Pioneering neuroscientist Karl Friston joins Tim to talk about a concept he’s developed called the free-energy principle, which may hold the key to advancing the understanding human intelligence as we know it. Karl is a theoretical neuroscientist. He’s an authority on brain imaging. His work has advanced mankind’s understanding of schizophrenia, among other things. At the moment, he’s becoming better known as the originator of the free-energy principle for human action and perception. In this episode, we’ll talk with Karl about that free-energy principle, what it is, what it means and what it can mean for the future.

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I hope you have your coffee and are sitting in a comfortable place, because this conversation is going to introduce you to some entirely new thinking from one of the world’s most unique scientific thinkers, Karl Friston.

Before we get started, you need to know a little about Karl, and you will need an explanation of some of the words we will use here.

Karl Friston is a theoretical neuroscientist. As mentioned, he is an authority on brain imaging. 

1990, he invented something called statistical parametric mapping or (SPM).  invented SPM, a computational technique that helps create brain images in a consistent shape so researchers can make consistent comparisons.

He then invented Voxel-based morphometry or (VBM). An example of this is when he studied London taxi drivers to measure the rear side of the brain’s hippocampus to watch it grow as their knowledge of the streets grew.

After that, he invented something called dynamic causal modeling (DCM) for brain imaging, to determine if people who have severe brain damage or minimally conscious or vegetative.

He is one of the most frequently cited neuroscientists in the world. 

Each one of these inventions centered on schizophrenia research and theoretical studies of value-learning – formulated as the dysconnection hypothesis of schizophrenia. To try to simplify, it’s the hypothesis that when the so-called wiring in your brain isn’t all connecting properly.

Karl currently works on models of functional integration in the human brain and the principles that underlie neuronal interactions.

His main contribution to theoretical neurobiology is a free-energy principle for action and perception (active inference).  That’s what we cover in this episode.

Karl received the first Young Investigators Award in Human Brain Mapping in 1996. He was elected a Fellow of the Academy of Medical Sciences in 1999. Since then, he has received numerous other honors and recognition for his work.
Links

The Genius Neuroscientist Who Might Hold the Key to True AI, Wired
Karl Friston, The Helix Center
Karl Friston and the Free Energy Principle, ExploringYourMind.com

About this Episode’s Guest Karl Friston
Karl Friston is a theoretical neuroscientist and authority on brain imaging. He invented statistical parametric mapping (SPM), voxel-based morphometry (VBM) and dynamic causal modelling (DCM). These contributions were motivated by schizophrenia research and theoretical studies of value-learning, formulated as the dysconnection hypothesis of schizophrenia. Mathematical contributions include variational Laplacian procedures and generalized filtering for hierarchical Bayesian model inversion. Friston currently works on models of functional integration in the human brain and the principles that underlie neuronal interactions. His main contribution to theoretical neurobiology is a free-energy principle for action and perception (active inference).

Friston received the first Young Investigators Award in Human Brain Mapping (1996) and was elected a Fellow of the Academy of Medical Sciences (1999). In 2000 he was President of the international Organization of Human Brain Mapping. In 2003 he was awarded the Minerva Golden Brain Award and was elected a Fellow of th...