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Is survival predetermined in the critically ill - Mervyn Singer
Coda Change
English - October 24, 2016 20:00 - 20 minutes - 28.6 MB - ★★★★★ - 77 ratingsMedicine Health & Fitness Science coda care covid19 harris icu carley codachange conference coronavirus critical Homepage Download Apple Podcasts Google Podcasts Overcast Castro Pocket Casts RSS feed
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Multiple biomarkers - physiological, biochemical, biological - can prognosticate early in critical illness, even in the ED. This implies the die is already cast (literally as well as figuratively) so we are simply prolonging death is those predetermined to die. We thus need to adopt a completely different strategy for such patients. This also applies to trial design, especially where survival is the endpoint.