MIB Agents OsteoBites
150 episodes - English - Latest episode: 9 days ago -Each week, MIB Agents talks with the leaders and innovators in osteosarcoma surgery, research, treatment and advocacy. Questions are taken during the webinar and are included in each podcast. More information is available at www.mibagents.org
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Episodes
Out on a Limb - Travel Tips for AYA Cancer Patients
April 17, 2024 15:16 - 1 hour - 81.9 MBCamille and Mia are joined by OsteoWarriors Elise, Penelope, Sammy and Sloane to share their experiences and tips for traveling after limb salvage surgery, amputation, and/or during treatment. They discuss navigating the airport, what the deal is with wheelchairs at the aiport, getting through TSA with a prosthesis, how to find leg room in cramped airplanes and cars, managing public transportation, tips for flying, and traveling outside the US. Aside from learning some practical tips to ma...
Phase 1 Study of Cabozantinib in Combination with Topotecan-Cyclophosphamide for Patients with Relapsed or Refractory Ewing Sarcoma or Osteosarcoma
April 11, 2024 21:45 - 57 minutes - 52.5 MBKevin Campbell, MD, a pediatric oncologist at Children's Mercy Kansas City and Clinical Assistant Professor of Pediatrics, University of Missouri-Kansas City School of Medicine discusses results from the Phase 1 study assessing the safety and toxicity of cabozantinib in combination with topotecan and cyclophosphamide for relapsed osteosarcoma and Ewing sarcoma.Dr. Kevin Campbell is a pediatric oncologist at Children's Mercy Kansas City and a Clinical Assistant Professor of Pediatrics at the...
Targeting Urea Cycle Dysfunction to Prevent and Treat Osteosarcoma Metastasis
April 05, 2024 00:08 - 46 minutes - 42.5 MBRachel Offenbacher, MD, is an attending physician at Children’s Hospital at Montefiore (CHAM) and Assistant Professor, Pediatric Hematology, Oncology, Marrow and Blood Cell Transplantation at Montefiore Einstein. She joins us on OsteoBites to share her work on targeting urea cycle dysfunction to prevent and treat osteosarcoma metastasis.Since joining the Montefiore team, Dr. Offenbacher’s clinical focus has been pediatric sarcomas. As a member of a translational sarcoma research lab, Dr. Of...
osTEAo: Patient Experiences with Lung Surgery for Osteosarcoma
March 21, 2024 09:00 - 1 hour - 69.8 MBCamille and Mia are joined by OsteoWarriors Jasmine, Penelope and Walker to share their experiences with local control strategies to remove osteosarcoma lung metastasis, including surgery, radiation therapy, and cryoablation. They cover everything from their reaction to hearing they needed a lung surgery, how they prepared for surgery - both mentally and pro tips for how to make yourself comfortable in the hospital, managing their pain and nausea post surgery, recovery time for the differen...
Osteosarcoma Explorer: A Data Commons With Clinical, Genomic, Protein, and Tissue Imaging Data for Osteosarcoma Research
March 14, 2024 23:59 - 1 hour - 59.3 MBDonghan “Mo” Yang, PhD, is a researcher in the field of data science and health informatics. He joins us on OsteoBites to introduce the development of the Osteosarcoma Explorer (OSE), a data commons with clinical, genomic, protein, and tissue imaging data for osteosarcoma research. The OSE is one of the flagship projects cultivated within the CPRIT-funded Pediatric Cancer Data Core (Director: Yang Xie, PhD, Professor and Associate Dean of Data Science, UT Southwestern). The goal of the OSE...
Patient perspectives on participating in research and clinical trials
March 08, 2024 01:57 - 1 hour - 57.6 MBJennifer Mack, MD, MPH from Dana-Farber Cancer Institute/Boston Children’s and Harvard Medical School join us on OsteoBites to discuss best practices for engaging patients in research and clinical trials. Dr. Mack is also part of the PE-CGS Network (Participant Engagement and Cancer Genome Sequencing) Count Me In Research Center team and she will be discussing reasons that patients may or may not want to participate in research, ways to engage patients in designing and carrying out trials.,...
Tissue Engineering Strategies for Elucidating Osteosarcoma Biology and Drug Discovery
March 01, 2024 01:24 - 1 hour - 58.9 MBFan Yang, PhD is an Associate Professor at Stanford University with joint appointments in the Departments of Orthopaedic Surgery and Bioengineering joins OsteoBites to discuss her work on tissue engineering strategies for elucidating OS biology and drug discovery.Fan Yang, PhD is the founder and Director of Stanford Stem Cells and Biomaterials Engineering Laboratory, and also Co-director of Stanford NIH Biotechnology Training Program. Her research seeks to develop hydrogels with unique micr...
Liquid biopsy in Ewing sarcoma and osteosarcoma as a prognostic and response diagnostic: The LEOPARD Study
February 23, 2024 01:48 - 1 hour - 55.9 MBDr. David Shulman is a pediatric oncologist at Dana-Farber Cancer Institute. He studies novel therapies and biomarkers for patients with advanced sarcomas. In addition to early phase clinical trials, Dr. Shulman co-leads an effort to evaluate circulating tumor DNA, a type of "liquid biopsy," as a potential tool to improve the ways in which we treat patients with bone and soft tissue sarcomas. He joins us on OsteoBites to discuss the LEOPARD Study: Liquid Biopsy in Ewing sarcoma and Osteosar...
Managing Stress in AYA Cancer Patients
February 15, 2024 08:00 - 37 minutes - 34.6 MBA cancer diagnosis and the treatment that follows can trigger stress and anxiety. Camille is joined this week by Dr. Abby Rosenberg, an expert in helping AYA cancer patients manage stress. They chat about why being diagnosed as an adolescent/young adult has particular challenges, tools and techniques for managing stress, and how palliative care is different from hospice care (spoiler alert - it's not just for end of life care!). Listen in to learn why stress is normal, the three categories ...
Prevention of Cisplatin-induced Hearing Loss: Implications for Young People Treated for Osteosarcoma
February 09, 2024 02:55 - 1 hour - 55.4 MBDavid Freyer, DO, MS provides a review of hearing loss as a serious and permanent side effect caused by cisplatin chemotherapy, recent research regarding its prevention, and its relevance for young people treated for osteosarcoma.David R. Freyer, DO, MS is Professor of Clinical Pediatrics, Medicine, and Population and Public Health Sciences at the Keck School of Medicine, University of Southern California. He currently serves as Director of the Survivorship and Supportive Care Program in th...
TACOS: A Phase 2 Trial of Atezolizumab and Cabozantinib in OsteoSarcoma
January 26, 2024 06:25 - 59 minutes - 54.8 MBDr. Andy Livingston is a clinician and researcher in Sarcoma Medical Oncology and holds a joint appointment in Pediatric Oncology, and is Co-director of the MD Anderson Adolescent and Young Adult (AYA) oncology program. His clinical and translational research is focused on developing new treatment strategies for patients with osteosarcoma and other bone sarcomas. Dr. Livingston joins us on OsteoBites to discuss the background and scientific rationale for combining immunotherapy with cabozant...
osTEAo: Making friends after a cancer diagnosis
January 18, 2024 14:00 - 47 minutes - 43.6 MBCamille and Mia kick off Season 3 of osTEAo with a chat on friendships after a cancer diagnosis. With special guest Vicky, MIB Agents 2023 Junior Advisory Board president, Camille and Mia discuss how to rebuild a life with meaningful connections and friendships when treatment removes you from school, your sports and extracurricular activities, and seeing your friends everyday. In this frank and sometimes hilarious discussion, you'll hear about the shift from quality to quantity, the positive...
Interventions to promote physical function during and after treatment for osteosarcoma
January 11, 2024 23:55 - 1 hour - 55 MBOsteosarcoma Webinar Series: Keri Schadler, PhD and Kiri Ness, PT, PhD, FAPTA will partner to provide information about the importance of exercise for patients undergoing treatment as well as long term survivors of osteosarcoma. Together, they will provide a clinical perspective as well as an overview of the latest evidence that documents the need for and the initial success of exercise intervention during and after treatment for cancer. Dr. Schadler is an Associate Professor in the Departm...
The Cohort to Augment the Understanding of Sarcoma Survivorship Across the Lifespan (CAUSAL) study
December 15, 2023 16:36 - 36 minutes - 34 MBDebra L. Friedman, M.D., is a professor of Pediatrics in the Division of Hematology and Oncology at the Monroe Carell Jr. Children's Hospital at Vanderbilt. She is the E. Bronson Ingram Chair of Pediatric Oncology and the leader of the Cancer Control and Prevention Program and directs the Cancer Survivorship programs at the Vanderbilt-Ingram Cancer Center. Dr. Friedman's research interests lie in the long term outcomes for cancer survivors, as well as in the design of novel therapeutic proto...
Developing a Multiscale Transcriptional Atlas of Sarcoma
December 08, 2023 22:09 - 58 minutes - 54.4 MBJoshua Nash is a PhD candidate under Dr. Adam Shlien at The Hospital for Sick Children in Toronto, Canada. Joshua's research focuses on leveraging transcriptomics and machine learning to understand the overarching biology of sarcomas and mesenchymal tumours and to develop more molecularly informed and prognosticating diagnostic subtypes. -- What We Do at MIB Agents: PROGRAMS: End-of-Life MISSIONS Gamer Agents Agent Writers Prayer Agents Healing Hearts - Bereaved Parent and Sibling Support...
Immunological Mechanisms of Cancer Defense
December 01, 2023 16:26 - 59 minutes - 54.7 MBMing Li, PhD, is Member of the Immunology Program at Memorial Sloan Kettering Cancer Center and Professor at Weill Cornell Graduate School of Medical Sciences. His laboratory studies immune regulation and its relevance to diseases including cancer. Recent work has focused on the signaling, metabolic, and transcriptional mechanisms of T cell regulation as well as tumor-elicited innate and adaptive immune responses, and how this knowledge can be translated for novel cancer immunotherapy. Dr. L...
osTEAo: Long Term Osteosarcoma Survivors: Where They Were and Where They Are Now
November 16, 2023 16:00 - 1 hour - 60.9 MBIn this episode, OsteoWarriors Camille and Mia interview three long term osteosarcoma survivors. Hear from Maeve, Sloane, and Eva about their osteosarcoma stories, what the most difficult hurdles have been for them, and what advice they would give themselves if they could go back in time. While osteosarcoma is a tough journey for most patients, this episode will fill you with hope. --- What We Do at MIB Agents: PROGRAMS: End-of-Life MISSIONS Gamer Agents Agent Writers Prayer Agents Heali...
Cabozantinib as a Maintenance Therapy to Prevent Recurrence of High-Risk Pediatric Solid Tumors
October 27, 2023 17:25 - 1 hour - 58.7 MBNilay Shah, MD is a clinician-scientist and Associate Professor in the Division of Hematology/Oncology/BMT at Nationwide Children’s Hospital. His primary clinical focus is on pediatric solid tumors, including neuroblastomas, tumors of the kidneys, and rare solid tumors of childhood. His research focuses on the molecular drivers of pediatric cancers and how new treatment approaches can be taken to better target those drivers. In this role, he works to identify new uses of currently available ...
osTEAo - Coping with Cancer through Music
October 19, 2023 14:55 - 59 minutes - 55.3 MBIn this episode, OsteoWarriors Camille and Mia share songs that have resonated with them during their life with cancer. Find out why Fight Song is not their preferred anthem for AYA cancer patients and why hope can feel like a four letter word. Listen in as they break down lyrics, discuss why osteosarcoma is like a masochistic toxic ex, and examine how music can heal and help validate the feelings and emotions that AYA cancer patients deal with. You can also listen to these meaningful musica...
OsteoBites Preguntas & Respuestas con Nino Rainusso, MD
October 13, 2023 15:22 - 55 minutes - 51.5 MBOsteoBites Preguntas & Respuestas con Nino Rainusso, MD: Únase a nosotros para un episodio especial de OsteoBites en español. Nino Rainusso, MD del Texas Children's Hospital con preguntas de respuesta sobre el osteosarcoma de pacientes y cuidadores. El Dr. Nino Rainusso es miembro del equipo de tumores sólidos pediátricos y codirector del programa de cardiooncología del Texas Children's Hospital - Baylor College of Medicine. Su laboratorio se centra en comprender el papel de las células mad...
TCF-001 TRACK (Target Rare Cancer Knowledge): A Clinical Trial Studying Precision Medicine in Rare Cancers
October 06, 2023 17:26 - 59 minutes - 55.5 MBTCF-001 TRACK is a patient advocacy initiated, decentralized clinical trial enrolling patients with rare cancers and cancer of unknown primary. Patients can enroll remotely without a requirement to travel, and enrolled patients receive biomarker testing of tissue and blood at no cost, as well as treatment recommendations from a virtual molecular tumor board. This presentation will provide details on how TRACK works, and how it seeks to achieve its goals of providing patients with personalize...
Repurposing Disulfiram to Overcome Chemotherapy Resistance in Relapsed Sarcomas
September 29, 2023 16:59 - 59 minutes - 55.4 MBMatteo Trucco, MD and Kurt Weiss, MD joins us on OsteoBites to describe the collaboration that led to the current Phase 1 clinical trial repurposing the alcoholism drug disulfiram to see if it can overcome the chemotherapy resistance seen in relapsed sarcomas, including osteosarcoma. Matteo Trucco is a Pediatric Oncologist and the Clinical Director of Pediatric Hematology/Oncology at Cleveland Clinic Children’s, specializing in the care of children, teenagers and young adults battling bone ...
osTEAo Tea Spill: AYA Cancer Gab Sesh
September 20, 2023 23:16 - 58 minutes - 53.7 MBListen in this month as Mia and Sloane have a gab sesh about the daily interactions and challenges as an AYA living with cancer that get under their skin. Hear their thoughts on why there is a lot of room for improvement on Hollywood's representation of pediatric cancer patients, how cancer limits participation in a society that doesn't address the needs of people with disabilities, the difficulties around sharing their cancer story, the cliche of being brave, and why they wish there was an ...
Addressing the Unmet Scientific Challenges in Osteosarcoma Treatment through Innovative Engineering Techniques
September 15, 2023 18:44 - 58 minutes - 53.7 MBDr. Fiona Freeman is an Assistant Professor in the School of Mechanical and Materials Engineering at University College Dublin (UCD). She graduated in Biomedical Engineering in 2011 and earned her PhD from the University of Galway in 2016, focusing on developing new strategies for bone tissue regeneration. Afterward, Dr. Freeman was awarded two prestigious postdoctoral fellowships: the Government of Ireland IRC Postdoctoral Research Fellowship and the Marie Skłodowska-Curie Global Fellowship...
Implementing Multi-Targeted Tyrosine Kinase Inhibitors in Combination with Chemotherapy for Osteosarcoma
September 01, 2023 17:57 - 1 hour - 58.3 MBThis episode is sponsored is by BTG Pharmaceuticals Dr. Michael Bishop is an Assistant Member in the Solid Tumor Division of the Department of Oncology at St. Jude Children’s Hospital in Memphis, TN. His clinical practice focuses primarily on the management of children and young adults with bone and soft tissue sarcomas, and his research interests are dedicated to the development of prospective clinical trials for the treatment of osteosarcoma. Dr. Bishop graduated from the University of A...
Immune Therapies in EGFR-Expressing Cancers
August 25, 2023 15:43 - 1 hour - 57.4 MBThis presentation discusses key findings in immunotherapies from the investigator's laboratory as well as those that have shaped the landscape of both human and canine cancers. The information focuses on EGFR and HER2 based immunotherapies, including osteosarcoma, hemangiosarcoma and other cancer types in canine patients. Mechanisms of tumor growth and therapy will also be topics of discussions. --- UCLA (B.A.), Univ Notre Dame (M.S.), University of Oklahoma Health Sciences Center (Ph.D.),...
OsTEAo - An Honest Q&A with Osteosarcoma AYA Patients, Survivors, and Siblings
August 17, 2023 15:00 - 57 minutes - 53 MBOsteoWarriors Camille and Mia are joined by members of the MIB Agents Junior Advisory Board to discuss questions submitted by patients, caregivers, clinicians, and researchers. This episode was inspired by the tremendous interest and engagement in the patient panel at the MIB Agents FACTOR 2023 osteosarcoma conference. Camille, Mia, and our Junior Advisory Board discuss many topics including cancer misconceptions, the cringiest things you can say to someone with cancer, what makes them fee...
Treatment of Osteosarcoma Using Smart Targeted Drug Delivery Nanoplatforms
August 11, 2023 16:48 - 57 minutes - 53.1 MBEpisode sponsored by BTG Cancer is one of the leading causes of death worldwide. Significant efforts are still necessary to individuate new therapeutic strategies aimed to reduce cancer recurrence and to define new potential adjuvant targets for inhibiting invasion and metastasis, two significant contributors to death among patients. The increasing interest in the employment of nanostructured materials to medicine-related branches is attributable to its unique properties allowing highly ef...
MIB Agents and SARC: A Case Study in Collaboration
August 04, 2023 19:05 - 57 minutes - 53.3 MBOsteosarcoma Webinar Series: Scott Okuno, MD - SARC Medical Officer and Ann Graham, Executive Director of MIB Agents join us on OsteoBites to discuss how SARC (Sarcoma Alliance for Research through Collaboration) work together to drive collaboration in the sarcoma community and support sarcoma research. -- Dr. Scott Okuno is Professor of Oncology at Mayo Clinic in Rochester, Minnesota. He is a recognized expert in sarcoma and clinical research. Dr. Okuno has been the SARC Medical Officer s...
OSI Funded Work
July 28, 2023 15:58 - 1 hour - 56.8 MBThe Osteosarcoma Institute (OSI) is currently supporting two clinical trials and seven laboratory research projects for osteosarcoma. In this OsteoBites episode, you will meet Lee J. Helman, MD, Director of the OSI and Chand Khanna, DVM, PhD, Chair of the OSI’s Strategic Advisory Board. Dr. Helman and Dr. Khanna will provide an overview of the OSI’s osteosarcoma research portfolio and explain how the OSI identifies promising osteosarcoma research projects. Lee J. Helman, MD has been studyin...
OsTEAo - Survivor's Guilt and Grief with grief coach Lori Krause
July 20, 2023 15:00 - 57 minutes - 52.5 MBOsteoWarriors Camille and Gillian are joined by grief coach Lori Krause to discuss what survivor's grief and guilt look like and how to cope and learn to live with these feelings. --- What We Do at MIB Agents: PROGRAMS: End-of-Life MISSIONS Gamer Agents Agent Writers Prayer Agents Healing Hearts - Bereaved Parent and Sibling Support Ambassador Agents - Peer Support Warrior Mail Young Adult Survivorship Support Group EDUCATION for physicians, researchers and families: OsteoBites, weekly ...
Pretargeted Approach to Delivery of Radiopharmaceutical Therapy for Bone Cancer - a Click Chemistry Study in Canines with Osteosarcoma
July 14, 2023 15:00 - 56 minutes - 52.3 MBDr. Jeffrey Bryan earned his D.V.M. from the University of California - Davis in 1993. He worked as an Associate Veterinarian from 1993-1995 and served as Medical Director from 1995-2002 of the Irving Street Veterinary Hospital in San Francisco, CA. Bryan then completed a medical oncology residency, a Masters of Biomedical Sciences, and a PhD in Pathobiology at the University of Missouri. He received certification by the American College of Veterinary Internal Medicine in Oncology 2005. He i...
osTEAo - Coping with Humor: A Review of Cancer Memes
June 15, 2023 14:55 - 47 minutes - 43.8 MBMia and her special guest Jessie review and discuss cancer memes. Mia shares how these memes resonate with her real-life experiences, and Jessie offers perspective as a friend and partner to a cancer patient. If you are a cancer patient, you will likely laugh along and completely relate to these memes. For clinicians, friends, and family of a cancer patient, you will hear a frank (and funny!) discussion that will provide you insight into the cancer patient experience. --- What We Do at MI...
The Importance of Patient-Powered Osteosarcoma Research: Count Me In
June 09, 2023 16:28 - 1 hour - 58.2 MBDr. Katie Janeway, a pediatric hematologist-oncologist of Dana Farber/Boston's Children Hospital, and Benjamin Zola, a Project Manager at Count Me In (CMI), will be joining to share more insight into Count Me In's patient- powered Osteosarcoma research project, and the potential outcomes for discoveries that can have a direct impact on the future osteosarcoma. Count Me In (CMI) is a nonprofit research initiative on a mission to make every patient's experience count in the effort to underst...
Osteosarcoma Organoid Models: The Potential and Limitations of Personalized Avatars
June 02, 2023 19:08 - 1 hour - 56.6 MBDr. Alice Soragni, PhD, is an Assistant Professor in the David Geffen School of Medicine at UCLA, a member of the Jonsson Comprehensive Cancer Center and of the UCLA Molecular Biology Institute. She has a Master of Science cum Laude from the University of Bologna, Italy and a PhD from the ETH of Zuerich, Switzerland. Her laboratory in the Department of Orthopaedic Surgery at UCLA couples basic research into mechanisms of disease to the development of novel therapeutic strategies. The lab foc...
Reprogramming NK Cells Within the Tumor Microenvironment of Osteosarcoma Lung Metastases
May 26, 2023 17:40 - 56 minutes - 52.3 MBDr. Christian Capitini is an associate professor and the Jean R. Finley Professor of Pediatric Hematology and Oncology. He serves as co-leader of the Developmental Therapeutics Program at the University of Wisconsin Carbone Cancer Center and director of clinical innovation at the Forward BIO Institute. He has received many awards for his clinical and research contributions, including the Department of Pediatrics Gerard B. Odell Research Award, the Outstanding New Member Science Award from th...
osTEAo- Returning to Yourself: Confidence and Identity as an AYA Cancer Patient
May 18, 2023 15:27 - 47 minutes - 43.9 MBA cancer diagnosis can affect your ability to do the things you love, like sports, dance, and school, stripping your identity of your hobbies and passions. OsteoWarriors Camille and Mia chat about this loss of identity and how they cope.Listen in as they discuss what it's like dealing with a sense of loss of self and how they manage to form an identity outside of cancer. --- What We Do at MIB Agents: PROGRAMS: End-of-Life MISSIONS Gamer Agents Agent Writers Prayer Agents Healing Hearts ...
OSI Connect: Osteosarcoma Answers and Assistance
May 12, 2023 16:14 - 58 minutes - 54.1 MBOSI Connect is the Osteosarcoma Institute’s free, easy-to-use resource for patients who have been diagnosed with osteosarcoma or suffered a relapse after initial treatment. In this OsteoBites episode, you will meet Lee J. Helman, MD, Director of the OSI and Chelsey Blanks, OSI Connect Administrator. You will learn how OSI Connect works and examples of how the program has helped more than 70 patients since its launch in 2019. Lee J. Helman, MD has been studying the biology and caring for ped...
Open Clinical Trial: GD2-SADA:177Lu-DOTA Complex in Patients With Solid Tumors Known to Express GD2
May 09, 2023 19:45 - 29 minutes - 27.1 MB*Please note : The safety and efficacy of GD2-SADA:177Lu-DOTA Drug Complex have not been established and have not been approved by health authorities in the US or globally. Janet Yoon, M.D., specializes in pediatric hematology/oncology because it allows her to build long-term relationships with her young patients and their caregivers. Inspired by their resilience and strength, she stays at the leading edge of her field so that she can introduce families to the latest therapies, specifically...
SCF-Skp2 Protein Complex as a Therapy for Osteosarcoma by Blocking the Mutational Effects of Rb and p53
April 28, 2023 21:46 - 59 minutes - 54.9 MBBang H. Hoang, MD, is a board-certified orthopedic surgeon specializing in musculoskeletal tumor surgery. Dr. Hoang is an expert in benign and malignant tumors, metastatic bone disease, pathologic fractures, complex bone and joint reconstruction with large-segment prosthesis and allograft, tumors of the pelvis and sacrum, and investigational therapy for bone and soft tissue sarcoma. He is the Co-Director of the Orthopaedic Oncology Division at Montefiore and Professor of Orthopaedic Surgery ...
osTEAo - Navigating Scanxiety
April 20, 2023 15:00 - 48 minutes - 45.3 MBYou are not alone - scanxiety is real! OsteoWarriors Camille and Mia chat about scans and share their experiences with the different types of scans, from x-rays to CT scans, to MRIs and PET scans. Listen in as they discuss what it's like adapting to life that is regularly punctuated with scans and share how they cope with scanxiety. --- What We Do at MIB Agents: PROGRAMS: ✨ End-of-Life MISSIONS ✨ Gamer Agents ✨ Agent Writers ✨ Prayer Agents ✨ Healing Hearts - Bereaved Parent Support ✨ Am...
Cold Atmospheric Plasma: A New Therapeutical Option for Osteosarcoma?
April 14, 2023 17:58 - 57 minutes - 53.5 MBCristina Canal Barnils (Barcelona 1977) is Associate professor at the Department of Materials Science and Engineering, at the Technical University of Catalonia (UPC), head of the PlasmaMedLab: Plasmas for BioMedical Applications Laboratory and of the Medical Technologies: Biomaterials & Tissue Engineering research group at the IRSJD. Before joining UPC, she did different research stages at pre and postdoctoral level in different national and international research centres. She has participa...
UHRF1 Overexpression Promotes Osteosarcoma Metastasis through Altered Exosome Production and AMPK/SEMA3E Suppression
March 31, 2023 21:17 - 1 hour - 55.8 MBDr. Claudia Benavente studied Molecular Biotechnology Engineering at Universidad de Chile where her interest in pursuing cancer research first started. To further her studies, she came to the US to pursue a doctoral degree in Cancer Biology at The University of Arizona as a Fulbright scholar. She then moved on as a postdoctoral fellow to St. Jude Children’s Research Hospital in Memphis, TN where she became familiar with childhood solid tumors. Professor Benavente is currently an Associate Pr...
Stereotactic Body Radiation Therapy (SBRT) and Stereotactic Radiosurgery (SRS) for Sarcoma
March 24, 2023 16:18 - 58 minutes - 53.9 MBErin S. Murphy MD is an Associate Professor in the department of radiation oncology at the Cleveland Clinic. She completed residency at the Cleveland Clinic and a fellowship in pediatric radiation oncology at St. Jude Children’s Research Hospital. She specializes in radiotherapy and radiosurgery for brain tumors and pediatric tumors and is passionate about using aggressive local tools while maintaining quality of life for her patients. --- What We Do at MIB Agents: PROGRAMS: ✨ End-of-Life ...
osTEAo - Navigating Campus: Limb-Salvage and Amputation Patient Perspectives
March 16, 2023 15:00 - 54 minutes - 50.7 MBOsteoWarriors Camille and Mia are joined by OsteoWarriors Daniel and Kara in this episode on navigating life and campus with limb salvage surgery and amputation, which are the primary treatment options to remove an osteosarcoma tumor. Listen in as they discuss why they chose limb salvage surgery or amputation and how they manage getting around school, and share challenges and horror stories they've experienced which are sure to make you both grimace and laugh. --- Save the Date and mark yo...
Ewing Sarcoma and Osteosarcoma Have Distinct Immune Signatures and Intercellular Communication Networks
March 10, 2023 18:27 - 1 hour - 56 MBDr. Kelly M. Bailey MD, PhD, is a pediatric oncologist certified by the American Board of Pediatrics. She is assistant professor of pediatrics at the University of Pittsburgh School of Medicine. Dr. Bailey received her medical degree and PhD from West Virginia University, Morgantown, W.Va., and completed her residency in pediatrics and fellowship in pediatric hematology/oncology at the University of Michigan School of Medicine, Ann Arbor, Mich. Dr. Bailey’s clinical and research interests fo...
SarcoSIGHT- A Randomised Controlled Trial of Fluorescence Guided Sarcoma Surgery versus Standard Care
March 03, 2023 18:44 - 58 minutes - 54.5 MBSurgery along with chemotherapy is the mainstay of treatment for patients with osteosarcoma. In order to achieve a cure, during surgery healthy tissue surrounding the tumour is also removed. Whilst this reduces the chances of the cancer returning, it can also result in added pain and disability for patients, impacting their quality of life in the longer-term. Advancements in surgical technology and technique offer the hope of improved outcomes for patients. Recent developments have led to t...
Virtual Surgical Planning and 3D Printing in Pediatric Musculoskeletal Oncological Resections
February 17, 2023 17:11 - 1 hour - 61 MBJayanthi Parthasarathy BDS, MS, PhD, manages the 3D Printing Lab at Nationwide Children’s Hospital, which provides comprehensive patient-specific treatment planning and device development services from a pediatric perspective. She will discuss virtual surgical planning and 3D printing in pediatric musculoskeletal oncological resections. A trained dental surgeon with more than 3 decades of practice, Dr. Parthasarathy is a pioneer in additive manufacturing for clinical needs, specializing in ...
Two Epigenetically Distinct Cellular States in Osteo are Regulated by a State-Specific Set of Transcription Factors Driving Differential Drug Response
January 27, 2023 16:04 - 54 minutes - 50 MBEunice Lopez Fuentes is in her postdoc studies at UCSF in Sweet-Cordero Lab. She is interested in defining the mechanisms of epigenetic gene regulation in osteosarcoma. Fuentes has uncovered two epigenetic different cell states with differential drug responses. Her main goal is to gain insight into the biology of these subclasses and define how their distinct master regulators may determine new clinically relevant vulnerabilities. --- What We Do at MIB Agents: PROGRAMS: ✨ End-of-Life MISSI...
Clinical Trial: Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors
January 13, 2023 16:25 - 51 minutes - 47.8 MBMarie Nelson, M.D., is originally from Michigan, attended college at the University of Notre Dame and earned her medical degree from Loyola University Chicago Stritch School of Medicine. She finished her residency in Pediatrics at Ann & Robert H. Lurie Children’s Hospital of Chicago prior to completing a fellowship in Pediatric Hematology, Oncology, and Bone Marrow Transplantation at Children’s National Hospital in Washington, D.C. Dr. Nelson is a member of the solid tumor faculty and Assist...