As many as 30% of those who get COVID-19 will continue to have problems in the weeks and months after their infections. Long COVID-19 is defined as a condition in which issues persist for at least three months. But for many, the difficulties last much longer. Extreme fatigue, shortness of breath and what many call brain fog lead the list of long-term complications. Some people also develop heart problems, diabetes, psychiatric issues and trouble with pain in the weeks and months following the initial illness.

In this episode, we speak with Maureen Lyons, MD, an assistant professor of medicine and director of the Care & Recovery After COVID-19 Clinic at the School of Medicine. The clinic was designed specifically to work with so-called long-haulers. She says many of her patients are frustrated at their inability to get back to life as they knew it before COVID-19. We also hear from one of Lyons’ patients, Michelle Wilson. She’s a nurse who became ill with COVID-19 in November 2020 and is still having problems with fatigue, shortness of breath and other difficulties. And we’ll hear from epidemiologist Ziyad Al-Aly, MD, an assistant professor of medicine at Washington University who treats patients in the Veterans Affairs St. Louis Health Care System. He has found that vaccination provides some protection against long COVID-19, but just as vaccinated people still can get breakthrough infections, they also can develop long COVID-19. It’s not as common in vaccinated people, but there’s still a significant risk.

The podcast, “Show Me the Science,” is produced by the Office of Medical Public Affairs at Washington University School of Medicine in St. Louis.