Orders of Magnitude artwork

Orders of Magnitude

26 episodes - English - Latest episode: 11 months ago -

Orders of Magnitude is the science podcast that explores the world we live in, from the smallest particle to the observable universe!

For our French podcast, go to: https://anchor.fm/atouteechelle

Hosts: Matheus Schultz et Philippe Carle
E-mail : [email protected]
Instagram: @oom.pod

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Episodes

Lisa Hanna - Studying Ants, True Social Organisms

May 23, 2023 19:48 - 54 minutes - 54.3 MB

Lisa Hanna is a Ph.D. student in biology at McGill University who received a prestigious award by the Fonds de Recherche du Québec to study ants and what genetic factors lead to the diverse appearance within the thousands of genetically identical ants of one colony. If you're interested in further information, check out the following links: Dr. Ehab Abouheif's lab website https://www.abouheiflab.org/ Some of Lisa's Publications: https://pubmed.ncbi.nlm.nih.gov/35654666/ https://www.sci...

The Science of Breaking Bad Habits and Being More Productive

June 06, 2022 14:50 - 40 minutes - 37.9 MB

In this episode, Matheus guides us over a small portion of the peer-reviewed literature on the psychology of habits. We discuss some scientifically proven methods to help you prevent bad habits from firing such as environmental design. We also discuss the impact that motivation has on the process of breaking bad habits, and how overachievers become as productive as they are. Cited Literature: "More Than Resisting Temptation: Beneficial Habits Mediate the Relationship Between Self-Control a...

22. What is Alzheimer's Disease?

March 14, 2022 12:00 - 44 minutes - 45.5 MB

This week, we delve into the most common neurodegenerative disease: Alzheimer's. References: Stats on AD and Dementia: Monica Moore, M. S. G., Mirella Díaz-Santos, and Keith Vossel. "Alzheimer’s Association 2021 Facts and Figures Report." Diagnosis of AD using PET scan: Chételat, Gaël, et al. "Amyloid-PET and 18F-FDG-PET in the diagnostic investigation of Alzheimer's disease and other dementias." The Lancet Neurology 19.11 (2020): 951-962. Amyloid Beta, the genetics of AD. Tanzi, Rudolph...

21. A story of science's self-correction

February 28, 2022 15:17 - 34 minutes - 38.7 MB

In today's episode, Philippe tells us about how scientists studying a cell-stress management protein got into a lengthy argument over mistakes found in their published work. This is a great example of how science has the ability to correct its own mistakes over time. References: Yang, Peiguo, et al. "G3BP1 is a tunable switch that triggers phase separation to assemble stress granules." Cell 181.2 (2020): 325-345. Panas, Marc D et al. “Phosphorylation of G3BP1-S149 does not influence stres...

20. The Science of Habit Formation

February 14, 2022 12:00 - 45 minutes - 42.3 MB

At the beginning of every year, people are always talking about their new year's resolution and about adopting healthy habits. But how exactly do you develop new habits? In this episode, Matheus guides us through some of the peer-reviewed literature about habit formation. What are habits? What do you need to form them? And how are scientists studying habits today? Peer-reviewed references: Lally, Phillippa, et al. "How are habits formed: Modelling habit formation in the real world." Europe...

19. Hallmarks of Aging, Part 2

January 31, 2022 12:00 - 24 minutes - 23 MB

Description  Why do we age? This episode explores the molecular processes of aging, and how they are related to the aging we can see. We ask what is aging and how we could slow or reverse it according to the most recent research. Main References and Further Reading: David Sinclair – Lifespan Andrew Steele – Ageless Lopez-Otin et al – The Hallmarks of Aging Borghesan et al – A Senescence-Centric View of Aging: Implications for Longevity and Disease Zhang et al - Senolytic therapy allev...

18. Hallmarks of Aging, Part 1

January 17, 2022 12:00 - 35 minutes - 35.4 MB

Description Why do we age? This episode explores the molecular processes of aging, and how they are related to the aging we can see. We ask what is aging and how we could slow or reverse it according to the most recent research. Main References and Further Reading: David Sinclair – Lifespan Andrew Steele – Ageless Lopez-Otin et al – The Hallmarks of Aging Goodrick et al – Effects of intermittent feeding upon growth and life span in rats Bitto et al – Transient rapamycin treatment can ...

17. Solo - Sleep Paralysis

January 03, 2022 12:00 - 30 minutes - 32.1 MB

Matheus has had several sleep paralysis episodes throughout his life. In this episode, Matheus and Phil discuss the science behind sleep paralysis. What is happening in the brain during a sleep paralysis episode? What are some scientifically proven ways to prevent sleep paralysis? Are there any tricks to snap out of it and to stay calm if it ever happens to you? ***** Hosts: Matheus Schultz et Philippe Carle ***** Contact E-mail:[email protected] Instagram: @oom.pod *****

16. Cara Hawey - Using Stem Cells to Develop Personalized Medicine

December 06, 2021 12:00 - 39 minutes - 38 MB

Cara Hawei is a M.Sc candidate at McGill University researching the application of induced pluripotent stem cells in personalized medicine. Her research focuses on characteristics of dilated cardiomyopathy, a disease of the heart. In this episode we discuss how cells from the blood can be turned back into stem cells so that these new stem cells can be turned into heart muscle cells for Cara's Studies. We also go into further detail on how Cara is developping assays to measure features of di...

16. Cara Hawei - Using Stem Cells to Develop Personalized Medicine

December 06, 2021 12:00 - 39 minutes - 38 MB

Cara Hawei is a M.Sc candidate at McGill University researching the application of induced pluripotent stem cells in personalized medicine. Her research focuses on characteristics of dilated cardiomyopathy, a disease of the heart. In this episode we discuss how cells from the blood can be turned back into stem cells so that these new stem cells can be turned into heart muscle cells for Cara's Studies. We also go into further detail on how Cara is developping assays to measure features of di...

15. Younes Rhazi - UBI and Using Empirical Data in Policy Making

November 22, 2021 12:00 - 44 minutes - 44.2 MB

Younes Rhazi has a bachelors degree in politics and economics. He's now completing a master's degree in international and public affairs at Université de Montréal. In this episode we discuss the pros and cons of universal basic income (UBI). Instead of giving a selling pitch, Younes discusses what we should think about before developing new policies and how science, empirical data, and pilot projects can be used to build confidence in the process of policy making. Ezra Klein's article on t...

14. Dr. Lawrence Kazak - Brown Fat and the Creatine Cycle

November 22, 2021 04:15 - 48 minutes - 45.2 MB

Dr. Lawrence Kazak is an assistant professor in the department of biochemistry at McGill University. He did his PhD at the University of Cambridge and his post-doc at Harvard University, after taking some time to learn the Brazilian martial art capoeira. Today him and his team focus their research on energy metabolism and the control of mitochondrial energetics in fat cells and cancer cells. In this episode we discuss the different types of fat cells in the body, how they produce energy, a...

13. Dr. Julio F. Fiore Jr. – Post-Operative Care.

October 25, 2021 11:00 - 37 minutes - 38.6 MB

Dr. Julio Flavio Fiore is an Assistant professor and the co-director of the department of surgery at McGill University. He did his Ph.D. at the University of Melbourne before establishing himself in Montréal, where he did his post-doctoral studies at McGill. Dr. Fiore is specialized in post-operative recovery after invasive operations such as pulmonary and abdominal surgeries. We discuss the challenges of transforming the subjective experience of patients into measurable values. Then, we ta...

12. Mental Health in Graduate School

October 11, 2021 11:00 - 33 minutes - 35.4 MB

Our friend and former guest Quinn Abram is back to discuss mental health among science graduate students. Our starting point is the UC Berkley study screening students for major depressive disorder and generalized anxiety disorder before and after the COVID19 pandemic. Although the global crisis exacerbated the proportion of students with poor mental health, these measures were already high before and suggest systematic issues. We talk about our personal struggles with mental health, and ac...

11. Jonathan Diamond – Beaver Ecology

September 27, 2021 10:00 - 1 hour - 66 MB

Jonathan Diamond is a Biology Master’s student at McGill University. He is passionate about ecology and strives to understand nature’s interactions as a complex system. His research is focused on studying how the beavers’ skull shape changes across North America as a function of the environment in which this fascinating animal is found. We start by defining ecology as a science and how technology has changed the study of ecosystems. Then, we discussed the use of traditional knowledge in eco...

10. Marie-Luce Fortier & Juliana Lanza – Le Droit et la Recherche #2 – FR

September 20, 2021 10:00 - 50 minutes - 49.8 MB

Cette semaine au podcast, nos invitées sont Juliana Lanza et Marie-Luce Fortier. Marie-Luce est avocate et travaille en tant que conseillère jurdique pour l’Instut de Recherche du Centre Universitaire de Santé Mcgill (IR-CUSM). Juliana est juriste, et œuvre également en tant que conseillère juridique pour le centre recherche du centre hospitalier de l’université de Montréal (CRCHUM). Dans cette deuxième partie du podcast, nous plongeons dans l’aspect industriel de la recherche clinique, par...

9. Julia Fulber – Vaccine Bioreactors – ENG

September 13, 2021 10:00 - 1 hour - 62.4 MB

This week, our guets is Julia Fulber. Julia is a biomedical engineering masters’ student at McGill University. She participates in creating a manufacturing platform to make the production of viral vector vaccines cost-efficient. This involves the optimisation of growing vaccine-producing cells in large scale tanks called bioreactors. Julia walks us through six types of vaccines, highlighting their advantages and challenges. We discuss the process of making her favorite type of vaccine: vira...

8. Marie-Luce Fortier & Juliana Lanza – Le Droit et la Recherche #1 – FR

September 12, 2021 17:19 - 48 minutes - 46.4 MB

Cette semaine au podcast, nos invitées sont Juliana Lanza et Marie-Luce Fortier. Marie-Luce est avocate et travaille en tant que conseillère jurdique pour l’Instut de Recherche du Centre Universitaire de Santé Mcgill (IR-CUSM). Juliana est juriste, et œuvre également en tant que conseillère juridique pour le centre recherche du centre hospitalier de l’université de Montréal (CRCHUM). Marie-Luce et Juliana travaillent d’arrache-pied pour protéger légalement les chercheurs du CRCHUM et de l’I...

7. Pranjal Seth – Microfluidics – ENG

August 30, 2021 09:00 - 40 minutes - 42.2 MB

This week, our guets is Pranjal Seth. Pranjal is a student of biomedical engineering at McGill University and has a background in mechanical engineering. His research pertains to microfluidics, a field that will revolutionize point-of-care medecine in the decades to come. We discussed how the proprieties of fluids change when they only occupy small volumes, and how these features enable new technology to diagnose diseases and empower patients to take their health in their own hands! **** Host...

6. Serge Hamoudou – La Physique des Particules – FR

August 23, 2021 09:00 - 59 minutes - 57 MB

Cette semaine, notre invité est Serge Hamoudou. Serge est étudiant à la maîtrise en physique théorique à l’Université de Montréal. Nous avons discuté des particules qui constituent notre monde. Il nous a résumé la théorie quantique des champs, la meilleure théorie à ce jour pour expliquer le fonctionnement de notre univers. Serge nous a ensuite fait part de quelques phénomènes observables qui ne s’accordent pas parfaitement à cette théorie pourtant robuste. La fréquence de la désintégration...

5. Quinn Abram – The Zika Virus – ENG

August 16, 2021 11:00 - 37 minutes - 38.6 MB

This week, our guest is Quinn Abram. Quinn is a PhD candidate in the department of biochemistry at McGill University. His research seeks to better understand the mechanism whereby the Zika virus can replicate in our cells. Quinn is also involved as co-president of the Biochemistry Graduate Student Society (BGSS). The first half of the podcast is dedicated to building a strong understanding of what viruses are, how they evolve and whether they are evil! We use the example of the Zika virus t...

4. Younes Rhazi – Le Revenu de Base Universel - FR

August 09, 2021 05:00 - 36 minutes - 52.1 MB

Cette semaine au podcast, nous recevons Younes Rhazi. Détentaire d’un baccalauréat en économie et politique, Younes complète présentement sa maîtrise en affaires publiques et internationales à l’Université de Montréal. Il a un intérêt marqué pour les inégalités sociales et les solutions pour remédier à ces dernières. Nous avons discuté des dernières études sur la semaine de quatre jours et sur le revenu minimum garanti. L’économie et la politique sont des sujets complexes, et Younes a su nou...

3. Maya Nikolova – Proteins and Cancer - ENG

August 02, 2021 11:00 - 50 minutes - 60.8 MB

This week on the Podcast, our guest is Maya Nikolova. Maya is currently a molecular biology Master’s student at Université de Montréal. Her research focuses on the proteomics of RAS and RAS-SF, two families of proteins involved in cancer development and progression. Since proteins are a complex topic, we focused the first half of the discussion on explaining what proteins are, and the vast array of things they can do! Then, we explored different facets of Maya’s project, going over a few cu...

3. Maya Nikolova – Fantastic Proteins! (and where to find them) - ENG

August 02, 2021 11:00 - 50 minutes - 60.8 MB

This week on the Podcast, our guest is Maya Nikolova. Maya is currently a molecular biology Master’s student at Université de Montréal. Her research focuses on the proteomics of RAS and RAS-SF, two families of proteins involved in cancer development and progression. Since proteins are a complex topic, we focused the first half of the discussion on explaining what proteins are, and the vast array of things they can do! Then, we explored different facets of Maya’s project, going over a few cu...

2. Simon Goulet - Les Éco-Émotions - FR

July 26, 2021 10:00 - 1 hour - 74.7 MB

Cette semaine au podcast, notre invité est Simon Goulet. Étudiant au doctorat en rechercherche et intervention en psychologie à l'UQÀM, Simon est également un activiste écologiste. Il nous a fait découvrir l'étude des émotions que nous vivons tous lorsque nous sommes mis face à la crise climatique actuelle. Cette discussion est enrichissante car elle nous sort de notre carcan de sciences quantitatives et nous force à contempler la complexité d'étudier qualitativement des émotions, l'une des ...

1. Slater Covenden - Space Exploration and Metal Fuels - ENG

July 19, 2021 12:13 - 1 hour - 121 MB

This week on the Podcast, our guest is Slater Covenden. Slater is starting his Master's degree in mechanical engineering at McGill University. Throughout his undergraduate degree at Concordia University, where he studied aerospace engineering, Slater was part of the rocket division of Space Concordia, acting as the head of research and development in his latter year. Among many other topics, we discussed Slater's experience at Space Concordia, the challenges of going to space, exciting spac...

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