![Podcast Notes Playlist: Latest Episodes artwork](https://is5-ssl.mzstatic.com/image/thumb/Podcasts123/v4/d2/66/df/d266dfb1-9614-de6a-4735-72a2ae4cd544/mza_6736385849725781516.png/100x100bb.jpg)
#161 - AMA #23: All Things Nicotine: deep dive into its cognitive and physical benefits, risks, and mechanisms of action
Podcast Notes Playlist: Latest Episodes
English - May 12, 2021 00:00 - 19 minutes - 13.7 MB - ★★★★ - 72 ratingsBusiness Health & Fitness podcast notes podcastnotes playlist Homepage Download Apple Podcasts Google Podcasts Overcast Castro Pocket Casts RSS feed
Drive with Dr. Peter Attia
Podcast Notes Key Takeaways Nicotine is not the same thing as tobacco There are almost 70 carcinogens in the tobacco plant but nicotine is not one of them Nicotine has some potential cognitive benefits Nicotine replacement therapy alone only shows modest efficacy in helping smokers quit Peter Attia chews about 6-8mg of nicotine replacement gum daily and experiences cognitive benefits If you are interested in experimenting with nicotine gum, ease into it as it can cause some nausea at first
Read the full notes @ podcastnotes.org
In this “Ask Me Anything” (AMA) episode, Peter and Bob dive deep into nicotine, a complicated and interesting molecule that has effects on both the brain and the body. They analyze the results of the studies that describe nicotine’s cognitive benefits and potential for inducing weight loss. They talk about a smoking cessation technique called nicotine replacement therapy and give a full breakdown of the various routes of administration, dosing, and safety. Finally, they explore the fascinating and counterintuitive observation that cigarette smokers are less likely to get a severe case of COVID-19.
If you’re not a subscriber and listening on a podcast player, you’ll only be able to hear a preview of the AMA. If you’re a subscriber, you can now listen to this full episode on your private RSS feed or on our website at the AMA #23 show notes page. If you are not a subscriber, you can learn more about the subscriber benefits here.
We discuss:
Untangling nicotine from tobacco [6:00];
Nicotine replacement therapy (NRT) for quitting smoking: products, protocols, and a review of the literature [9:30];
The cognitive benefits of nicotine: Overview of the literature [15:50];
Where nicotine has the most positive impact on cognition [30:30];
Possible mechanisms conferring the benefits of nicotine [37:00];
How modafinil and other nootropics compare to nicotine [47:15];
How nicotine may induce weight loss [54:00];
Relationship between smoking and COVID-19: Analyzing the observation that smoking appears protective against COVID-19 [1:01:45];
Breakdown of the various nicotine replacement therapies: route of administration, dosing, and safety [1:11:30];
Concluding thoughts on nicotine: use cases, addictive properties, and more [1:19:45]; and
More.
Learn more: https://peterattiamd.com/
Show notes page for this episode: https://peterattiamd.com/ama23
Subscribe to receive exclusive subscriber-only content: https://peterattiamd.com/subscribe/
Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/
Connect with Peter on Facebook | Twitter | Instagram.