NEJM This Week
240 episodes - English - Latest episode: 14 days ago - ★★★★ - 265 ratingsConcise summaries of everything published in the latest weekly issue of the New England Journal of Medicine (NEJM). NEJM publishes new medical research findings, review articles, and editorial opinion on topics of importance to biomedical science and clinical practice.
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Episodes
NEJM This Week — April 11, 2024
April 10, 2024 14:30 - 36 minutes - 21.5 MBFeaturing articles on alectinib in ALK-positive lung cancer, minimally invasive removal of cerebral hematomas, and CAR T-cell–mediated responses in recurrent glioblastoma; a review article on energy and macronutrients across the life span; a case report of a woman with falls and cognitive decline; a Medicine and Society on money as medicine; and Perspectives on back to the future in Alabama, on the end of B/Yamagata influenza transmission, and on the plight of DEI leaders.
NEJM This Week — April 4, 2024
April 03, 2024 14:30 - 28 minutes - 17 MBFeaturing articles on omitting axillary dissection in breast cancer with sentinel-node metastasis, a trial of lixisenatide in early Parkinson’s disease, nirmatrelvir–ritonavir in outpatients with Covid-19, and hospitalization for chronic kidney disease; a review article on the prevention of cardiovascular disease in type 1 diabetes; a case report of a woman with hyperglycemia refractory to insulin; and a Perspective article on Nazism and the Journal.
NEJM This Week — March 21, 2024
March 20, 2024 14:30 - 30 minutes - 18.2 MBFeaturing articles on autism and prenatal exposure to antiseizure medication, ribociclib plus endocrine therapy in early breast cancer, gene therapy for giant axonal neuropathy, and anti–interleukin-23 in immunodeficiency; a review article on wearable digital health technologies in clinical care; a case report of a man with a fall; and Perspective articles on physicians, spirituality, and compassionate care; on the risks posed by immediate release of test results to patients; and on what one ...
NEJM This Week — March 14, 2024
March 13, 2024 14:30 - 33 minutes - 19.5 MBFeaturing articles on a blood-based test for colorectal cancer screening, a multitarget stool DNA test for colorectal cancer, iptacopan for paroxysmal nocturnal hemoglobinuria, and preterm birth and other outcomes of maternal RSV vaccination; a review article on cerebral cavernous malformations; a case report of a man with cardiac arrest, cardiogenic shock, and hypoxemia; and Perspective articles on vertical integration and American medicine; on aspirin, preeclampsia, and racism; and on a shi...
NEJM This Week — March 7, 2024
March 06, 2024 14:30 - 30 minutes - 18 MBFeaturing articles on an antibody–drug conjugate in untreated urothelial cancer, omalizumab for multiple food allergies, microplastics and nanoplastics in carotid plaque, and benralizumab or mepolizumab for eosinophilic granulomatosis with polyangiitis; a review article on the health effects of endocrine-disrupting chemicals; a Clinical Problem-Solving on peeling and plummeting; a Medicine and Society on beyond moral injury; and a Perspective article on eugenics in the Journal.
NEJM This Week — February 29, 2024
February 28, 2024 14:30 - 31 minutes - 18.6 MBFeaturing articles on a trial of seladelpar in primary biliary cholangitis, a trial of elafibranor in primary biliary cholangitis, cognition and memory after Covid-19, and simple versus radical hysterectomy in women with low-risk cervical cancer; a review article on cardiac rehabilitation; a case report of a woman with alternating sixth cranial nerve palsy; and a Perspective article on practicing medicine in the culture wars. We also describe a new cases series on efforts toward equity in hea...
NEJM This Week — February 22, 2024
February 21, 2024 14:30 - 34 minutes - 40.4 MBFeaturing articles on CD19 CAR T-cell therapy in autoimmune disease, tenecteplase for stroke at 4.5 to 24 hours, biomarker changes in years before Alzheimer’s disease, and a hepcidin mimetic in polycythemia vera; a review article on wearable digital health technologies for epilepsy; a case report of a man with fatigue and night sweats; and Perspective articles on direct-to-consumer platforms for antiobesity medications, on childhood obesity prevention, and on what is a mentor.
NEJM This Week — February 15, 2024
February 14, 2024 14:30 - 32 minutes - 19.3 MBFeaturing articles on frexalimab in multiple sclerosis, e-cigarettes for smoking cessation, cefepime–taniborbactam for complicated UTI, and the treatment of Wolman’s disease in an infant; review articles on treatment-resistant depression in older adults and on Behçet’s syndrome; a case report of a man with fevers; and Perspective articles on ethical issues in safety-net health systems, on secondary cancers after CAR T-cell therapy, and on being worried about white-cell counts.
NEJM This Week — February 8, 2024
February 07, 2024 14:30 - 38 minutes - 22.3 MBFeaturing articles on a phase 3 trial of resmetirom in NASH with liver fibrosis, an interleukin-23–receptor antagonist for plaque psoriasis, the neurovascular complications of F. solani meningitis, and on ocular gene therapy; a review article on coccidioidomycosis and histoplasmosis; a case report of a man with fever and headache after international travel; Medicine and Society articles on a physician attack on the FDA and on being well while doing well; and Perspective articles on the risks ...
NEJM This Week — February 1, 2024
January 31, 2024 14:30 - 30 minutes - 17.7 MBFeaturing articles on an attenuated tetravalent dengue vaccine, skin antisepsis before fracture surgery, N-acetyl-l-leucine in Niemann–Pick Disease type C, in vivo CRISPR-Cas9 treatment for hereditary angioedema, and on seeing medicine more as a job than a calling; a review article on cardiac implantable electronic devices; a Clinical Problem-Solving on flipping the switch; and a Perspective article on explaining health inequities.
NEJM This Week — January 25, 2024
January 24, 2024 14:30 - 32 minutes - 37.3 MBFeaturing articles on daratumumab in myeloma therapy, the early treatment of patent ductus arteriosus with ibuprofen, measurable residual disease in chronic lymphocytic leukemia, hospital prices for physician-administered drugs, and on Asian Americans and racial justice in medicine; a review article on wearable technologies in cardiovascular medicine; a case report of an infant with inconsolable crying and weakness; and Perspective articles on minding the gap, on transforming population healt...
NEJM This Week — January 18, 2024
January 17, 2024 14:30 - 34 minutes - 20.4 MBFeaturing articles on testosterone treatment and fractures in men, long-term resynchronization–defibrillation therapy for heart failure, azithromycin to prevent infant mortality in Burkina Faso, oral simnotrelvir for adult patients with Covid-19, understanding liability risk from health care AI tools, and the rise of house staff unions; a review article on syphilis during pregnancy and congenital syphilis; a case report of a woman with melanoma and fever; and Perspective articles on respondin...
NEJM This Week — January 11, 2024
January 10, 2024 14:30 - 34 minutes - 20.2 MBFeaturing articles on apixaban for stroke prevention in subclinical atrial fibrillation, repotrectinib for ROS1 fusion–positive lung cancer, acoramidis in transthyretin amyloid cardiomyopathy, low-dose calcium supplementation in pregnancy, and the financialization of health in the United States; a review article on peripartum cardiomyopathy; a case report of a woman with bleeding after a snakebite; and Perspective articles on the overdose crisis among U.S. adolescents, on accuracy and equity ...
NEJM This Week — January 4, 2024
January 03, 2024 14:30 - 29 minutes - 17.1 MBFeaturing articles on a drug-eluting scaffold for infrapopliteal disease, a phase 2 trial of sibeprenlimab in IgA nephropathy, liquefied petroleum gas cooking and the effects on severe infant pneumonia and on stunting in infants; a review article on communicating about serious illness and end of life; a Clinical Problem-Solving describing a swell diagnosis; and Perspective articles on the Journal’s historical “Indian Problem”.
NEJM This Week — December 28, 2023
December 27, 2023 14:30 - 34 minutes - 20.3 MBFeaturing articles on dual or single antiplatelet treatment up to 72 hours after stroke, nirsevimab for prevention of RSV hospitalization in infants, sparsentan in focal segmental glomerulosclerosis, transfusion strategy in patients with myocardial infarction and anemia, and the effect of alcohol reduction on cancer incidence; a review article on wearable technology in clinical practice for depressive disorder; a case report of a woman with cough and shortness of breath; and Perspective artic...
NEJM This Week — December 21, 2023
December 20, 2023 14:30 - 34 minutes - 20.1 MBFeaturing articles on percutaneous coronary intervention for stable angina, doxycycline prophylaxis to prevent STIs in women, simvastatin for critically ill patients with Covid-19, and melioidosis in Mississippi; a review article on eye infections; a case report of a woman with chronic diarrhea and skin changes; and Perspective articles on when patients lose decision-making capacity, on silencing the FDA’s voice, and on being hidden behind bars.
NEJM This Week — December 14, 2023
December 13, 2023 14:30 - 31 minutes - 18.7 MBFeaturing articles on semaglutide for prevention of cardiovascular events, an mRNA-based RSV PreF vaccine in older adults, recombinant or standard-dose influenza vaccine, tebentafusp in metastatic uveal melanoma, and on the predominance of Medicare Advantage; a review article on cannabis-related disorders and toxic effects; a case report of a woman with abnormal movements and confusion; and Perspective articles on medicine’s lessons for AI regulation, on “unwinding” continuous Medicaid covera...
NEJM This Week — December 7, 2023
December 06, 2023 14:30 - 30 minutes - 17.9 MBFeaturing articles on sotorasib plus panitumumab in KRAS-mutated colorectal cancer, baricitinib and β-cells in new-onset type 1 diabetes, teplizumab in youth with new-onset type 1 diabetes, and mirvetuximab soravtansine in FRα-positive, platinum- resistant ovarian cancer; a review article on waterborne disease sensitivity to climate change; a Clinical Problem-Solving on collecting puzzle pieces; and we introduce a new series on Historical Injustices in Medicine and the Journal with our first ...
NEJM This Week — November 30, 2023
November 29, 2023 14:30 - 32 minutes - 19.1 MBFeaturing articles on levothyroxine for unstable brain-dead heart donors, amivantamab in lung cancer with EGFR exon 20 insertions, amikacin to prevent ventilator-associated pneumonia, and tarlatamab in small-cell lung cancer, a new series on wearable digital health technology with a review article on digital technology for diabetes; a case report of a man with sickle cell disease and right hip pain; and Perspectives on coverage for emerging technologies, on methadone clinic engagement and can...
NEJM This Week — November 23, 2023
November 22, 2023 14:30 - 31 minutes - 18.2 MBFeaturing articles on osimertinib and chemotherapy in EGFR-mutated non–small-cell lung cancer, transcatheter aortic-valve replacement in low-risk patients at five years, erdafitinib or chemotherapy in urothelial carcinoma, and liver transplantation for Mahvash disease; a review article on postmenopausal osteoporosis; a case report of a man with diabetes and kidney cysts; and Perspectives on opening the door to international medical graduates, on community-engaged research, and on woman, life,...
NEJM This Week — November 16, 2023
November 15, 2023 14:30 - 33 minutes - 19.4 MBFeaturing articles on selpercatinib in RET fusion–positive NSCLC, selpercatinib in RET-mutant medullary thyroid cancer, gantenerumab in early Alzheimer’s disease, and stimulated copeptin to diagnose AVP deficiency; a review article on liver transplantation; a case report of a woman with waxing and waning pulmonary nodules; and Perspective articles on Rift Valley fever, on implanting a recalled device, and on biopsies from healthy volunteers in precision medicine.
NEJM This Week — November 9, 2023
November 08, 2023 14:30 - 35 minutes - 20.6 MBFeaturing articles on genetic variation and life span in Iceland, botulinum toxin for head tremor, decolonization in nursing homes to prevent infection, nivolumab plus chemotherapy in urothelial carcinoma, pembrolizumab in pregnancy, and on after affirmative action; a review article on catatonia; a case report of a woman with loss of consciousness and thrombocytopenia; and Perspective articles on how the FDA should evaluate psychedelic medicine, on federal oversight of laboratory-developed te...
NEJM This Week — November 2, 2023
November 01, 2023 14:30 - 30 minutes - 17.6 MBFeaturing articles on thalidomide for recurrent bleeding due to small-intestinal angiodysplasia, pulsed field ablation for paroxysmal atrial fibrillation, perioperative chemoimmunotherapy in lung cancer, and corin and cardiac phenotypes; a review article on cystic fibrosis; a Clinical Problem-Solving on being encased in peril; and Perspective articles on minimum-staffing rules for U.S. nursing homes, on reforming pharmacy benefit managers, on scaling up point-of-care fentanyl testing, and on ...
NEJM This Week — October 26, 2023
October 25, 2023 14:30 - 31 minutes - 18.3 MBFeaturing articles on patisiran for transthyretin cardiac amyloidosis, automated insulin delivery in pregnancy complicated by diabetes, nemolizumab for prurigo nodularis, convalescent plasma for Covid-19–induced ARDS, and debt collection in American medicine; a case report of a man with shortness of breath; and Perspective articles on climate, health, and equity under the Farm Bill; on indigenous health perspectives on the Lāhainā fires, on whether price negotiations delay cancer-drug launche...
NEJM This Week — October 19, 2023
October 18, 2023 14:30 - 32 minutes - 19 MBFeaturing articles on on enzalutamide and leuprolide in prostate cancer, optical coherence tomography (OCT)–guided versus angiography-guided PCI, vancomycin and cefazolin prophylaxis in arthroplasty, and on OCT and eye care; a review article on the syndrome of inappropriate antidiuresis; a case report of a woman with recurrent hemorrhagic pericardial effusion; and Perspective articles on Yellow Jack’s potential return to the American South; on wedding websites, free speech, and adverse drug e...
NEJM This Week — October 12, 2023
October 11, 2023 14:30 - 33 minutes - 19.6 MBFeaturing articles on dexamethasone for TB meningitis in HIV-positive adults, the timing of complete revascularization after myocardial infarction, catheter ablation for advanced heart failure and AFib, ceftobiprole for Staph. aureus bacteremia, and on AlphaFold being recognized through a Lasker Award; a review article on Shiga toxin–producing E. coli and the hemolytic–uremic syndrome; a case report of a man with involuntary movements and unresponsiveness; and Perspective articles on whether ...
NEJM This Week — October 5, 2023
October 04, 2023 14:30 - 33 minutes - 19.4 MBFeaturing articles on sarilumab for relapsing polymyalgia rheumatica; modifiable risk factors, cardiovascular disease, and mortality; extracorporeal life support in cardiogenic shock; and esketamine vs. quetiapine for treatment-resistant depression; a review article on stem-cell aging and precancer evolution; a Clinical Problem-Solving on digging into the histology; and Perspective articles on preventing heat-related illness among outdoor workers, on countering the health disinformation machi...
NEJM This Week — September 28, 2023
September 27, 2023 14:30 - 35 minutes - 20.7 MBFeaturing articles on anticoagulation and atrial high-rate episodes, tight blood-glucose control in patients in the ICU, increasing artemisinin-resistant malaria in Eritrea, the death of a patient after high-dose gene therapy, and on antiracist documentation practices; a review article on where medical statistics meets AI; a case report of a woman with confusion; and Perspective articles on affirmative action, population health, and hope; on threatening the global AIDS response; and on swimming.
NEJM This Week — September 21, 2023
September 20, 2023 14:30 - 27 minutes - 16.5 MBFeaturing articles on semaglutide for heart failure in patients with obesity, inhaled fluticasone furoate for treatment of Covid-19, a trial of solanezumab in preclinical Alzheimer’s disease, and targeting the BRAF pathway in pediatric glioma; a review article on the prevention of central line–associated bloodstream infections; a case report of a woman with abdominal distention and acute kidney injury; and Perspective articles on the new USPSTF mammography recommendations, on the ethics of ab...
NEJM This Week — September 14, 2023
September 13, 2023 14:30 - 32 minutes - 19 MBFeaturing articles on ferric carboxymaltose for heart failure with iron deficiency, antibiotic prophylaxis in infants with vesicoureteral reflux, the FGF21 analogue pegozafermin in NASH, and mezigdomide in relapsed and refractory multiple myeloma; a review article on asthma in adults; a case report of a man with a rash; and Perspective articles on a doctrine in name only, on the accelerated approval program for cancer drugs, and on a shared mission.
NEJM This Week — September 7, 2023
September 06, 2023 14:30 - 31 minutes - 18.4 MBFeaturing articles on the GLP-1 receptor agonist orforglipron for obesity, PCI in older patients with myocardial infarction, DNA editing in T-cell acute lymphoblastic leukemia, and atezolizumab in alveolar soft part sarcoma; a review article on Wilson’s disease; a Clinical Problem-Solving on how it’s all in the timing; and Perspective articles on NIH policy changes regarding international research collaborations, on alleviating medical debt in the United States, and on mass masking without ma...
NEJM This Week — August 31, 2023
August 30, 2023 14:30 - 34 minutes - 20.2 MBFeaturing articles on concizumab in hemophilia A or B with inhibitors, the timing of primary surgery for cleft palate, improved mass screening for nasopharyngeal carcinoma, gene editing for sickle cell disease, and on artificial sweeteners; a review article on informative artifacts in AI-assisted health care; a case report of a woman with celiac disease and upper gastrointestinal bleeding; and Perspective articles on Project NextGen, on gerineuropalliative care for patients with dementia, and...
NEJM This Week — August 24, 2023
August 23, 2023 14:30 - 30 minutes - 18 MBFeaturing articles on preventing cardiovascular disease in HIV infection, the effect of hemodiafiltration or hemodialysis on mortality in kidney failure, a new KRAS G12C inhibitor in solid tumors, and on partial artemisinin resistance in malaria parasites; a review article on protein-losing enteropathy; a case report of a girl with abdominal pain and an ovarian mass; and Perspective articles on the Supreme Court and diversity in medicine, on outbreaks in U.S. migrant detention centers, on tur...
NEJM This Week — August 17, 2023
August 16, 2023 14:30 - 35 minutes - 20.7 MBFeaturing articles on vorasidenib for IDH-mutant low-grade glioma; a trial of dietary intervention for cognitive decline; omitting radiotherapy after breast-conserving surgery in luminal A breast cancer; gene therapy for the Crigler–Najjar syndrome; and on abortion counseling, liability, and the First Amendment; a review article on community-acquired pneumonia; a case report of a man with fever and foot pain; and Perspective articles on prioritizing mental health in the HIV/ AIDS response in ...
NEJM This Week — August 10, 2023
August 09, 2023 14:30 - 33 minutes - 38.8 MBFeaturing articles on neoadjuvant therapy for lung cancer, a phase 2 trial of retatrutide for obesity, systemic inflammation and normocytic anemia in DOCK11 deficiency, and on the social determinants of health; a review article on thrombocytopenia in pregnant women; a case report of a man with a pulmonary nodule; and Perspective articles on over-the-counter access to HIV preexposure prophylaxis, on preparing physicians for the clinical algorithm era, and on reading Kafka in the hospital cafet...
NEJM This Week — August 3, 2023
August 02, 2023 14:30 - 35 minutes - 21 MBFeaturing articles on a novel sodium channel blocker to treat acute pain, the effects of adult thymectomy, video vs. direct laryngoscopy for tracheal intubation, and on antidepressant maintenance in bipolar I depression; a review article on the neurologic consequences of preterm birth; a Clinical Problem-Solving on a race to the finish; and Perspective articles on AI and medical education, on expanding access to health care for DACA recipients, and on the freedom cure.
NEJM This Week — July 27, 2023
July 26, 2023 14:30 - 31 minutes - 18.2 MBFeaturing articles on weekly insulin icodec or daily glargine in type 2 diabetes, an orexin receptor 2 agonist in narcolepsy, neoadjuvant therapy for rectal cancer, and cilta-cel in lenalidomide-refractory multiple myeloma; a review article on artificial intelligence in U.S. health care delivery; a case report of a young man with progressive dyspnea; and Perspective articles on a critical opportunity to improve public health data, on the future of prior-authorization reform, and on curiosity ...
NEJM This Week — July 20, 2023
July 19, 2023 14:30 - 31 minutes - 18.6 MBFeaturing articles on dupilumab for COPD with type 2 inflammation, a maternal group B streptococcus vaccine, an RNA interference therapeutic agent for hypertension, and the antibody NI006 for depletion of cardiac amyloid; a review article on obesity in adolescents; a case report of a woman with hypotension and electrocardiographic changes; and Perspective articles on closing the vaccine-coverage gap for adults, on whether nonprofit hospitals deserve their tax exemption, on pursuing gender equ...
NEJM This Week — July 13, 2023
July 12, 2023 14:30 - 36 minutes - 21.1 MBFeaturing articles on the cardiovascular safety of testosterone therapy, targeting BRAF in papillary craniopharyngioma, prehospital tranexamic acid for severe trauma, survival with CAR T cells in relapsed lymphoma, and osimertinib in EGFR-mutated non–small-cell lung cancer; a review article on cutaneous electroanalgesia for pain relief; a case report of a man with eyelid swelling; and Perspective articles on Medicare’s plan for drug-price negotiation, on the National Health Service in the Uni...
NEJM This Week — July 6, 2023
July 05, 2023 14:30 - 36 minutes - 21.6 MBFeaturing articles on the early detection and treatment of postpartum hemorrhage, a randomized trial of bulevirtide in chronic hepatitis D, pirtobrutinib in chronic lymphocytic leukemia, and mild hypercapnia after out-of-hospital cardiac arrest; a review article on hepatitis D virus infection; a Clinical Problem-Solving describing a bumpy road to diagnosis; and Perspective articles on PEPFAR at 20, on strategic masking, and on armed-assailant preparedness drills in schools.
NEJM This Week — June 29, 2023
June 28, 2023 14:30 - 30 minutes - 17.7 MBFeaturing articles on anticoagulation for stroke and atrial fibrillation, familial clonal hematopoiesis and long telomeres, JYNNEOS vaccine effectiveness against mpox, and mirikizumab for ulcerative colitis; a review article on artificial intelligence in molecular medicine; a case report of a man with a solitary fibrous tumor and hypoglycemia; and Perspective articles on sharing pathogen genomic sequence data; on hydrofluorocarbons, climate, and health; and on patient-assistance programs, kic...
NEJM This Week — June 22, 2023
June 21, 2023 14:30 - 31 minutes - 18.2 MBFeaturing articles on ketamine versus ECT in treatment-resistant depression; the Eat, Sleep, Console method for neonatal opioid withdrawal; prophylaxis against graft-versus-host disease; dolutegravir as second-line HIV infection treatment; and a dual-chamber leadless pacemaker; a review article on lateral epicondylitis; a case report of a man with left foot drop; and Perspective articles on the origins of Covid-19, on equity and obesity treatment, and on the ellipsis.
NEJM This Week — June 15, 2023
June 14, 2023 14:30 - 30 minutes - 17.7 MBFeaturing articles on craniectomy vs. craniotomy for acute subdural hematoma, glucocorticoids for chronic subdural hematoma, a cause of disabling pansclerotic morphea, and antagonistic leptin variants and the treatment of obesity; a review article on squamous-cell carcinoma; a case report of a woman with dyspnea and tachypnea; and Perspective articles on xylazine, on the Jackson water crisis, and on testing for fentanyl.
NEJM This Week — June 8, 2023
June 07, 2023 14:30 - 29 minutes - 17.5 MBFeaturing articles on outcomes with donor hearts after circulatory death, treatment of gestational diabetes in early pregnancy, and anti-PD1 therapy plus chemotherapy in endometrial cancer; a review article on posterior reversible encephalopathy syndrome; a case report of a woman with fatigue and eosinophilia; and Perspective articles on moving toward comprehensive care for long Covid, on workplace accommodations for long Covid, and on over-the-counter hearing aids.
NEJM This Week — June 1, 2023
May 31, 2023 14:30 - 29 minutes - 17.3 MBFeaturing articles on tirofiban for stroke, a five-year follow-up after transcatheter repair of secondary mitral regurgitation, diagnostic imaging for pediatric forearm fractures, and AKT pathway inhibition in HR-positive breast cancer; a review article on adipose tissue and insulin sensitivity; a Clinical Problem-Solving describing a wrong turn; and Perspective articles on ensuring a reliable platelet supply, on supporting robust teamwork, and on an invitation to lunch.
NEJM This Week — May 25, 2023
May 24, 2023 14:30 - 33 minutes - 19.6 MBFeaturing articles on hydrocortisone in severe community-acquired pneumonia, a meningococcal vaccine in Mali and Gambia, platelet transfusion before CVC placement in patients with thrombocytopenia, and upadacitinib therapy for Crohn’s disease; a review article on using AI to interpret medical images; a case report of a boy with depression and hypotension; and Perspective articles on U.S. law and discrimination in health care, on enhancing regulations to reduce exposure to PFAS, and on public ...
NEJM This Week — May 18, 2023
May 17, 2023 14:30 - 34 minutes - 19.7 MBFeaturing articles on transcatheter repair for tricuspid regurgitation, rifapentine in household contacts of persons with leprosy, peresolimab for rheumatoid arthritis, and emodepside for T. trichiura and hookworm infections; a review article on tricuspid regurgitation; a case report of a man with paresthesia of the arms and legs; and Perspective articles on advancing community living for people with disabilities, on essential steps for abolishing disability injustice, and on the thin pane.
NEJM This Week — May 11, 2023
May 10, 2023 14:30 - 32 minutes - 19 MBFeaturing articles on anti-CD20 antibodies and venetoclax in chronic lymphocytic leukemia, epicutaneous immunotherapy in toddlers with peanut allergy, cabozantinib in advanced renal-cell carcinoma, and racial inequality in the receipt of medications for opioid use disorder; a review article on HPV vaccination; a case report of a man with redness of the right eye; and Perspective articles on addressing serious illness care in Medicare Advantage, on corporate citizenship and institutional respo...
NEJM This Week — May 4, 2023
May 03, 2023 14:30 - 33 minutes - 19.2 MBFeaturing articles on interrupting therapy to attempt pregnancy after breast cancer, trifluridine–tipiracil and bevacizumab in colorectal cancer, imaging- or angiography-guided PCI for complex lesions, and idiopathic CD4 lymphocytopenia; a review article on neonatal seizures; a Clinical Problem-Solving describing a diagnostic sequence; and Perspective articles on combating West Nile virus disease, on falling insulin prices, on next steps in policy reforms to address the overdose crisis, and o...
NEJM This Week — April 27, 2023
April 26, 2023 14:30 - 29 minutes - 16.9 MBFeaturing articles on a 15-year follow-up of prostate cancer therapies, on deciphering developmental disorders, blinatumomab in infant acute lymphoblastic leukemia, and a BCG vaccination against Covid-19; a review article on advances in AI for infectious-disease surveillance; a case report of a woman with abdominal pain and jerking movements; and Perspective articles on access to biomedical innovation, on helping people stop smoking, and on racial affinity group caucusing in medical education.