Refresh Your Cells?

Ira Pastor, ideaXme longevity and ageing ambassador and founder of Bioquark interviews Matthew Roberts PhD, MBA, Chief Scientific Officer and Senior Vice President of ChromaDex. They discuss new innovative research into the restoration and repair of metabolic homeostasis, "refreshing your cells".

Ira Pastor comments:

There has been quite a bit of activity over the past few years in one niche of the aging biotechnology community that has to do with damage repair, and when we mention “damage”, we refer to the range of molecular damage, cellular damage, tissue and organ damage that leads to downstream pathology, degeneration, suffering and death.

There has been quite a bit of activity in the area of devRhat upstream from these damage events sits a complex metabolic architecture, across our 50 trillion cells, that quietly chugs along behind the scenes of our daily lives, producing more damage; the so called “side effects of living.”

These processes involve metabolic dynamics that include nutrient signaling, intercellular, paracrine communication, and mitochondrial dynamics, just to name a few; all of which due to time and randomness, start to go awry.

So, today’s guest, who is going to take us further along this theme, and discuss important bio-product intervention research that help restore and rebalance this loss of metabolic homeostasis is Dr. Matthew Roberts, Chief Scientific Officer and Senior Vice President of Innovation of the ChromaDex Corporation.

Matt has BS in molecular biology from Purdue, a PhD in toxicology from Cornell, and an MBA from Washington University’s Olin Business School. He has spent over 25 years in cross-functional roles across multiple industry segments (food, pet care, pharma, consumer and functional nutrition) at such market leaders as Nestle, Purina, Abbott, Nature’s Bounty, Pharmavite, and now at ChromaDex working in a very “hot” area of nicotinamide adenine dinucleotide (or NAD) bio-products.

He’s member of the Cold Spring Harbor Laboratory Corporate Advisory Board. Matt has also served advisory roles in various investment, venture capital firms.

Today, Matt talks with me:

-About his background, how you he got interested in science, molecular biology / toxicology, and eventually how he transitioned into executive roles at the epicenter of science and business in some of the largest global food, pharma, nutritional organizations.

-His perspectives on the global bio-nutrition industry and how he sees the whole space maturing.

-About nicotinamide adenine dinucleotide (or NAD) and a related metabolite, nicotinamide riboside (NR) and how they were developed and where he sees future development, exploration of their functional properties and new clinical indications.

Research papers here: https://www.ncbi.nlm.nih.gov/m/pubmed/?term=NAD+nicotinamide

-The recent publication last week in the Journal of the American College of Cardiology, or JACC, about NAD, NR research and potential significance for cardiovascular health.

-Looking forward 20 years what he sees as certain types of products and product classes that are most exciting and where he sees the bio-nutrition space in going out to 2040.

Credits: Ira Pastor interview video, text and audio interview.

All relevant links for the interview will be on ideaXme's blog www.radioideaxme.com from 20 May 2019.

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