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Longevity by Design

63 episodes - English - Latest episode: 7 days ago - ★★★★★ - 153 ratings

Longevity by Design is a podcast for individuals looking to experience a longer, healthier life. In each episode, Dr. Gil Blander joins a co-host and an industry expert to explore a personalized health journey. The show helps you access science-backed information, unpack complicated concepts, learn what’s on the cutting edge of longevity research and the scientists behind them. Tune into Longevity by Design and see how to add years onto your life...and life onto your years.

Nutrition Health & Fitness Science
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Episodes

The Effects of Cellular Senescence and Senolytics on Healthspan with Dr. James Kirkland

April 17, 2024 10:00 - 1 hour - 49.6 MB

Do you know what senescent (zombie) cells are and how cellular senescence and senolytics impact health? In this episode of Longevity by Design, hosts Ashley Reaver and Dr. Gil Blander are joined by Dr. James Kirkland from the Mayo Clinic, one of the world's leading figures in aging research. This episode is a deep dive into aging research, cellular senescence, and senolytics. Dr. Kirkland discusses the impact of cellular aging (senescence) on healthspan and his discovery of the first senolyt...

Aging, Mental Health, Suicide Risk & Prevention with Dr. Peter Franz

April 03, 2024 10:00 - 39 minutes - 27 MB

This episode of Longevity by Design discusses mental health and suicide risk and prevention. The following topics are discussed: depression, suicide, substance abuse, social isolation, among others also. This episode is intended to raise awareness of mental health issues and suicide risk and prevention. The topics discussed may be distressing or triggering for some individuals. Please proceed with caution if you continue to listen to this episode. Our mental health is vital for healthspan a...

XPRIZE Healthspan: Revolutionizing Human Aging & Healthspan with Dr. Jamie Justice

March 20, 2024 10:00 - 1 hour - 46.6 MB

Can we find ways to target human aging and extend healthspan? This ambitious premise is at the heart of XPRIZE Healthspan, a 7-year, $101 million global competition with an audacious challenge: to successfully develop a proactive, accessible therapeutic that restores muscle, cognitive, and immune function by a minimum of 10 years, with a goal of 20 years, in persons aged 65-80 years, in one year or less. In this episode of Longevity by Design, hosts Ashley Reaver and Dr. Gil Blander spoke w...

Longevity Genes, Blood Biomarkers of Aging, & Targeting Aging with Metformin with Dr. Nir Barzilai

March 06, 2024 11:00 - 1 hour - 54.6 MB

Aging is inevitable, but can we influence how we age? In this episode of Longevity by Design, hosts Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD,  interview Dr. Nir Barzilai—the Director of the Institute for Aging Research at the Albert Einstein College of Medicine and the Director of the Paul F. Glenn Center for the Biology of Human Aging Research and of the National Institutes of Health’s (NIH) Nathan Shock Centers of Excellence in the Basic Biology of Aging—during which he discusses gr...

The Impact of Exercise on Blood Biomarkers and InsideTracker’s New DNA Healthspan Report with Dr. Bartek Nogal

February 21, 2024 11:00 - 39 minutes - 27.4 MB

In this episode of Longevity by Design, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, sit down with Dr. Bartek Nogal from InsideTracker to explore the cutting-edge intersections of exercise, genetics, blood biomarkers, health optimization, and longevity. Dr. Bartek Nogal, with a strong background in biological engineering and genomics, dives into how personalized health data can shape our understanding of aging and wellness. He discusses InsideTracker's new innovative approach to using DN...

Ask Me Anything (AMA): Oral Health, Healthspan, and Longevity with Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD

February 07, 2024 11:00 - 55 minutes - 38.3 MB

Did you know that your oral health has a profound impact on healthspan and longevity? Do you want to learn about the connections between oral health, healthspan, and longevity and what you can do to improve your oral health to help you live longer and add more healthy years to your life? This episode of Longevity by Design is an Ask Me Anything (AMA) between Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, where they dive into the often-overlooked importance of oral health for healthspan a...

How Our Blood Impacts Brain Aging and Alzheimer’s Disease with Dr. Tony Wyss-Coray

January 24, 2024 11:00 - 1 hour - 56.2 MB

In this insightful episode of Longevity by Design, hosts Dr. Gil Blander and Ashley Reaver welcome Dr. Tony Wyss-Coray, a distinguished expert in neurology and brain aging. Dr. Wyss-Coray shares his journey from a childhood fascination with nature to becoming a leading figure in neuroscience and immunology. His initial interest in farming evolved into a passion for understanding the complexities of the human brain, particularly in the context of aging and neurodegenerative diseases. Dr. Wys...

Do NAD Analogs and Resveratrol Boost Cellular Health and Longevity With Dr. Joe Baur

January 10, 2024 11:00 - 1 hour - 49 MB

How can you increase NAD+ levels? And do higher NAD+ levels really lead to better metabolic health? What does the research say on their benefits for longevity? These topics and more are discussed in the latest episode of Longevity by Design with Dr. Joe Baur.  Dr. Baur, Professor at the Perelman School of Medicine of the University of Pennsylvania, has made key contributions to the understanding of how metabolism and dietary factors influence longevity, for example, resveratrol’s effect on ...

The Latest Updates in Longevity Research with Dr. Eric Verdin

December 13, 2023 11:00 - 1 hour - 45.7 MB

This episode of Longevity by Design features an interview with Dr. Eric Verdin—the CEO of The Buck Institute. The Buck Institute was the first center dedicated to aging research, and many discoveries within the aging field have come out of this research center.  For this episode, Dr. Verdin, Dr. Blander, and Ashely Reaver sat down in person to discuss the latest updates in longevity research. Dr. Verdin shares his opinion on questions like “is aging a disease?” and “is there a maximum lifes...

How To Be Smarter About Protein Intake With Dr. Nick Burd

November 29, 2023 11:00 - 1 hour - 44.3 MB

Dr. Nick Burd, PhD, is a skeletal muscle physiologist with an expertise in protein metabolism and exercise. In this episode, Dr. Burd discusses the importance of maintaining muscle mass as we age, expressing that “strong is the new healthy.”  While adequate protein intake is an important aspect of gaining muscle and maintaining healthspan, many people in the US actually over consume protein. In this discussion, Dr. Burd talks about how much protein we truly need, whether or not there is an ...

Tracking Your Body’s Data to Improve Health Outcomes with Dr. Sara Gottfried

November 15, 2023 13:00 - 1 hour - 57.2 MB

In this episode of Longevity By Design, Dr. Gil Blander and Ashley Reaver interview Dr. Sara Gottfried. Dr. Gottfried received her MD from Harvard Medical School and completed residency at UCSF, however she is more likely to prescribe a continuous glucose monitor and personalized nutrition plan to her patients than the latest pharmaceutical. This episode is a must listen for anyone trying to optimize their wellness plan. Dr. Gottfried discusses all the data she tracks and how that helps her...

Ask Me Anything: Lowering Cholesterol and Optimizing VO2max

October 25, 2023 12:00 - 1 hour - 58.2 MB

Did you know that blood cholesterol levels are influenced by far more than just the foods we eat? Are you eager to know how to assess healthspan using your own body's data?  This episode of Longevity by Design is an Ask Me Anything between Dr. Gil Blander and Ashley Reaver. We gathered frequently asked questions from the Longevity by Design audience and discussed topics fundamental to longevity.  Ashley Reaver begins the conversation with a deep dive into cholesterol—including the relatio...

How to Improve Your Healthspan Using DNA Insights with Dr. Bartek Nogal

October 11, 2023 12:00 - 1 hour - 49.9 MB

In this episode of Longevity By Design, Dr. Gil Blander interviews Dr. Bartek Nogal about genetic predispositions to conditions of aging. This episode goes deep into explaining how to improve your healthspan using DNA insights. Dr. Blander and Dr. Nogal talk about bone mineral density, epigenetic age acceleration, cognitive decline, risk of elevated ApoB, grip strength, and more. Knowing your genetic predispositions to certain traits can help you fine tune your wellness plan, and Dr. Nogel a...

Neurosurgery, Preventing Alzheimer’s Disease, and Optimizing VO2max with Dr. Joseph Maroon

September 27, 2023 12:00 - 1 hour - 52.8 MB

Did you know an estimated 6.7 million Americans aged 65 and older are living with Alzheimer's disease? Alzheimer’s disease is the most common form of dementia, contributing to 60–70% of dementia cases. Being that aging is the primary risk factor for developing dementia, the Longevity By Design team has been eager to discuss dementia on the show.  In this episode, Dr. Blander and Ashley Reaver, MS, RD, CSSD interview Dr. Joseph Maroon. Dr. Maroon is a professor of Neurosurgery at the Univers...

How GLP-1 Agonists Are Changing Obesity Care with Dr. Spencer Nadolsky

September 13, 2023 12:00 - 1 hour - 50.3 MB

GLP-1 agonist medications have been a popular topic of discussion recently. While this weight loss drug was designed for obesity, GLP-1 agonists like Ozempic have made their way into Hollywood. This has people questioning their safety and possible health risks, especially in the long run. Are GLP-1 agonists a quick fix for weight loss or a lifetime prescription? Who should be prescribed this medication, and what are the possible side effects?  This Longevity by Design episode features an in...

Insulin Resistance, Weight Management, and Eating Optimally with Dr. Mitch Roslin

August 23, 2023 12:00 - 55 minutes - 37.9 MB

In this episode of Longevity By Design, Dr. Blander sits down with Dr. Mitch Roslin to discuss insulin resistance. Insulin resistance has been top of mind for Dr. Blander recently, and this conversation offers new insights into how we can prevent insulin resistance through diet and lifestyle. Dr. Roslin parses out the different factors that cause insulin resistance, explaining that some are within our control (diet and lifestyle) while others are not (age and genetics). Dr. Roslin also talks...

How Hyperbaric Oxygen Therapy improves cognition with Dr. Shai Efrati

August 09, 2023 12:00 - 1 hour - 43.5 MB

Hyperbaric oxygen therapy (HBOT) is a medical treatment in which patients breathe pure oxygen at higher than normal atmospheric pressure. This increases the amount of oxygen dissolved in body tissues, enabling tissue rejuvenation and accelerated recovery. Historically, HBOT has been used for chronic wounds like diabetic foot ulcers, radiation injuries, and non-healing surgical wounds.  However, the research on HBOT is evolving and has recently suggested its use can have regenerative effects...

Using Synthetic Biology To Extend Lifespan With Dr. Nan Hao

July 26, 2023 12:00 - 1 hour - 42.2 MB

In 2023, a study was published in the journal Science sharing a breakthrough within the longevity field. This study used synthetic biology to alter the gene networks of yeast cells, and what they found was incredible. They were able to increase the lifespan of yeast cells by 82% compared to control cells. Various media outlets have covered the study with the study’s findings  sparking transformative advancements in the longevity field.   This episode is an in-depth discussion with the lead s...

How To Prevent And Reverse Insulin Resistance with Dr. Jennifer Lovejoy

July 12, 2023 12:00 - 1 hour - 55.6 MB

When you hear the word “insulin” what comes to mind first? If your first thought was diabetes, you are not alone. Insulin is most often associated with diabetes, but it plays a key role in many aspects of our health. Did you know that insulin is associated with brain health and cognition? Or that managing insulin levels can aid in weight management? In this episode, Dr. Lovejoy discusses insulin resistance, blood glucose control, and weight management. She shares several strategies to preve...

Dr. Jennifer Lovejoy—How Hormone Balance and Optimal Metabolism Promote Healthy Aging

June 21, 2023 12:00 - 1 hour - 47.1 MB

What if we told you that sugary foods aren't the only driver of insulin resistance? Many people attribute weight gain solely to a slowed metabolic rate, but the reality is that weight is influenced by dozens of other lifestyle factors.  The media often misrepresents the term ‘hormone balance,’ leaving women without adequate advice to address menopausal symptoms. In fact, certain foods can mitigate hot flashes, yet they are the same foods often torn apart by the media.  Insulin, weight mana...

Dr. John Oliffe—Overlooking Men’s Mental Health: A Threat To Longevity

June 07, 2023 12:00 - 1 hour - 43.5 MB

In this episode of Longevity By Design, Dr. Gil Blander welcomes guest Dr. John Oliffe, a renowned expert on men’s mental health. Dr. Blander and Dr. Oliffe discuss the intricacies and challenges regarding mental health faced by men in today’s world, and how when left unaddressed, can threaten men’s longevity. They delve into the complexities of modern masculinity and how traditional expectations impact men’s emotional well-being. Throughout the conversation, Dr. Oliffe shares insight into...

Dr. Emma Teeling—DNA Repair Mechanisms and Aging: Lessons From Bats

May 24, 2023 12:00 - 1 hour - 46.9 MB

In this episode of Longevity By Design, Dr. Gil Blander interviews Dr. Emma Teeling, a leading bat researcher from the University of Dublin. They delve into the extraordinary world of bats, discussing how these mammals hold the key to understanding disease resistance, immunity, and longevity. Dr. Teeling explains the unique immune system of bats and their ability to suppress inflammation—which is considered one of the primary drivers of aging. Many lessons from bats can be applied to humans,...

Dr. Renee Deehan—Why Everyone Should Care About Women’s Health

May 10, 2023 12:00 - 1 hour - 61.5 MB

In this episode of Longevity by Design, Dr. Renee Deehan discusses pertinent topics of women's health—and why women's health should matter to all. Hormone levels shift throughout a woman's lifespan, and the symptoms and risks associated with suboptimal hormone levels have an economic burden worth addressing. Tune in to learn how Dr. Deehan integrates blood biomarker testing, genomics, and fitness tracker data to steer conversations regarding health outcomes. To learn more about critical hor...

Dr. Leroy Hood + Dr. Nathan Price—How Assessing Biological Age Improves Wellness

April 26, 2023 12:00 - 1 hour - 58.1 MB

In this episode of Longevity By Design, Dr. Leroy Hood and Dr. Nathan Price discuss their approach to scientific wellness—distilling data into a simple, actionable measurement: biological age. Their goal is to leverage technology to compile data from the brain, body, gut microbiome, and more to create a model for scientific wellness. Dr. Leroy Hood and Dr. Nathan Price aim to integrate scientific wellness into the healthcare system—shifting the focus from disease-care to preventative lifesty...

Dr. Rachele Pojednic—How Exercise Improves Healthspan

April 12, 2023 12:00 - 55 minutes - 38.3 MB

In this episode of Longevity By Design, Dr. Rachele Pojednic describes the mechanism behind how exercise improves healthspan—discussing different modes of exercise and how each caters to a key health metric. Muscle integrity declines as we age, and Dr. Pojednic shares why preserving this tissue is critical for healthspan. She encourages listeners to choose the best physical activity type for themselves and quantifies how much exercise they should get per week. Finally, Dr. Pojednic discusses...

Dr. Kate Wolin—How To Use Behavioral Science To Build Healthy Habits

March 29, 2023 12:00 - 1 hour - 67.6 MB

In this episode of Longevity by Design, Dr. Kate Wolin discusses the tactics of behavior change science that can promote sustainable healthy habits. As a behavioral epidemiologist, Dr. Wolin provides actionable advice for health promotion in many contexts. She explains the science of motivation and how leveraging one’s motivation can promote behavior change. She also dives into how our environment facilitates positive or negative health behaviors and how to alter them. Tune in to hear the la...

Dr. Noah Davidsohn—Gene Therapies for Age-Related Diseases

March 15, 2023 12:00 - 40 minutes - 27.7 MB

This episode of Longevity by Design discusses groundbreaking research on the use of gene therapies to target common diseases of aging. Dr. Noah Davidsohn leverages genes associated with aging as targets for de-aging cells and reducing the burden of age-related diseases. The research appears promising—Dr. Davidsohn is confident that these findings will eventually improve human lifespan and healthspan. Tune in for conversations that dissect the latest research in the field of longevity.  For ...

Dr. Joan Mannick—mTOR's Role in Aging

February 22, 2023 13:00 - 42 minutes - 29 MB

During this episode of Longevity by Design, Dr. Joan Mannick explains how mTOR influences the aging process. She explains that this evolutionarily conserved protein is involved in several cellular functions in the body and acts on longevity-promoting pathways like autophagy. Dr. Mannick also discusses the connection between mTOR and the immune system, sharing her research on how low-dose mTOR inhibitors can upregulate antiviral immunity, creating an opportunity for more targeted vaccines for...

Dr. Andrea Maier—Mechanisms of Aging

February 08, 2023 13:00 - 51 minutes - 35.3 MB

This episode of Longevity by Design discusses topics related to longevity medicine, including mechanisms of aging, biological aging clocks, organ-specific aging, and factors that impact healthspan. With impressive clinical and research experience, Dr. Maier explains the importance of integrating longevity medicine into general practice as well as the current state of diagnostic tools within the field.  For science-backed ways to live a healthier longer life, download InsideTracker's Top 5 b...

Dr. Jennifer Garrison—Women's Health and Longevity Part 2

January 25, 2023 13:00 - 57 minutes - 39.7 MB

This episode of Longevity by Design is the second of a two-part series in which Dr. Jennifer Garrison discusses women's health and the menopausal transition. In this episode, Dr. Garrison talks about reproductive health, the hormonal fluctuations women experience during their life, and the health implications of menopause.  For science-backed ways to live a healthier longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast

Dr. Jennifer Garrison—Women's Health and Longevity Part 1

January 11, 2023 13:00 - 50 minutes - 34.5 MB

This episode of Longevity by Design discusses concepts related to women's health, including the brain-ovary connection, reproductive health, ovarian aging, and the health implications of menopause. Our guest today is Dr. Garrison, a neuroscientist, and expert in reproductive health. Dr. Garrison talks about gender inequalities in research and how her research lab aims to progress the scientific understanding of women's health and longevity.  For science-backed ways to live a healthier longe...

Dr. Marco Altini—Heart Rate Variability and the Stress Response

December 07, 2022 13:00 - 48 minutes - 33.5 MB

This episode of Longevity by Design is an in-depth discussion on heart rate variability (HRV) and the stress response. Our guest today is Dr. Altini, an HRV expert and data expert. He and Dr. Blander talk through the definition of HRV, how stress impacts the autonomic nervous system, and the many factors that influence HRV. Tune in as Dr. Altini sheds light on how to interpret and improve this highly individualized marker.  For science-backed ways to live a healthier longer life, download I...

Dr. Alex Zhavoronkov & Deepankar Nayak—Biological Aging Clocks

November 16, 2022 13:00 - 55 minutes - 38.5 MB

This episode of Longevity by Design discusses the research behind biological aging clocks, artificial intelligence, and organ-specific aging with Dr. Alex Zhavoronkov and Deepankar Nayak. In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Alex Zhavoronkov and Deepankar Nayak. Dr. Zhavoronkov and Deepankar have extensive knowledge of biological aging clocks—how they are developed, what they measure, how to interpret them, and...

Dr. Alex Zhavoronkov + Deepankar Nayak—Biological Aging Clocks

November 16, 2022 13:00 - 55 minutes - 38.5 MB

This episode of Longevity by Design discusses the research behind biological aging clocks, artificial intelligence, and organ-specific aging with Dr. Alex Zhavoronkov and Deepankar Nayak. In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Alex Zhavoronkov and Deepankar Nayak. Dr. Zhavoronkov and Deepankar have extensive knowledge of biological aging clocks—how they are developed, what they measure, how to interpret them, and...

Dr. Jennifer Elisseeff—Regenerative Medicine and Immunology

November 02, 2022 12:00 - 40 minutes - 28.1 MB

This episode of Longevity by Design discusses topics related to regenerative medicine—senescent cells, biomaterials, arthritis, immunology, and more. In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Jennifer Elisseeff. Dr. Elisseeff holds a PhD in Medical Engineering and has conducted many interesting studies relating to tissue engineering and the immune system. Tune in as Dr. Elisseeff discusses the latest science in the ...

Dr. Evelyne Bischof—Applying Longevity Medicine to Optimize Healthspan

October 19, 2022 12:00 - 46 minutes - 32 MB

This episode of Longevity by Design is all about longevity medicine, diving deep into the topic of longevity clinics, practical tools for using longevity medicine, and how this approach to healthspan differs from traditional methods of care.  In this episode of Longevity by Design, our host, Dr. Gil Blander, is joined by Dr. Evelyne Bischof, Chief Physician Associate of Internal Medicine at University Hospital Renji of Jiaotong University Shanghai and Concierge Longevity Physician for execu...

Dr. Robert Pastore—How an Early Celiac Disease Diagnosis Helps You Live a Healthier Life

October 05, 2022 12:00 - 52 minutes - 36.1 MB

In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Robert Pastore. Today’s episode is all about celiac disease—clinical manifestations, challenges in the diagnostic processes, and how this disease is especially relevant to longevity. Along with having celiac himself, Dr. Pastore holds a PhD in Biomedical Informatics and is a certified nutrition specialist—giving him a personal and unique perspective on this condition. Tune in...

Dr. Filipe Gomes Cabreiro—How The Gut Microbiome Impacts Longevity

September 21, 2022 12:00 - 45 minutes - 31.5 MB

In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Filipe Cabreiro. An expert in the gut microbiome and principal investigator at The Cabreiro Lab, Dr. Cabreiro discusses the latest science on the connection between gut microbial and healthy aging. Join us to learn how to improve microbial diversity and assess gaps in the knowledge that are currently under investigation. For science-backed ways to live a healthier, longer li...

Dr. Matt Johnson—Continuous Glucose Monitoring in Healthy People

September 07, 2022 12:00 - 48 minutes - 33.4 MB

In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Matt Johnson. Dr. Johnson is the Director of Clinical Research at Dexcom—a leading company in diabetes care through the use of continuous glucose monitoring. With extensive knowledge in diabetes, metabolic health, and exercise physiology, Dr. Johnson talks through his research and gives insight into the latest science in the field of longevity.  For science-backed ways to li...

Dr. Dudley Lamming—Surprising Findings From Protein-Restriction Studies

August 24, 2022 12:00 - 45 minutes - 31.6 MB

In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Dudley Lamming, an Associate Professor at the University of Wisconsin-Madison School of Medicine in the Division of Endocrinology, Diabetes, and Metabolism. Tune in as Dr. Lamming discusses his research on protein restriction and fasting. As the principal investigator of his lab, Dr. Lamming has extensive knowledge of nutrient signaling pathways and how dietary patterns promo...

Dr. Mitch Roslin—Preventative vs Reactive Scientific Approach to Weight Management

August 10, 2022 11:00 - 1 hour - 42.9 MB

In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Mitch Roslin, Chief of Bariatric Surgery at Lenox Hill Hospital in New York City. During this conversation with Dr. Mitch Roslin, he talks in detail about the obesity epidemic—he touches on taking a preventative, upstream approach, causes, consequences, and everything in between. Dr. Roslin shares his experience as a bariatric surgeon, and the important role this surgery has ...

Dr. Krista Varady—Does Human Research on Intermittent Fasting Support Longevity?

July 27, 2022 12:00 - 43 minutes - 30.2 MB

In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Krista Varady, Professor of Nutrition at the University of Illinois, Chicago. Research on intermittent fasting is largely conducted in cellular and animal models. Dr. Krista Varady is one of few scientists to conduct intermittent fasting clinical trials in humans. Tune in as Dr. Krista Varady discusses the latest science in the field.  For science-backed ways to live a healt...

Dr. Ronald Krauss—A Proactive Approach to Heart Health

July 06, 2022 12:00 - 53 minutes - 37 MB

In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Ronald Krauss, Professor of Medicine at UCSF, and Adjunct Professor of Nutritional Sciences at UC Berkeley. Tune in as Dr. Ronald Krauss discusses the contributing factors to atherosclerosis, the biomarkers most associated with heart disease, and components of a heart-healthy diet. For science-backed ways to live a healthier, longer life, download InsideTracker's Top 5 biom...

Dr. Roger Fielding—The Prevention of Age-Related Muscle Loss

June 22, 2022 12:00 - 42 minutes - 29.2 MB

In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Roger Fielding, Associate Director of the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University. Tune in as Dr. Roger Fielding describes how proper nutrition and being physically active build muscle and prevent age-related muscle loss.  For science-backed ways to live a healthier, longer life, download InsideTracker's Top 5 biomarkers for longevity eBo...

Dr. Mariette Abrahams—Personalized Nutrition for Sustainable Change

June 08, 2022 12:00 - 1 hour - 42.5 MB

In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Mariette Abrahams, CEO, and Founder of Qina, the first hub for data insights on Personalized Nutrition. Tune in as Mariette Abrahams discusses personalized nutrition and how to turn simple actions into sustainable health changes.  For science-backed ways to live a healthier, longer life, download InsideTracker's Top 5 biomarkers for longevity eBook at insidetracker.com/podcast

Dr. George Church—Gene Therapy and Aging

May 18, 2022 11:00 - 29 minutes - 20 MB

In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. George Church, Professor of Genetics at Harvard Medical School. Tune in as Dr. George Church discusses the many roles of gene therapy, including its ability to reverse age-related diseases. For science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast

Dr. Eric Verdin—The Effect of Food on Longevity

May 06, 2022 12:00 - 1 hour - 41.5 MB

In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Eric Verdin, the President and Chief Executive Officer of the Buck Institute for Research on Aging. Tune in as Dr. Eric Verdin discusses nutrient sensing, epigenetic regulation, and recent research on the impact of foods on longevity. To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eBook at insidetracker.com/podcast

Dr. Ali Torkamani—Genomics and Aging

April 20, 2022 12:00 - 38 minutes - 26.6 MB

Your genetics can uncover many things about you. They can influence how you look and behave, to name a few. But your genes are not deterministic; they don't tell your entire story. In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Ali Torkamani, Director of Genome Informatics at the Scripps Research Translational Institute. Tune in as Dr. Ali Torkamani discusses how genetics impact lifespan and healthspan, why genetics aren...

Dr. Eran Segal—The Value of Personalized Nutrition

April 06, 2022 12:00 - 40 minutes - 28 MB

In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Eran Segal, Faculty Member at The Weizmann Institute of Science in Israel. Tune in as Dr. Eran Segal discusses the value of personalized nutrition, how data contributes to our knowledge of personalized food responses, and the relationship between food and longevity. To learn more about science-backed ways to live a healthier, longer life, download InsideTracker's InnerAge eB...

Dr. Raul Mostoslavsky—SIRT 6 and the Hallmarks of Aging

March 25, 2022 12:00 - 1 hour - 42 MB

In this episode of Longevity by Design, our hosts, Dr. Gil Blander and Ashley Reaver, MS, RD, CSSD, are joined by Dr. Raul Mostoslavsky, the Laurel Schwartz Professor of Oncology at Harvard Medical School.  Dr. Raul Mostoslavsky has studied sirtuin functions in cancer for many years and has identified a pathway responsible for tumor growth in 30% to 40% of pancreatic cancer patients and more recently identified metabolism as a heterogeneous feature of cancer. Dr. Raul Mostoslavsky discusses...