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S3E2: Breaking Barriers in Gene Editing with Harvard Professor David Liu

Theory and Practice

English - March 15, 2022 15:40 - 42 minutes - 38.7 MB - ★★★★★ - 43 ratings
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Gene editing is the process by which alterations are made to DNA.

There are three major challenges: make precise edits at a chosen site, make edits that do not result in subsequent mutations, and have an editing process flexible enough to address the mutations which cause human disease.

This week we talk to Professor David Liu of Harvard University’s Department of Chemistry and Chemical Biology. They discuss the progress that has been made to overcome these challenges, following the development of the base editing and prime editing methods in his lab.

Theory and Practice is a presentation of GV and Google AI.

This season we'll dive deep into the languages of life through explorations of the "dark genome", genome editing, protein folding, the future of aging, and more.

Hosted by Anthony Philippakis (Venture Partner at GV) and Alex Wiltschko (Staff Research Scientist with Google AI), Theory and Practice opens the doors to the cutting edge of biology and computer science through conversations with leaders in the field.