๐Ÿ’ก๐Ÿ’ก๐Ÿ’ก ๐ƒ๐ซ.๐˜๐š๐๐š๐ฏ ๐š๐ง๐ ๐ƒ๐ซ.๐‰๐จ๐ฌ๐ž๐ฉ๐ก ๐ฅ๐จ๐จ๐ค ๐ญ๐จ ๐ฌ๐ž๐ญ๐ญ๐ฅ๐ž ๐ญ๐ก๐ž ๐๐ž๐›๐š๐ญ๐ž ๐ข๐ง ๐๐€๐‘๐“ ๐ˆ๐ˆ ๐จ๐Ÿ ๐‘ฐ๐‘ป ๐‘ป๐‘จ๐‘ฒ๐‘ฌ๐‘บ 2 ๐‘ป๐‘ถ ๐‘ป๐’€๐‘ฒ 2.

๐ŸŸข๐‡๐š๐ฏ๐ž ๐ฒ๐จ๐ฎ ๐›๐ž๐ž๐ง ๐ฐ๐จ๐ง๐๐ž๐ซ๐ข๐ง๐  ๐ฐ๐ก๐š๐ญ'๐ฌ ๐ญ๐ก๐ž ๐ซ๐ž๐š๐ฅ ๐๐ข๐Ÿ๐Ÿ๐ž๐ซ๐ž๐ง๐œ๐ž ๐›๐ž๐ญ๐ฐ๐ž๐ž๐ง #๐‰๐€๐Š ๐ข๐ง๐ก๐ข๐›๐ข๐ญ๐ข๐จ๐ง ๐š๐ง๐ #๐“๐˜๐Š-๐Ÿ ๐ข๐ง๐ก๐ข๐›๐ข๐ญ๐ข๐จ๐ง? ๐€๐ซ๐ž๐ง'๐ญ ๐ญ๐ก๐ž๐ฒ ๐ฉ๐š๐ซ๐ญ ๐จ๐Ÿ ๐ญ๐ก๐ž ๐ฌ๐š๐ฆ๐ž ๐ฉ๐š๐ญ๐ก๐ฐ๐š๐ฒ? ย 

๐—ช๐—ฒ๐—น๐—น ๐˜„๐—ฒ ๐˜๐—ฎ๐—ธ๐—ฒ ๐—ฎ ๐—ฑ๐—ฒ๐—ฒ๐—ฝ ๐—ฑ๐—ถ๐˜ƒ๐—ฒ ๐—ถ๐—ป๐˜๐—ผ ๐˜๐—ต๐—ฒ ๐˜€๐—ฎ๐—ณ๐—ฒ๐˜๐˜† ๐—ฐ๐—ผ๐—ป๐˜ƒ๐—ฒ๐—ฟ๐˜€๐—ฎ๐˜๐—ถ๐—ผ๐—ป ๐—ฎ๐—ป๐—ฑ seek clarify for you when it comes to all you need to know about key ๐—ง๐—ฌ๐—ž ๐˜ƒ๐˜€ ๐—๐—”๐—ž ๐˜€๐—ถ๐—ฑ๐—ฒ ๐—ฒ๐—ณ๐—ณ๐—ฒ๐—ฐ๐˜ ๐—ฎ๐—ป๐—ฑ ๐—บ๐—ผ๐—ป๐—ถ๐˜๐—ผ๐—ฟ๐—ถ๐—ป๐—ด ๐—ฐ๐—ผ๐—ป๐˜€๐—ถ๐—ฑ๐—ฒ๐—ฟ๐—ฎ๐˜๐—ถ๐—ผ๐—ป๐˜€.

Our experts ๐—ฎ๐—น๐˜€๐—ผ ๐—ฏ๐—ฟ๐—ฒ๐—ฎ๐—ธ๐—ฑ๐—ผ๐˜„๐—ป ย ๐—ฃ๐—ข๐—˜๐—ง๐—ฌ๐—ž-๐Ÿญ ๐—ฎ๐—ป๐—ฑ ๐—ฃ๐—ข๐—˜๐—ง๐—ฌ๐—ž-๐Ÿฎ ๐—ฎ๐—ป๐—ฑ ๐˜€๐—ต๐—ฎ๐—ฟ๐—ฒ ๐˜๐—ต๐—ฒ๐—ถ๐—ฟ ๐—ฐ๐—ฎ๐—ป๐—ฑ๐—ถ๐—ฑ ๐˜๐—ต๐—ผ๐˜‚๐—ด๐—ต๐˜๐˜€ ๐—ผ๐—ป ๐˜„๐—ต๐—ฒ๐—ฟ๐—ฒ ๐˜๐—ต๐—ฒ๐˜† ๐˜€๐—ฒ๐—ฒ ๐˜๐—ต๐—ฒ ๐—ฝ๐—น๐—ฎ๐—ฐ๐—ฒ ๐—ผ๐—ณ ๐—ฎ ๐—ง๐—ฌ๐—ž-๐Ÿฎ ๐—ถ๐—ป๐—ต๐—ถ๐—ฏ๐—ถ๐˜๐—ผ๐—ฟ, ๐—ถ๐—ป ๐˜๐—ต๐—ฒ๐—ถ๐—ฟ ๐—ฝ๐—ฟ๐—ฎ๐—ฐ๐˜๐—ถ๐—ฐ๐—ฒ๐˜€, ๐—ณ๐—ผ๐—ฟ ๐˜๐—ต๐—ฒ ๐˜๐—ฟ๐—ฒ๐—ฎ๐˜๐—บ๐—ฒ๐—ป๐˜ ๐—ผ๐—ณ ๐—บ๐—ผ๐—ฑ๐—ฒ๐—ฟ๐—ฎ๐˜๐—ฒ ๐˜๐—ผ ๐˜€๐—ฒ๐˜ƒ๐—ฒ๐—ฟ๐—ฒ ๐—ฝ๐˜€๐—ผ๐—ฟ๐—ถ๐—ฎ๐˜€๐—ถ๐˜€.

๐ŸŸข๐˜ผ๐™ง๐™š ๐™ฉ๐™๐™š๐™ง๐™š ๐™–๐™ฃ๐™ฎ ๐™ฅ๐™ง๐™–๐™˜๐™ฉ๐™ž๐™˜๐™–๐™ก ๐™˜๐™ค๐™ฃ๐™จ๐™ž๐™™๐™š๐™ง๐™–๐™ฉ๐™ž๐™ค๐™ฃ๐™จ ๐™›๐™ค๐™ง ๐™ฅ๐™–๐™ฉ๐™ž๐™š๐™ฃ๐™ฉ๐™จ ๐™ฌ๐™๐™ค ๐™–๐™ง๐™š ย ๐™—๐™ž๐™ค๐™ก๐™ค๐™œ๐™ž๐™˜ ๐™ฃ๐™–รฏ๐™ซ๐™š ย ๐™ซ๐™š๐™ง๐™จ๐™ช๐™จ ๐™—๐™ž๐™ค ๐™š๐™ญ๐™ฅ๐™š๐™ง๐™ž๐™š๐™ฃ๐™˜๐™š๐™™?

ย 

๐ŸŸขWhat ๐๐จ๐ž๐ฌ #TYK-2 #inhibition mean for ๐ญ๐ก๐ž #๐ฉ๐ฌ๐จ๐ซ๐ข๐š๐ฌ๐ข๐ฌ ๐ฉ๐š๐ญ๐ข๐ž๐ง๐ญ treatment landscape?

ย 

๐ŸŸขAnd when do I recommend an i๐ง๐ฃ๐ž๐œ๐ญ๐š๐›๐ฅ๐ž ๐ฏ๐ž๐ซ๐ฌ๐ฎ๐ฌ ๐จ๐ซ๐š๐ฅ therapy ๐Ÿ๐จ๐ซ ๐ฆ๐ฒ ๐ฉ๐š๐ญ๐ข๐ž๐ง๐ญ?

ย 

๐ŸŽซ ๐—ง๐—ต๐—ถ๐˜€ ๐—บ๐—ฎ๐—ฟ๐—ธ๐˜€ ๐—ฎ ๐—ณ๐—ถ๐—ฟ๐˜€๐˜ ๐—ณ๐—ผ๐—ฟ ๐˜๐—ต๐—ฒ ๐—ฆ๐—ธ๐—ถ๐—ป ๐—ฎ๐—ป๐—ฑ ๐—๐—ผ๐—ถ๐—ป๐˜๐˜€ ๐—ฃ๐—ผ๐—ฑ๐—ฐ๐—ฎ๐˜€๐˜- ๐˜„๐—ฒ ๐—ต๐—ฎ๐˜ƒ๐—ฒ ๐˜๐˜„๐—ผ ๐—ด๐˜‚๐—ฒ๐˜€๐˜ ๐—ฒ๐˜…๐—ฝ๐—ฒ๐—ฟ๐˜๐˜€ ๐—ผ๐—ป ๐˜๐—ต๐—ฒ ๐˜€๐—ต๐—ผ๐˜„ ๐—ฎ๐˜ ๐˜๐—ต๐—ฒ ๐˜€๐—ฎ๐—บ๐—ฒ ๐˜๐—ถ๐—บ๐—ฒ!

๐—ช๐—ฒ ๐—ฎ๐—ฟ๐—ฒ ๐—ด๐—ผ๐—ถ๐—ป๐—ด ๐˜๐—ผ ๐—น๐—ผ๐—ผ๐—ธ ๐—ฎ๐˜ ๐—ง๐—ฌ๐—ž๐Ÿฎ ๐—ถ๐—ป๐—ต๐—ถ๐—ฏ๐—ถ๐˜๐—ถ๐—ผ๐—ป, ๐—ฎ๐—ป๐—ฑ ๐—ถ๐˜โ€™๐˜€ ๐—ฟ๐—ผ๐—น๐—ฒ ๐—ถ๐—ป ๐˜๐—ต๐—ฒ ๐—ฝ๐˜€๐—ผ๐—ฟ๐—ถ๐—ฎ๐˜€๐—ถ๐˜€ ๐˜๐—ฟ๐—ฒ๐—ฎ๐˜๐—บ๐—ฒ๐—ป๐˜ ๐—น๐—ฎ๐—ป๐—ฑ๐˜€๐—ฐ๐—ฎ๐—ฝ๐—ฒ ๐˜„๐—ถ๐˜๐—ต ๐—ฎ ๐—ณ๐—ผ๐—ฐ๐˜‚๐˜€ ๐—ผ๐—ป ๐—ฎ ๐—ป๐—ฒ๐˜„ ๐—ผ๐—ฟ๐—ฎ๐—น ๐˜€๐—ฒ๐—น๐—ฒ๐—ฐ๐˜๐—ถ๐˜ƒ๐—ฒ ๐—ง๐—ฌ๐—ž๐Ÿฎ ๐—ถ๐—ป๐—ต๐—ถ๐—ฏ๐—ถ๐˜๐—ผ๐—ฟ ๐—ฎ๐—ด๐—ฒ๐—ป๐˜ ๐—ฐ๐—ฎ๐—น๐—น๐—ฒ๐—ฑ ๐—ฑ๐—ฒ๐˜‚๐—ฐ๐—ฟ๐—ฎ๐˜ƒ๐—ฎ๐—ฐ๐—ถ๐˜๐—ถ๐—ป๐—ถ๐—ฏ ๐—ฎ๐—ป๐—ฑ ๐˜„๐—ต๐—ฎ๐˜ ๐˜๐—ต๐—ถ๐˜€ ๐˜€๐—ฒ๐—น๐—ฒ๐—ฐ๐˜๐—ถ๐˜ƒ๐—ฒ๐—น๐˜† ๐—ฐ๐—ผ๐—ป๐—ณ๐—ฒ๐—ฟ๐˜€ ๐—ณ๐—ฟ๐—ผ๐—บ ๐—ฎ ๐˜€๐—ฎ๐—ณ๐—ฒ๐˜๐˜† ๐—ฝ๐—ฟ๐—ผ๐—ณ๐—ถ๐—น๐—ฒ.

๐——๐—ผ๐—ฒ๐˜€ ๐—ถ๐˜ ๐—ง๐—ฌ๐—ž ๐—ฎ๐—น๐—น ๐˜๐—ต๐—ฒ ๐—ฏ๐—ผ๐˜…๐—ฒ๐˜€? ๐—Ÿ๐—ฒ๐˜โ€™๐˜€ ๐—ณ๐—ถ๐—ป๐—ฑ ๐—ผ๐˜‚๐˜!

๐ŸŽ™๏ธ๐ŸŽ™๏ธ๐ŸŽ™๏ธ ๐๐š๐ซ๐ญ II with Dr.Geeta Yadav and Dr.Marissa Joseph!

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Episode Learning Objectives

โ€‹โ€‹Apply current evidence to key efficacy and safety considerations for the oral, selective allosteric tyrosine kinase 2 (TYK2) inhibitor deucravacitinibย ย Describe the ย summary details and potential clinical implications of the ย pivotal trials POETYK-1 and POETYK-2ย Discuss the role of TYK-2 inhibition in moderate to severe psoriasis and the patient journey

ABOUT Dr. Marissa Joseph, MSc, MD, FRCPC ( Pediatrics), FRCPC ( Dermatology)

Toronto, ON

Dr. Marissa Josephย is a board certified Pediatrician and Dermatologist and completed her Pediatric training at the Hospital For Sick Children, followed by her Dermatology residency at the University of Toronto. She completed a MSc in Community Health at the Dalla Lana School of Public Health.

Dr. Joseph is full time academic faculty at the University of Toronto. She has received and has been nominated for teaching awards in both undergraduate and postgraduate medical education.ย 

Dr. Joseph is the Medical Director of the Ricky Kanee Schachter Dermatology Centre at Women's College Hospital. She also works at the Hospital For Sick Children where she manages children with complex dermatologic disease in outpatient and inpatient settings, as well as a pediatric laser treatment program. Dr. Joseph enjoys her diverse practice in general adult, pediatric and surgical dermatology. Her clinical and research interests include inflammatory skin disorders such as psoriasis, atopic dermatitis, and hidradenitis suppurativa; genodermatoses, and equity, diversity and inclusivity.

ย 

ABOUT Dr. Geeta Yadav, MSc, MD, FRCPC ( Pediatrics), FRCPC ( Dermatology)

Toronto, ON

Dr. Geeta Yadav is an expert in both medical and cosmetic dermatology. A second-generation Canadian, her interest in under-serviced communities and treating BIPOC patients was inspired by her childhood travels to India. She holds a masterโ€™s degree in International Health from Johns Hopkins and completed her dermatology training at the University of Toronto, where she still teaches today. Dr. Yadav is a fellow of the Royal College of Physicians and Surgeons, the American Academy of Dermatology, and the European Academy of Dermatology and Venereology.ย 

When sheโ€™s not working, she volunteers as an Alumni Governor at the University of Toronto. She also loves running, dancing, and spending time with her husband and three young children.ย 

ย 

โ–ถ๏ธEpisode supported by an IME Grant from Bristol Myers Squibb


๐Ÿ“ปwww.skinandjoints.ca

โœ‰๏ธ[email protected]