#061 - Dr. Jon Johnson PhD Expert in Chrononutrition from University of Surrey in the UK

Dr Johnston has successfully led projects studying links between circadian, metabolic and nutritional physiology funded by the BBSRC, MRC and Diabetes-UK. His recent research outputs include the analysis of: timed meal effects on the human circadian system; human metabolome rhythms; human skeletal muscle rhythms and time-restricted feeding in humans.

BIO:

Dr Johnston has successfully led projects studying links between circadian, metabolic and nutritional physiology funded by the BBSRC, MRC and Diabetes-UK. His recent research outputs include the analysis of: timed meal effects on the human circadian system (Wehrens et al 2017 Current Biology); human metabolome rhythms (Isherwood et al 2017 FASEB J); human skeletal muscle rhythms (Loizides-Mangoldet al 2017 PNAS; Perrin et al 2018 eLIFE) and time-restricted feeding in humans (Antoni et al 2018 J Nutr Sci). He has also published widely on the topic of hormone rhythmicity. He is a Trustee of the British Society for Neuroendocrinology, and was a core member of BBSRC Committee A. He has a strong track record in public engagement via TV, radio, podcast and written media. He has experience working with the food industry, via consultancy work and research collaborations.

Show Notes:Websites and Social Media Links:

Website – University of Surrey ProfileEmail:  [email protected]

Books Mentioned:

The Circadian Prescription: Get in Step with Your Body's Natural Rhythms

The Four AgreementsRoss O’Carroll-Kelly booksJon’s Book Recommendation(s):

PJ Wodehouse

Articles & Research Mentioned:High Caloric intake at breakfast vs. dinner differentially influences weight loss of overweight and obese women

Meal Timing Regulates the Human Circadian System.

Podcast Mentioned:

ATSW: Episode 210: Greg Potter - Circadian Rhythm masterclassOPEX Podcast: #59: DR. AMY BENDER PHD & SLEEP RESEARCHER

People and Resources mentioned:

Till RoennebergGreg PotterMark KilgallonAmy BenderJames Fitzgerald BatmanSherlock HolmesStarship enterprise

Mstislav RostropovichChiyonofuji MitsuguMartin Luther King JrGenghis KhanFlorence Nightingale

Time-Line:0:00 – 1:47 - Robbie intro’s the show and asks Jon to introduce himself 1:48 – 3:30 - Robbie asks Jon how he got into circadian biology research? 3:31 – 9:45 - Robbie asks Jon to discuss his research around peripheral circadian clock mechanisms in the body

9:46 – 12:47 - Robbie asks Jon what is the relationship between the peripheral and central circadian clocks?12:48 – 16:12 - Robbie asks Jon how much of an impact does shift work have on circadian regulation and how much of detriment the electrical lightbulb has had on human health?16:13 – 21:18 - Robbie asks Jon to share his thoughts on the effects of meal timing on circadian regulation 21:19 – 23:39 - Robbie asks Jon what time of day should humans stop eating and does this time change with the different seasons?

23:40 – 32:47 - Robbie asks Jon about some cofounding factors that may change the metabolic regulation of body across the day?

32:48 – 39:35 - Robbie asks Jon about chronotypes

39:36 – 48:16 - Robbie asks Jon about the circadian timing of medicine and medications48:17 – 51:31 - Robbie asks Jon if melatonin has an antagonistic effect on insulin?51:32 – 56:21 -Robbie asks Jon how applicable are rodent study models when applying their findings to  humans? 56:22 – 1:02:32 - Robbie asks Jon for his thoughts on evolution and meal-timing patterns that have been proposed among hunter-gathers societies 1:02:33 – 1:08:21 - Robbie asks Jon about meal composition and its effects on circadian regulation?1:08:22 – 1:13:29 - Robbie asks Jon about what social changes would he like to see put in place going forward to optimize circadian health?1:13:30 – 1:15:26 - Robbie asks Jon for his top and current book recommendations1:15:27 – 1:16:56 - Robbie asks Jon how he learns

1:16:57 – 1:19:15 - Robbie asks Jon what have been the biggest lessons he has earned so far in his life?

1:19:16 – 1:20:21 - Robbie asks Jon, if he only had 1 year left on planet earth, how would he spend that year and why?

1:20:22 – 1:26:11 - Robbie asks Jon, if he could invite 5 people to dinner, dead or alive, who would he invite and why?

1:26:12 – 1:27:45 - Robbie wraps up the show!