#077 Rewriting genomes to eradicate disease and aging | Dr. George Church
Signal From The Noise: By Podcast Notes
English - August 31, 2022 00:00 - ★★★★★ - 2 ratingsBusiness Health & Fitness podcast notes podcastnotes playlist Homepage Download Apple Podcasts Google Podcasts Overcast Castro Pocket Casts RSS feed
Found My Fitness - Rhonda Patrick: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday
---------
George Church, Ph.D. is a professor of genetics at Harvard Medical School and of health sciences and technology at both Harvard and the Massachusetts Institute of Technology. Dr. Church played an instrumental role in the Human Genome Project and is widely recognized as one of the premier scientists in the fields of gene editing technology and synthetic biology.
In this episode, we discuss:
07:13 - History of the Human Genome Project 15:20 - Manufacturing cell phones (with biology) 17:34 - Genome Project-Write 20:03 - Writing a human Y chromosome (from scratch) 20:48 - What if you could eliminate viral disease? 22:51 - De-extinction and reinstating lost traits and genes 27:06 - The Vertebrate Genomes Project 29:47 - AlphaFold and other AI tools 41:27 - CRISPR vs. Base Editing (emerging tools of genetic engineering) 49:40 - Why multiplex editing will change the world 52:18 - Molecular flight recorder 53:31 - Preventing viral spillover and enhancing livestock 57:40 - PCSK9 gene therapy for cholesterol 01:00:30 - Is aging an evolved program? 01:05:21 - Treating aging with a combination gene treatment 01:09:04 - Does animal research help us understand human aging? 01:11:40 - Human organoids as a model and therapeutic 01:13:34 - Could engineered transplant organs become better than the originals? 01:16:17 - Embryo editing controversy 01:28:41 - Gene editing for space travel 01:30:40 - Can synthetic biology alleviate poverty? 01:34:07 - Is in vitro fertilization and embryo selection practically similar to editing? 01:39:12 - The occasional cost of brilliance 01:45:45 - Eradicating disease with Gene Drive 01:48:55 - Technologies to solve Lyme disease 01:51:57 - Dr. Church's experience with narcolepsy as a bridge to creative insights 02:00:42 - Why George encoded his book in DNAShow notes are available by clicking here
Join over 300,000 people and get the latest distilled information straight to your inbox weekly: https://www.foundmyfitness.com/newsletter
Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A’s with Rhonda and more: https://www.foundmyfitness.com/premium
Learn more about the premium podcast The Aliquot:
https://www.foundmyfitness.com/aliquot