This week on *The Heart of Innovation* Hosted by Interventional Cardiologist Dr. John Philips and Emmy Award Winning Journalist Kym McNicholas, The focus is on groundbreaking treatment for hard-to-treat blood pressure. The featured guest is Interventional Cardiologist Dr Eric Secemsky, Director of Vascular Intervention at BIDMC and Section head of Intervetional Cardiology and Vascular research at the Richard. A. and Susan F. Smith Center for Outcomes Research in Cardiology at BIDMC. Dr. Secemsky delves into the prevalence of high blood pressure, affecting nearly half of American adults, with many being unaware of their condition or facing challenges in consistently accessing or adhering to medications. Shockingly only one in four individuals with high blood pressure have it under control, underscoring the urgency of addressing this public health concern. The discussion highlights the subset of patients facing treatment resistant hypertension, where standard medication prove ineffective or intolerable, posing increased risks of heart of disease, stroke, and cardiovascular complications. Dr. Secemsky introduces the pioneering procedure of renal denervation (RDN), which involves permanently disrupting the nerves, controlling the kidneys' arteries. This innovative approach, developed, offers a potential solution for bringing treatment resistant hypertension back under control, offering hope for patients facing persistent challenges in managing their condition. The episode provides a comprehensive exploration of the groundbreaking RDN procedure, offering valuable insights into a first-of-its kind treatment for high blood pressure. Dr. Secemsky's expertise and the innovative advancements in cardiovascular care showcased in this episode underscore the ongoing pursuit of transformative solutions in the field of interventional cardiology. Tune into * The Heart Of Innovation* for an in-depth discussions on this breakthrough treatment for hypertension and its potential impact on reshaping the landscape of vascular care.