promotes synaptic plasticity (Cell) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees Send your neuroscience ques...

TWiN 9: COVID-19 neurology with Genna Waldman

August 11, 2020 05:00 - 1 hour - 38.7 MB

Columbia University Chief Neurology Resident Genna Waldman joins TWiN to explains how her department prepared for COVID-19, and the neurological symptoms associated with the disease. Hosts: Ori Lieberman, Andres Bendesky, Jason Shepherd and Vincent Racaniello Guest: Genna Waldman Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Preparing a neurology department for COVID-19 (Neurology) Managing comatose COVID-19 patients (Ann N...

TWiN 8: Replacing lost neurons

July 07, 2020 18:00 - 1 hour - 41.5 MB

TWiN explains how neurological disease in mice can be repaired by using CRISPR/Cas to knock down levels of a single cell protein, which converts astrocytes to neurons. Hosts: Ori Lieberman, Erin Calipari, Jason Shepherd and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Converting glia to neurons (Cell) Reversing Parkinson's disease (Nature) Letters read on TWiN 8 Timestamps by Jolene. Thanks! Intro mu...

TWiN 7: Stress, the good, bad and beautiful

June 13, 2020 13:43 - 1 hour - 48.8 MB

The TWiN team reveals how the nervous system controls hair graying in mice subjected to stress, and adaptive immune responses. Hosts: Ori Lieberman, Jason Shepherd,  Erin Calipari and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for the episode The hair cycle (J Cell Sci) Hyperactivation of sympathetic nerves drives hair greying (Nature) Brain control of humoral immune responses (Nature) Letters read on TWiN 7 Timest...

TWiN 6: Neural control of sexual behavior

May 20, 2020 01:36 - 1 hour - 37.3 MB

Nirao Shah joins TWiN to discuss the work of his laboratory on how our brains generate social interactions that differ between the sexes. Hosts: Ori Lieberman, Andres Bendesky, andJason Shepherd Guest: Nirao Shah Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Nirao Shah laboratory Neural circuit remodeling and sexual behavior (Cell) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees. Send your neuroscience ...

TWiN 5: Anosmia and COVID-19

April 18, 2020 19:40 - 58 minutes - 34.3 MB

Bob Datta joins TWiN to reveal the findings of his laboratory on expression of SARS-CoV-2 entry genes in the olfactory epithelium and the implications for anosmia associated with COVID-19. Hosts: Ori Lieberman, Andres Bendesky, Jason Shepherd, Erin Calipari and Vincent Racaniello Guest: Bob Datta Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Expression of SARS-CoV-2 entry genes in nasal olfactory epithelium (bioRxiv) Expre...

TWiN 4: It's a trap!

January 09, 2020 02:35 - 1 hour - 39.7 MB

Jason visits the TWiN studio to explain Arc Capsid Bearing Any RNAs (ACBARs), virus-like capsids that transfer genetic information between neurons. Hosts: Andres Bendesky, Jason Shepherd, and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Arc is a repurposed retrotransposon gag protein that mediates intercellular RNA transfer (Cell) Drosophila gag-like ARC1 (Cell) Letters read on TWiN #4 Timestamps by J...

TWiN 3: Gambling on dopamine

December 18, 2019 00:30 - 1 hour - 47 MB

Erin and the TWiN team explain how dopamine neurons encode reward probability and uncertainty, and their roles in attention-based learning and risk-taking such as gambling and addiction. Hosts: Ori Lieberman, Erin Calipari,Jason Shepherd, and Vincent Racaniello Click arrow to play Download TWiN 003 (52 MB .mp3, 86 min) Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Dopamine neurons encode reward probability and uncertainty (S...

TWiN 2: Cells that fire together wire together

November 05, 2019 16:33 - 1 hour - 49.6 MB

The TWiN team explain the basic principles of synaptic transmission, and review a classic paper demonstrating that recycling endosomes are important for modifying synaptic strength, which is involved in information storage and processing. Hosts: Ori Lieberman, Andres Bendesky,Jason Shepherd, and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Bendesky lab Recycling Endosomes Supply AMPA Receptors for LTP (Sci...

TWiN 1: The ultimate challenge

October 26, 2019 19:39 - 43 minutes - 25.7 MB

The synaptics launch the first episode of TWiN by revealing their training, research interests, and goals for the podcast. Hosts: Ori Lieberman, Erin Calipari, Jason Shepherd, and Vincent Racaniello Become a patron of TWiN! Links for this episode Lieberman lab Calipari lab Shepherd lab Image credit Intro music is by Ronald Jenkees. Send your neuroscience questions and comments to [email protected]

Twitter Mentions

@jrrmicro 32 Episodes
@jasonsynaptic 29 Episodes
@orilieberman 22 Episodes
@bendesky 8 Episodes
@theerincalipari 6 Episodes