Ep. 156: dooming ourselves with medicine

Our favorite boffin, Eileen Marks-Nelson, is here to chat with us about a listener science concern that turned out to be WAY more troubling than we even anticipated: Antimicrobial resistance. Medicine has extended our lives, but has our use of it shortened them?

Highlights:

[0:00] Marko tells CoRri and Eileen about Miriam Rodriguez, the middle aged Mexican woman who took on the cartels solo to get justice for her daughter
[15:09] Mark’s American child accent leads us to a brief discussion of Sylvester Stallone and the Rocky films, and then. we remember to introduce our pal Eileen Marks-Nelson
[22:04] What we watched! (Fall of the House of Usher, The Reckoning, , Friday the 13th: A New Beginning, Totally Killer, Vampire in Brooklyn, 10 Cloverfield Lane, Ernest Scared Stupid, Deadstream, Train To Busan, Dead Alive, The Host, Carrie, A Girl Walks Home Alone At Night, Insidious, VHS85, The Creator)
[69:10] Eileen tells us about antimicrobial resistance, and why we’re sleeping on one of the biggest threats to human existence

Stuff we referenced:

History of medicine – 20th Century, Advancements, Innovations | Britannica
Bacteria | Basic Biology
Ancient brew masters tapped antibiotic secrets | ScienceDaily
Tetracycline-Labeled Human Bone from Ancient Sudanese Nubia (A.D. 350) | Science
Moulds in Ancient and more recent medicine 
Antiviral Resistance: Antivirals, Antimicrobial Resistance, HIV (clevelandclinic.org)
The Challenge of Antibiotic-Resistant Staphylococcus: Lessons from Hospital Nurseries in the mid-20th Century
ALEXANDER FLEMING Penicillin Nobel Lecture, December 11, 1945
Antibiotics: Conventional Therapy and Natural Compounds with Antibacterial Activity—A Pharmaco-Toxicological Screening
Unearthing the story of the first antifungal drugs
Penicillin | Discovery, History, Uses, Types, Side Effects, & Facts | Britannica
Methicillin-resistant Staphylococcus aureus emerged long before the introduction of methicillin into clinical practice
Changes in Intestinal Flora of Farm Personnel after Introduction of a Tetracycline-Supplemented Feed on a Farm | NEJM

Our favorite boffin, Eileen Marks-Nelson, is here to chat with us about a listener science concern that turned out to be WAY more troubling than we even anticipated: Antimicrobial resistance. Medicine has extended our lives, but has our use of it shortened them?

Highlights:

[0:00] Marko tells CoRri and Eileen about Miriam Rodriguez, the middle aged Mexican woman who took on the cartels solo to get justice for her daughter
[15:09] Mark’s American child accent leads us to a brief discussion of Sylvester Stallone and the Rocky films, and then. we remember to introduce our pal Eileen Marks-Nelson
[22:04] What we watched! (Fall of the House of Usher, The Reckoning, , Friday the 13th: A New Beginning, Totally Killer, Vampire in Brooklyn, 10 Cloverfield Lane, Ernest Scared Stupid, Deadstream, Train To Busan, Dead Alive, The Host, Carrie, A Girl Walks Home Alone At Night, Insidious, VHS85, The Creator)
[69:10] Eileen tells us about antimicrobial resistance, and why we’re sleeping on one of the biggest threats to human existence

Stuff we referenced:

History of medicine – 20th Century, Advancements, Innovations | Britannica
Bacteria | Basic Biology
Ancient brew masters tapped antibiotic secrets | ScienceDaily
Tetracycline-Labeled Human Bone from Ancient Sudanese Nubia (A.D. 350) | Science
Moulds in Ancient and more recent medicine 
Antiviral Resistance: Antivirals, Antimicrobial Resistance, HIV (clevelandclinic.org)
The Challenge of Antibiotic-Resistant Staphylococcus: Lessons from Hospital Nurseries in the mid-20th Century
ALEXANDER FLEMING Penicillin Nobel Lecture, December 11, 1945
Antibiotics: Conventional Therapy and Natural Compounds with Antibacterial Activity—A Pharmaco-Toxicological Screening
Unearthing the story of the first antifungal drugs
Penicillin | Discovery, History, Uses, Types, Side Effects, & Facts | Britannica
Methicillin-resistant Staphylococcus aureus emerged long before the introduction of methicillin into clinical practice
Changes in Intestinal Flora of Farm Personnel after Introduction of a Tetracycline-Supplemented Feed on a Farm | NEJM
Drug Companies Accept FDA Plan To Phase Out Some Animal Antibiotic Uses : The Salt : NPR
E-I-E-I-Oh no: Decades of antibiotics in farm animals lead to deadly superbugs | Grist
Study: Farmed Fish Could Be Another Source of Antibiotic Resistance | Food Safety News
Recent Advances in the Discovery of Novel Antiprotozoal Agents
Drug Development to Protozoan Diseases
WHO’s first global report on antibiotic resistance reveals serious, worldwide threat to public health
Humans Can No Longer Ignore the Threat of Fungi
Antimicrobial resistance: a global threat | UNEP – UN Environment Programme
AMR2023_summary_EN.pdf (unep.org)
When the drugs don’t work: can we do anything about antimicrobial resistance? | Global development | The Guardian
Malaria-causing parasites resistant to both treatment and detection have emerged in Ethiopia
Antibiotics: Combatting Tolerance To Stop Resistance
COVID-19 Reverses Progress in Fight Against Antimicrobial Resistance in U.S.
Paxlovid-Resistant Covid ‘Discovered’ Should We Worry?
Paxlovid Resistance: Is It Just a Matter of Time Now?
Disinfectant resistance in bacteria: Mechanisms, spread, and resolution strategies – ScienceDirect
Resisting disinfectants | Communications Medicine (nature.com)
U.S. Antibiotic Awareness Week Toolkit 2022 (cdc.gov)
A Superbug Stalked My Daughter and Stole Her Life. Phage Therapy Could Have Saved Her | Blogs | CDC
An insight into the antifungal pipeline: selected new molecules and beyond
Using viruses to treat antibiotic-resistant bacterial infections
Nanoantibiotics: Functions and Properties at the Nanoscale to Combat Antibiotic ResistanceMicrobes that cause cavities can form superorganisms able to ‘crawl’ and spread on teeth