Molecules, microbes and multiomics
28 episodes - English - Latest episode: 8 months ago - ★★★★★ - 3 ratingsMolecules, microbes and multiomics is DNA Genotek's podcast, featuring experts in all areas of the genomics, microbiome and multiomics space. To learn more about any of these emerging areas of science, tune in.
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Episodes
Breaking new ground in PTSD research: Insights from The Consortium for Post-Traumatic Stress Disorders
September 01, 2023 19:56 - 45 minutes - 41.7 MBIn this episode, Ajin Abraham (Strategic Marketing Manager, Genomics) and Sanna Abbasi, Ph.D. (Scientific Writer/Content Specialist) interview a group of leaders in the Psychiatric Genomics Consortium for Post-Traumatic Stress Disorders (PGC-PTSD). The purpose of the Psychiatric Genomics Consortium is to unite investigators around the world to conduct meta- and mega-analyses of genome-wide data for psychiatric disorders. We talk about the mission of the PGC-PTSD workgroup, how genomics is c...
Expand into multi-omics: DNA Genotek and Diversigen 2021 grant program winner
May 23, 2023 20:31 - 17 minutes - 23.8 MBIn this podcast, we interview Dr. Jonas Schluter, Assistant Professor from the Department of Microbiology at the Grossman School of Medicine at NYU Langone Health and a winner of the DNA Genotek and Diversigen 2021 Expand into Multi-omics grant, discuss his research.
Phosphorus: Stretching the Capabilities of Clinical-Grade Genetic Testing
November 04, 2021 13:00 - 19 minutes - 27.5 MBWe invited Alexander Bisignano, CEO of Phosphorus, to tell us more about his company’s application of genetic testing and to share what is in store for them in the future.
Forensic science and the oral microbiome
August 20, 2021 14:46 - 12 minutes - 17.3 MBCan the oral microbiome help law enforcement link suspects to crime scenes or evidence? In this episode of Molecules, Microbes and Multiomics Heloise Breton PhD, a product manager at DNA Genotek with a background in forensic science, and Megan Anderson, a recent graduate from Rock Canyon High School, chatted with us about Megan’s project on the oral microbiome in collaboration with the team of scientists at Diversigen.
Urine the 'golden sample': Why is urine so exciting in cervical cancer prevention?
April 21, 2021 19:24 - 22 minutes - 31.6 MBWe recently had the opportunity to interview Dr. Severien Van Keer, a post-doc researcher at the VAXINFECTIO research group, at the University of Antwerp. Her research primarily focuses on Human Papillomavirus (HPV) detection in first-void urine, and the potential of urine as a sample type for cervical cancer screening. Her research also includes Novosanis' Colli-Pee®, a first-void urine collection device.
Oral microbiome: The key to better therapeutics
April 15, 2021 13:43 - 24 minutes - 33.4 MBOne new start-up microbiology company, Brick Built, is focused on the potential of the human oral microbiome. Our two microbiome product managers at DNA Genotek, Dr. Heloise Breton, and Laura Cunningham, had the pleasure of speaking with Brick Built Therapeutics co-founder Dr. Brian Klein about the role and future potentials of the oral microbiome in our health and biotech industry.
Leaving no microbe behind: Shoreline Biome’s easy solutions for microbiome NGS
February 18, 2021 18:00 - 11 minutes - 16.4 MBShoreline Biome is a microbiome-focused company that provides simple solutions for microbiome next-generation sequencing. They develop tools and reagents to support end-to-end microbiome analysis. We talk about the amazing work of the team at Shoreline Biome and had the pleasure to interview their Director of R&D, Dawn Gratalo.
Behind the data: an interview with Dr. Dan Knights
February 09, 2021 19:14 - 33 minutes - 46.2 MBIn this interview with Dr. Dan Knights, Senior Scientific Advisor of Diversigen, learn about the future of data generation from microbiome samples. Dr. Knights discusses how he started in microbiome and bioinformatics research, ways to increase the power of microbiome studies, and different signals within the microbiome.
RNA breakthroughs in autism, concussions, and COVID-19
January 07, 2021 19:12 - 21 minutes - 29 MBIn this podcast, we explore how DNA Genotek and Quadrant Biosciences have been working together to support advancements in various diseases via RNA research and collection. Together, they've created RNA tests for early detection of autism spectrum disorder, Parkinson’s disease, traumatic brain injury, and COVID-19.
Probiotics, a possible solution to COVID-19 transmission?
December 16, 2020 19:24 - 22 minutes - 30.9 MBWe interview a team from Duke University in Durham, North Carolina, who are exploring the impact of probiotics in COVID-19 transmission with a new clinical trial: Probiotics To Eliminate COVID-19 Transmission in Exposed Household Contacts (PROTECT-EHC).
Personalized skin care: the beauty industry diving into the microbiome
November 12, 2020 16:43 - 28 minutes - 39.4 MBThe interest in human microbiome has widened from the gut to other parts of the human body, like skin. One company saw an opportunity to combine the science of the human skin microbiome, makeup and skincare. In this episode of Molecules, Microbes, and Multiomics, we interview the co-founders of Pure Culture Beauty Joy Chen, former CEO of Yes To and H2O+ Beauty, and Victor Casale, former chief chemist of MAC Cosmetics and co-founder of Cover FX.
Challenges and solutions for global shortages of materials for COVID-19 testing
October 27, 2020 17:00 - 11 minutes - 15.7 MBWhen the pandemic hit, the demand for COVID-19 testing drastically increased, resulting in shortages of COVID-19 sampling and laboratory supplies and impacting the number of tests that could be performed. When we confirmed that our collection devices could stabilize, and inactivate the SARS-CoV-2 virus, we knew we could help. In this podcast we discuss the challenges and solutions for global shortages of materials for COVID-19 testing featuring DNA Genotek's COVID-19 experts.
Urine as a game-changing liquid biopsy in cancer biomarker detection
October 21, 2020 15:09 - 16 minutes - 22.9 MBWe recently had the opportunity to interview Professor Patrick Pauwels, head of the laboratory of molecular pathology and co-director of CORE, a joint oncology research platform with the University of Antwerp. This podcast discusses the potential of liquid biopsies, such as urine in the field of cancer research especially when tissue is an issue. It also highlights URODETECT, a collaborative project between CORE and Novosanis, which focuses on investigating urinary biomarkers for prostate ...
Metabolomics and the microbiome
August 28, 2020 12:30 - 22 minutes - 30.2 MBThe question of “What is Metabolomics” has been buzzing around the scientific community. With the advances of new technology, a gateway to studying metabolomics has been opened. Over recent years, microbiome researchers have begun to incorporate metabolomics, the “missing piece of the puzzle”, as part of their multiomics studies To understand that missing piece more clearly and what it could mean for the future of multiomics, we feature two experts from DNA Genotek, Dr. Heloise Breton, Pr...
Solving the mysteries of your pet’s gut health
August 13, 2020 18:00 - 29 minutes - 40.4 MBNom Nom is not your average pet food company. In addition to delivering fresh, healthy meals for cats and dogs created by a team of veterinary nutritionists, they use gut microbiome samples submitted by their customers to study the link between nutrition and pet health. Nom Nom partners with Diversigen to analyze these samples and provide the accurate sequencing and bioinformatics analysis the Nom Nom scientists require to learn about the impact of nutrition on pet health. We speak with Dr...
Detection and full genotyping of Human Papillomavirus (HPV) in first-void urine
June 17, 2020 19:18 - 24 minutes - 34 MBWe recently had the opportunity to interview Rebecca Millecamps, a Marketing Manager at Fujirebio, a global leader in the field of in vitro diagnostics (IVD). In 2019, Novosanis and Fujirebio, signed a worldwide, non-exclusive agreement for the distribution of Colli-Pee®, Novosanis’ urine collection device for use with Fujirebio’s INNO-LiPA HPV genotyping Extra II assay. This partnership enables detection and full genotyping of Human Papillomavirus (HPV) in first-void urine (first 20 mL of ...
How to ensure the best sequencing results from saliva and fecal samples
March 27, 2020 12:00 - 23 minutes - 31.6 MBDNA Genotek has expertise with many different non-invasive sample types including saliva for genomic and feces for microbiome analysis. With any sample type, quality is paramount to generate the best sequencing results and subsequently to produce the most accurate data. In this podcast, Mike Tayeb and Brice LeFrancois, two experts from our research and development team highlight the best practices they use in the lab with saliva and fecal samples to get optimal sequencing results.
SPARK project provides evidence for autism risk genes
February 25, 2020 13:36 - 13 minutes - 19 MBThis episode of Molecules, microbes and multiomics features an interview with Pamela Feliciano, Ph.D. who is the Scientific Director for SPARK (Simons Foundation Powering Autism Research through Knowledge) Launched in 2016, SPARK is designed to speed up research and advance our understanding of autism. SPARK, the largest study of autism ever, aims to make important progress possible. Learn about their project and why they use DNA saliva collection as their method of choice.
Industry leaders come together to support microbiome discovery
February 13, 2020 12:00 - 28 minutes - 38.8 MBAs the microbiome industry grows and evolves, so has our team of microbiome experts. In 2019, DNA Genotek’s parent company, OraSure, acquired both CoreBiome and Diversigen. Through these acquisitions, we gained Diversigen's industry recognized CLIA/CAP state-of-the-art techniques with expert consultative microbiome services, and the strength of CoreBiome's innovative scalable sequencing technology. In this podcast, Lisa Gamwell, Services Product Manager at DNA Genotek speaks with Dan Knig...
Multiomics methods investigating aging process in man's best friend
December 11, 2019 13:50 - 39 minutes - 54.4 MBDNA Genotek speaks with researchers involved in the recently launched Dog Aging Project. The goal of the Dog Aging Project is to understand how genes, lifestyle, and environment influence aging and to use that information to help pets and people increase healthspan, the period of life spent free from disease. In this podcast, we speak with Dr. Daniel Promislow from the Dog Aging Project, Dr. Elinor Karlsson from the Darwin's Ark Project and Dr. Janet Patterson-Kane from the Golden Retriever'...
The role of the microbiome in childhood determinants of cardiovascular health
November 05, 2019 14:00 - 22 minutes - 30.3 MBThe Cardiovascular Risk in Young Finns Study is a prospective longitudinal study initiated in 1980. It is one of the largest follow-up studies into cardiovascular risk from childhood to adulthood. The main aim is to determine the contribution made by childhood lifestyle, biological, and psychological measures to the risk of cardiovascular diseases in adulthood. In this podcast, Dr. Katja Pahkala and Dr. Evelina Munukka from the Univeristy of Turku, Finland apeak about this study, why they re...
PREdiCCT: the largest study on predicting IBD disease flare
September 17, 2019 16:30 - 27 minutes - 37.6 MBThis week, I interview Dr. Charlie Lees and Lee Murphy, investigators for the PREdiCCt Study (Prognostic effect of environmental factors in Crohn’s and Colitis). PREdiCCt is a major study at the University of Edinburgh that is actively recruiting now. This is the first study of its kind and it is directed towards understanding how environmental factors and the gut microorganisms influence Inflammatory Bowel Disease (IBD) flare and recovery. In this podcast, I speak with Chief Investigator Dr...
The challenges and opportunities of collecting RNA for human microbiome studies
September 09, 2019 15:01 - 16 minutes - 22.2 MBJean Macklaim is a Bioinformatician at DNA Genotek who has an extensive history with RNA research. Jean received her PhD in Biochemistry and Bachelor of Science in Human Genetics from the University of Western Ontario where she focused on sequencing technologies and bioinformatics methods to understand the structure and function of the microbiome in different disease and environmental conditions. In this podcast, Jean speaks about the challenges and potential RNA has in both the research and...
The Art of Innovation
July 16, 2019 12:30 - 7 minutes - 10.6 MBAn interview with Stephen Tang, President and CEO of OraSure Technologies and its subsidiaries DNA Genotek, CoreBiome and Novosanis. Steve spoke about how he fosters a culture of innovation across the entire organization. In the podcast, he discusses how innovation helps the organization respond to change, how developing people and creating opportunities for them makes them more innovative and how he ensures innovation is not a one time project.
Saliva as a sample type for genomic applications
June 07, 2019 14:36 - 14 minutes - 25.8 MBThis week, I interview Scott Rabuka, Director of the Genomics Program at DNA Genotek for our podcast, Molecules, Microbes and Multiomics. Scott joined DNA Genotek in 2008 as the product manager for Oragene and successfully expanded the product into a complete family of solutions for global genomic research and clinical use. He is responsible for the launch of the company's first FDA 510(k) cleared product in 2011 as well as multiple new products designed to address evolving global market opp...
Urine as a liquid biopsy for cancer detection
April 23, 2019 15:59 - 10 minutes - 9.48 MBWe recently had the opportunity to visit our new sister company, Novosanis, in Antwerp, Belgium, to talk about urine as a sample type. Novosanis is dedicated to solving urine sampling challenges through its product Colli-Pee™ - an award-winning device designed to efficiently and hygienically capture first-void urine (the first 20ml of a urine sample). I spoke with their CEO and co-founder, Vanessa Vankerckhoven about the challenges first void urine collection solves for both cancer detection...
A look ahead for the microbiome industry
March 27, 2019 12:48 - 16 minutes - 15 MBWe recently introduced listeners of Molecules, microbes and multiomics to our sister company, CoreBiome, a privately-held, Minnesota-based microbiome analysis company that accelerates discovery for customers in the pharmaceutical, agricultural, environmental and research communities. We are continuing this story via an interview with CoreBiome co-founder, Dr. Dan Knights. In this new podcast, Dr. Knights speaks to us about why the microbiome is so different from the human genome, what answ...
The microbiome challenges CoreBiome was built to solve
March 04, 2019 13:47 - 8 minutes - 7.86 MBIn the podcast, Dr. Dan Knights, co-founder and CEO of CoreBiome discusses the problems CoreBiome was built to solve and the challenges surrounding reproducibility in the microbiome field. You’ll learn why he “geeks out” about quality, efficiency, and accuracy and how his team keeps CoreBiome at the forefront of the microbiome industry. Learn more about CoreBiome and what it can do for microbiome researchers and clinicians here.