She was born to a noble family in Constantinople: her father Anysius Secundus was a senator. She was betrothed to a nobleman who died before they could be wed; resisting all advice to take another husband, Olympias devoted herself entirely to God, giving her large inheritance to the Church and to the poor. She served as a deaconess, first under the Patriarch Nektarios, then under St John Chrysostom. When St John was sent into exile, he advised her to remain in Constantinople, and to continue to serve the Church whatever patriarch took his place. But as soon as the holy hierarch went into exile, a fire destroyed a large part of the City, and St John's enemies accused the holy Olympias of setting the fire. She in turn was exiled to Nikomedia, where she reposed in 408. She left instructions that her body be placed in a coffin and thrown into the sea, to be buried wherever it was cast up. The coffin came to shore at Vrochthoi and was buried there at a church dedicated to the Apostle Thomas. Her relics have continued to be a source of great miracles of healing.
  During his exile, St John Chrysostom wrote a number of letters to St Olympias, seventeen of which have been preserved through the centuries. In one he writes: 'Now I am deeply joyful, not only because you have been delivered from sickness, but even more because you are bearing adversities with such fortitude, calling them trifles — a characteristic of a soul filled with power and abounding in the rich fruits of courage. You are not only enduring misfortune with fortitude, but are making light of it in a seemingly effortless way, rejoicing and triumphing over it — this is a proof of the greatest wisdom.'