Invisible Forces artwork

Invisible Forces

21 episodes - English - Latest episode: about 2 years ago - ★★★★★ - 115 ratings

Invisible Forces is a podcast that investigates the unseen influences that drive our spending, our saving and our global economy.

Hosted by Jefferies' insider Shannon Murphy, season three is all about one invisible force – the alchemy that can turn a series of unlikely events, surprises and setbacks into medicine’s biggest successes.

We’ll hear from biotech industry leaders and our own Jefferies experts about some of the biggest breakthroughs in medical history – and the investments that brought them into reality.

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Episodes

It's Not Where, it's What: Targeted Oncology and the Keys to Solving Cancer

March 28, 2022 04:05 - 20 minutes - 9.91 MB

If you had lung cancer, you’d take one kind of drug. If you had liver cancer, you’d take another drug. Makes sense, right? But scientists have found another, more effective, more targeted way to treat cancer — one that you need a code to unlock. In this episode we look at the surprising history and the hopeful future of immunotherapy, and how the genetic code of cancer itself has been used to find a way to treat the disease. Featuring: Neeha Zaidi is a medical oncologist at Johns Hopkins S...

When Your Home is the Hospital: Tech-Enabled Healing

March 14, 2022 04:05 - 19 minutes - 9.5 MB

Healthcare innovations aren’t just about drugs, but how care is delivered. But one of the fastest-growing areas of health care is focusing less on WHAT’s wrong with you, but WHERE the healing actually happens, and HOW doctors can deliver that care right to your home. In this episode we learn how a fitness craze from the 80’s is helping provide medical care right to a patient’s front door. Featuring: Raphael Rakowski is the founder of Medically Home Elizabeth Krupinski is a professor at Em...

Cracking the Code that Runs Us: The Future of Gene Therapy

February 28, 2022 05:05 - 19 minutes - 9.46 MB

The discovery of DNA in the 1850s allowed us to see into the genetic code of individual humans. Now gene editing, a technique by which the gene or genes that make us susceptible to some diseases, allows that code to be rewritten. In this episode we look at the ways in which gene editing is being used to turn that century-old breakthrough into the future of medicine. Featuring: Pino Ciaramella is the chief scientific officer and president of Beam Therapeutics  Paul Offit is the director of...

Breaking the Blood Brain Barrier: The Quest to Cure Neurodegeneration

February 14, 2022 05:05 - 18 minutes - 8.89 MB

Thanks to modern medicine, we are living longer lives than ever before. But our longer lives have led to an increase in age-related degenerative illnesses like Alzheimer’s disease, Parkinson’s and ALS – neurological degenerative disorders that have proven very difficult to treat because of one of the strongest security systems in the human body: The Blood Brain Barrier. This episode looks at how an idea as old as the Trojan Horse could be used to finally break down that barrier for good. Fe...

From Zero to Hero: The Story Behind the mRNA Vaccine

January 31, 2022 05:10 - 18 minutes - 17.5 MB

We kick off this new season with a medical breakthrough story you might THINK you know, but isn't that straightforward. We dive into how the "speedy" development of mRNA vaccines is actually a story with decades of twists and turns. In this episode we look at the mRNA technology that is behind many COVID-19 vaccines, and how an idea that once looked like it was destined to fail got a new life just in time to save so many of ours. Featuring: Dr. Thomas Madden is a biochemist and founder and...

Hopeless Optimism

January 31, 2022 05:05 - 19 minutes - 20.5 MB

Throughout this season, we are exploring some of the amazing medical breakthroughs that have changed lives – and continue to change what’s possible in the world of medicine. And all of this progress stems from investment: of time, of money, of research and ingenuity. In this episode, we’re looking at the common thread that links all the incredible stories we’ll be hearing over the coming season: that alchemy that brings about these life-saving innovations in healthcare. Featuring: Rachita ...

Introducing Invisible Forces Season Three

January 03, 2022 08:05 - 1 minute - 1.51 MB

Invisible Forces is a podcast that investigates the unseen influences that drive our spending, our saving and our global economy.  Hosted by Jefferies' insider Shannon Murphy, season three is all about one invisible force – the alchemy that can turn a series of unlikely events, surprises and setbacks into medicine’s biggest successes. We’ll hear from biotech industry leaders and our own Jefferies experts about some of the biggest breakthroughs in medical history – and the investments that ...

An All-Encompassing Economy

October 06, 2020 04:05 - 25 minutes - 23.8 MB

Culturally in 2020, the conversation around racial injustice has hit a breaking point. COVID-19 exacerbated inequities in health outcomes for Black and Latino Americans, and in the wake of George Floyd’s death, we’ve seen a massive movement for enduring change. The people have spoken. But how will businesses, markets and economies respond? Today, consumers are seeking ways to support the Black-owned businesses with their dollars, and companies are looking to hire more equitably and inclusiv...

A New Peace of Mind

September 22, 2020 04:05 - 24 minutes - 22.5 MB

2020 has been a year of instability and upheaval, so it’s no surprise many of us have been especially focused on our security. And that comes in many forms – securing our health, our homes, our finances, and even our digital lives. We used to talk about ‘safety in numbers’ – but during the pandemic as we’ve been in quarantine and isolation, we’ve had to rethink what security looks and feels like today. In this episode, hosts Shannon Murphy and Erin Shea explore how this need for fortificati...

Lean, Mean and Green: the Future of Sustainable Businesses

September 08, 2020 04:05 - 22 minutes - 21.5 MB

Consumers today, especially younger buyers, are in the market for more environmentally friendly products - and the good news is, their options are only growing. Hosts Shannon Murphy and Erin Shea look at how the trend towards conscious consumption is driving change in just about every industry, from fashion to food to home decor.  In this episode we dig into how tech is powering green innovations in a wide range of industries. We hear from business leaders about how this force is not only g...

The Changing Face of Urban Space

August 25, 2020 04:05 - 24 minutes - 22.5 MB

The global pandemic has made many of us think differently about the cities we live in. While lockdowns closed many of the amenities that make cities desirable, work-from-home orders showed us we can really work from anywhere. Hosts Shannon Murphy and Erin Shea are joined by equity researcher Jon Matuszewski, whose research shows that many city-dwellers are considering leaving for the suburbs – but will they really move? In this episode, we explore the future of our cities, and how the push-...

When Tech is Your Tailor

August 11, 2020 04:05 - 26 minutes - 24.8 MB

From the ads we see, to what we buy, and even how we're treated when we get sick, the world is getting more bespoke and personalized every day. For consumers, personalization offers the promise of a better, more intimate shopping experience and of products that are more finely tuned to their exact needs and interests. For businesses, personalization can be an effective way to boost sales, customer satisfaction and brand loyalty, all while minimizing costs and overhead. In this episode, hosts...

Crying Over Spilled Milk: The Disruption Solution

July 28, 2020 04:05 - 28 minutes - 26.9 MB

The outbreak of COVID-19 has exposed major weaknesses in our global supply chain. Governments, manufacturers, retailers, small businesses, individual consumers — all have been hit hard by the shutting down of international borders and travel stoppage. For some, supply has been the problem — how do you secure access to the products you need when shipping routes are closed and much of the world is on lockdown? For others, it’s been the opposite problem — how do you offload stockpiles of invent...

Coming Soon: Season Two

July 14, 2020 04:05 - 55 seconds - 1.3 MB

The world is changing at a rapid pace. And many of the forces driving these changes can’t be seen at all. Hosted by Jefferies insiders Shannon Murphy and Erin Shea, Invisible Forces is a show about the unseen influences that are rapidly transforming our way of life and global economy. With surprising stories and expert interviews, we’re looking into the future at where we'll be living, how we'll be working, what we'll be buying ... and why. Season Two premieres July 28.

What Makes Makers Tick?

October 15, 2019 10:00 - 23 minutes - 21.5 MB

In our season finale, we take a step back and explore one invisible force that has underpinned every episode in the season so far: the brilliant entrepreneurs, thinkers, and founders behind groundbreaking and culture-shifting companies. We talk to three successful founders about the entrepreneurial spirit that drives their work: Aaron Rasmussen, who just launched Outlier.org and co-founded MasterClass, Angela Lee of 37 Angels, and Transfix CEO Drew McElroy. They share candid insights about w...

Building a Boom: Brand Lessons for Creating Explosive Value

October 08, 2019 12:19 - 19 minutes - 18.4 MB

In this episode, we’re going inside an industry boom to understand what leads to value creation and sustained growth in today’s world — which is shaped increasingly by social media influence, e-commerce, and digitally native companies. We’re talking about the beauty industry. Jefferies analyst Steph Wissink will walk us through what’s been happening in this sector over the past decade. It’s an industry that just underwent a long boom period. But as Steph explains, the lifecycle of booms in t...

A Tech Revolution for Financial Services

October 01, 2019 10:00 - 28 minutes - 26.4 MB

Artificial intelligence is helping move the financial services sector into a new era of operation. We’ll learn about the invisible forces shaping how AI and other technologies could reinvent the industry in the coming years. Our hosts are joined by Jefferies Managing Director and technology lead Vaughn Harvey and Jesse McWaters, financial innovation lead for the World Economic Forum. We’ll also hear from Betterment CEO Jon Stein and IEX CEO Brad Katsuyama, two entrepreneurs already relying o...

You Are What You Buy

September 24, 2019 10:00 - 22 minutes - 20.4 MB

Consumers today have a very different relationship with the products they buy. Jefferies analyst Randy Konik explains that there are forces propelling consumer value beyond price points. More than ever, individuals’ core beliefs are coming into play when making purchasing decisions. And in response, brands are adjusting their products and their messages. We’ll get a look at how these shifts are playing out, from the diamond industry to sporting goods.

From Bench to Bedside: Speeding Up a New Era of Biotech Innovation

September 17, 2019 10:00 - 25 minutes - 23.4 MB

Our hosts sit down with Jefferies analyst Mike Yee and strategist Jared Holz to uncover the invisible forces driving change in a sector that affects us all: healthcare. We’ll learn about why biotech is on the precipice of an explosion of new drugs and treatments. We’ll meet a family whose life has already changed thanks to one of these advancements, and also hear from one of the doctors behind it.

Mobility: The Ten Trillion Dollar Question

September 10, 2019 10:00 - 20 minutes - 18.9 MB

The mobility sector makes up one of the world’s largest economies and the forces driving changes within it could result in trillions of dollars of value creation — or loss — in the future. Storm Duncan, Jefferies’ Global Head of Tech-Enabled Mobility, joins our hosts to explain the factors at work. We’ll also hear from two entrepreneurs disrupting different areas of mobility: Lime CEO Brad Bao and Drew McElroy, the CEO of Transfix. They weigh in with their personal experiences of how technol...

Coming Soon: Invisible Forces

August 27, 2019 18:52 - 1 minute - 1.6 MB

There are hidden currents — forces that we can’t see — driving change in the world and shaping the global economy. They’re affecting everything from how we get around, to what we buy, to how diseases are treated. And if you want to stay ahead, it’s crucial to understand them.