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Beyond penicillin: are new antibiotics for syphilis on the horizon?
STI Podcast
English - March 01, 2024 05:00 - 13 minutes - 12.4 MB - ★★★★ - 3 ratingsScience Health & Fitness Medicine medicine health interviews bmj debates conference roundtable british medical journal Homepage Download Apple Podcasts Google Podcasts Overcast Castro Pocket Casts RSS feed
Today we will focus on the alternative treatments of early Syphilis. Worldwide many of us have experienced a shortage of gold standard treatment benzathine benzylpenicillin injections for syphilis. It is time we look for alternative antibiotic treatments and prevention strategies for syphilis. In conversation with Prof Jeffery Klausner, Professor of Medicine, Infectious Diseases and Public Health at the Keck School of Medicine of the University of Southern California, we will discuss a new study published in the Lancet in 2024. Mitja O. et al compared oral linezolid with benzathine penicillin G for treatment of early syphilis in adults (Trep-AB Study) in Spain, which is a prospective, open-label, non-inferiority, randomised controlled trial.
Acknowledgement for his valuable contributions to the content of the podcast: Dr Oriol Mitjà, Skin Neglected Tropical Diseases and Sexually Transmitted Infections Section, Fundació Lluita Contra les Infeccions, Barcelona, Spain.
Related link:
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00683-7/fulltext