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IMPACT Medicom

67 episodes - English - Latest episode: 9 days ago -

We are a medical communications company with a passion for developing high-quality content. We write & design content for healthcare professionals and patients in a variety of therapeutic areas. If you like our podcast, please take the time to rate it and subscribe. See our website for more information, video capsules, and podcasts at: https://www.impactmedicom.com. 

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Episodes

Cutting Edge Advances in the Treatment of Lung Cancer

April 19, 2024 16:00 - 15 minutes - 10.5 MB

In this episode, Dr. Barbara Melosky discusses cutting edge approaches to the treatment of Lung Cancer, including the use of artificial intelligence and novel therapeutic approaches such as cancer vaccines and new targeted therapies. Our Guest: Dr. Barbara Melosky Dr Melosky is a Professor of Medicine at the University of British Columbia and a Medical Oncologist in Vancouver at BC Cancer. Dr. Melosky specializes in the field of thoracic malignancy. She sits on the Executive Lung Site Commi...

Precision Medicine Series: Ep15: Biomarkers in Upper GI Cancers

April 18, 2024 13:00 - 41 minutes - 28.5 MB

Welcome to our podcast episode on diagnostic, prognostic and predictive biomarkers for the treatment of upper GI cancers. In this episode, Dr Brezden-Masley (medical oncologist) and Dr Streutker (pathologist) discuss the latest biomarkers that may inform treatment of upper GI cancer.  Our Guests: Dr. Christine Brezden-Masley Dr.  Brezden-Masley is a Medical Oncologist and the Director of the Marvelle Koffler Breast Centre at Mount Sinai Hospital as well as the Medical Director of Cancer Pr...

Immunotherapy for Kidney Transplant Patients with Skin Cancer

March 25, 2024 16:00 - 21 minutes - 14.8 MB

In this podcast episode, Dr. Evan Lipson discusses the use of immunotherapy for patients with skin cancer who have had a kidney transplant. Our guest: Dr. Lipson is an internationally-recognized skin cancer and immunotherapy specialist at Johns Hopkins. Dr. Lipson leads cutting edge clinical trials for patients with melanoma and other skin cancers. As a member of the Johns Hopkins Melanoma and Cancer Immunology Programs, he focuses on evaluating novel therapies for patients with high-risk ...

Management of Cutaneous Squamous Cell Carcinoma (cSCC): A Surgeon’s Perspective

March 25, 2024 16:00 - 24 minutes - 16.6 MB

In this video capsule, Dr. Mark Taylor discusses the surgical implications for the treatment of cSCC. This podcast episode is best viewed alongside the slides, which can be found in the video capsule version: https://www.youtube.com/watch?v=uk5JEUjbkDE&t=127s.  Our Guest: Dr. S. Mark Taylor is a Facial Plastic and Reconstructive surgeon in Halifax, Nova Scotia. He is currently a Professor of Surgery at Dalhousie University. His expertise and clinical interest includes rhinoplasty/nasal sur...

LIVE FROM ASH 2023: Isa-CYBORD induction chemotherapy in newly diagnosed, transplant eligible MM

December 18, 2023 14:00 - 16 minutes - 11.7 MB

In this podcast episode, Dr. Rami Kotb and Dr. Donna Reece discuss results of the CMRG Isa-CYBORD trial presented at the ASH 2023 meeting, and the implications of the results for Canadian clinical practice. Our Guests: Dr. Rami Kotb is a physician in the Division of Hematology, Department of Medical Oncology & Hematology at CancerCare Manitoba, Winnipeg, MB, Canada Dr Donna Reece is the Director and a Professor of Medicine in the Program for Multiple Myeloma and Related Diseases at the Uni...

Live from ASH 2023: Dr Brown Discusses Updated Results of the ALPINE Trial in CLL

December 07, 2023 00:00 - 13 minutes - 9.52 MB

In this episode of our podcast, recorded at the American Society of Hematology (ASH) in San Diego, California, we discuss  updated results of the ALPINE trial with Dr. Jennifer Brown. The ALPINE trial examined the efficacy and safety of zanubrutinib versus ibrutinib for the treatment of CLL.  Our Guest: Dr. Jennifer Brown is the Director of the CLL Center of the Division of Hematologic Malignancies at Dana-Farber Cancer Institute and Professor of Medicine in the Field of Hematologic Oncolog...

First-line treatment strategies for the management of la/mUC: S2 Ep 5 - ESMO 2023: Discussion on 1L LA/mUC

October 26, 2023 19:00 - 32 minutes - 22.3 MB

In this video capsule series, we discuss the first-line treatment strategies for the management of locally advanced metastatic urothelial carcinoma in Canada. This fifth episode of the series was recorded live from ESMO 2023 with Dr. Thomas Powles, who presented results of the EV-302 trial, and Dr. Normand Blais, Dr. Srikala Sridhar, and Dr. Bernie Eigl, who discussed the impact of new data from trials on 1L LA/mUC . Our Guests: Dr. Thomas Powles: Dr Thomas Powles is a Professor of Genito...

First Line la/mUC Evolving Treatment Strategies: S2 Ep 3 - Case Discussion

September 18, 2023 13:00 - 8 minutes - 5.61 MB

In this podcast series, we discuss the first-line treatment strategies for the management of locally advanced metastatic urothelial carcinoma in Canada.  This second part of the series is based on a live webinar presented on September 12th, 2023 by Dr. Normand Blais from the CHUM Cancer center in Montreal, Dr. Terence Friedlander from the Zuckerberg San Francisco General Hospital, and Dr. Srikala Sridhar from the Princess Margaret Cancer Center in Toronto. In this third episode taken from ...

First Line la/mUC Evolving Treatment Strategies: S2 Ep 1 - Unmet Needs

September 18, 2023 13:00 - 10 minutes - 7.34 MB

In this podcast series, we discuss the first-line treatment strategies for the management of locally advanced metastatic urothelial carcinoma in Canada.  This second part of the series is based on a live webinar presented on September 12th, 2023 by Dr. Normand Blais from the CHUM Cancer center in Montreal, Dr. Terence Friedlander from the Zuckerberg San Francisco General Hospital, and Dr. Srikala Sridhar from the Princess Margaret Cancer Center in Toronto. In this first episode taken from...

First Line la/mUC Evolving Treatment Strategies: S2 Ep 2 - First-Line Treatment

September 18, 2023 13:00 - 14 minutes - 10.2 MB

In this podcast series, we discuss the first-line treatment strategies for the management of locally advanced metastatic urothelial carcinoma in Canada.  This second part of the series is based on a live webinar presented on September 12th, 2023 by Dr. Normand Blais from the CHUM Cancer center in Montreal, Dr. Terence Friedlander from the Zuckerberg San Francisco General Hospital, and Dr. Srikala Sridhar from the Princess Margaret Cancer Center in Toronto. In this second episode taken from...

First Line la/mUC Evolving Treatment Strategies: S2 Ep 4 - Round Table Discussion

September 18, 2023 13:00 - 26 minutes - 18.4 MB

In this podcast series, we discuss the first-line treatment strategies for the management of locally advanced metastatic urothelial carcinoma in Canada.  This second part of the series is based on a live webinar presented on September 12th, 2023 by Dr. Normand Blais from the CHUM Cancer center in Montreal, Dr. Terence Friedlander from the Zuckerberg San Francisco General Hospital, and Dr. Srikala Sridhar from the Princess Margaret Cancer Center in Toronto. In this fourth and final episode ...

Precision Medicine Series: Ep14: External Quality Assurance in Biomarker Testing

June 19, 2023 13:00 - 39 minutes - 26.9 MB

Welcome to our podcast episode on external quality assurance (or eQA) for testing biomarkers in oncology, hosted by Anna Christofides. In this episode,  we discuss with Dr. Emina Torlakovic, the use of eQA to aid in the improvement of biomarker testing in Canada . Our Guest: Dr. Emina Torlakovic is a Professor in Department of Laboratory Medicine and Pathobiology at the University of Toronto. She is also a Staff Hematopathologist and Director of Biomarker Development and Quality Assurance...

Podcast Series - Urothelial Carcinoma: Management of Enfortumab Vedotin Adverse Events - EP4: Hyperglycemia

June 05, 2023 14:00 - 29 minutes - 20.5 MB

Welcome to our podcast series discussing treatment-related adverse events with enfortumab vedotin in the management of urothelial carcinoma. In this fourth episode, we discuss the management of hyperglycemia associated with enfortumab vedotin, or EV. Our Guests: This fourth episode on the management of neuropathy is hosted by Dr Nimira Alimohamed, Medical Oncologist at the Tom Baker Cancer Centre, Calgary, AB and Clinical Assistant Professor in the Department of Medicine at the University o...

Podcast Series - Urothelial Carcinoma: Management of Enfortumab Vedotin Adverse Events - EP2: Skin Reactions

April 28, 2023 14:00 - 30 minutes - 20.7 MB

Welcome to our podcast series discussing treatment-related adverse events with enfortumab vedotin in the management of locally advanced or metastatic urothelial carcinoma. In this second episode, we discuss the management of skin reactions associated with enfortumab vedotin, or EV. Our Guests: In this episode, Dr. Normand Blais, who is a medical oncologist and Director of clinical research in thoracic oncology at the CHUM and adjunct professor at McGill University in Montreal, QC interview...

Podcast Series - Urothelial Carcinoma: Management of Enfortumab Vedotin Adverse Events - EP1: Introduction to EV

April 28, 2023 14:00 - 16 minutes - 11.1 MB

Welcome to our podcast series discussing treatment-related adverse events with enfortumab vedotin in the management of locally advanced or metastatic urothelial carcinoma. In this first episode, we discuss the evolution of therapy from chemotherapy to treatment with novel therapies such as enfortumab vedotin, or EV. We then focus on the key clinical trials examining the efficacy and safety of EV for the treatment of urothelial carcinoma. Our Guests: We introduce the topic in our first epis...

Podcast Series - Urothelial Carcinoma: Management of Enfortumab Vedotin Adverse Events - EP3: Peripheral Neuropathy

April 27, 2023 12:00 - 22 minutes - 15.7 MB

Welcome to our podcast series discussing treatment-related adverse events with enfortumab vedotin in the management of urothelial carcinoma. In this third episode, we discuss the management of peripheral neuroptathy associated with enfortumab vedotin, or EV. Our Guests: This third episode on the management of neuropathy is hosted by Dr Srikala Sridhar, Professor in the Department of Medicine at the University of Toronto and a Genitourinary Medical  Oncologist at the Princess Margaret Cancer...

Live from CCOLD - Treatment of CLL

April 03, 2023 17:00 - 30 minutes - 21.1 MB

In this episode of our podcast, recorded at the Canadian Conference on Lymphoproliferative Diseases (CCOLD) in Banff, Alberta, we discuss the latest updates in the treatment of CLL with Dr. Laurie Sehn, Dr. Matthew Davies, and Dr. Constantine Tam.  Our Guests: Dr. Sehn Dr Sehn is a Clinical Assistant Professor in the Department of Medicine at the University of British Columbia and Medical Oncologist at BC Cancer in Vancouver, British Columbia. Dr. Davids Dr Davids is the Director of Clini...

Live from CCOLD: Dr Davids Discusses the ALPINE Trial in CLL

March 23, 2023 12:00 - 17 minutes - 11.8 MB

In this episode of our podcast, recorded at the Canadian Conference on Lymphoproliferative Diseases (CCOLD) in Banff, Alberta, we discuss the results of the ALPINE trial with Dr. Matthew Davies. The ALPINE trial examined the efficacy and safety of zanubrutinib versus ibrutinib for the treatment of CLL. In this episode, Dr. Davids discusses the impact of the results of the ALPINE trial for clinical practice given the achievement of superior progression-free survival of zanubrutinib over ibrut...

Precision Medicine Series: Ep13: Biomarkers in Endometrial Cancer

March 13, 2023 16:00 - 35 minutes - 24.7 MB

Welcome to our 13th podcast episode in the Precision Medicine Series. In this episode, hosted by Anna Christofides,  we discuss diagnostic, prognostic and predictive biomarkers for the treatment of endometrial cancer.  Our Guests: Dr. Jessica McAlpine, a Gynaecologic Oncologist and Division Head in the Division of Gynaecologic Oncology at the University of British Columbia Dr. Mary Kinloch, a Gynaecologic Pathologist and Division Head of Pathology and Laboratory Medicine at the Universit...

Highlights from ASH: Canadian Perspective on the ALPINE Trial in CLL

December 19, 2022 14:00 - 15 minutes - 10.6 MB

Live From ASH, New Orleans: In this very special episode of our podcast, we discuss the results of the ALPINE trial with Dr. Laurie Sehn, following the dissemination of the results during the late breaking abstract session at the American Society of Hematology meeting in New Orleans.  Our Guest: Dr Sehn is a Clinical Assistant Professor in the Department of Medicine at the University of British Columbia and Medical Oncologist at BC Cancer in Vancouver, British Columbia. In this episode, Dr....

ASH Highlights - ALPINE Trial Shows Improved Efficacy and Safety Profile of Zanubrutinib vs Ibrutinib in CLL

December 13, 2022 16:00 - 14 minutes - 10 MB

Live From ASH, New Orleans: In this episode, Dr. Jennifer Brown discusses results of the phase 3 ALPINE trial, presented as a late breaking abstract at the American Society of Hematology (ASH) meeting 2022 in New Orleans, LA. Note: The ALPINE trial was published today in the New England Journal of Medicine: https://www.nejm.org/doi/full/10.1056/NEJMoa2211582. Our Guest: Dr. Jennifer Brown is the Director of the CLL Center of the Division of Hematologic Malignancies at Dana-Farber Cancer...

Emerging Treatments for Advanced, Unresectable Biliary Tract Cancer

October 07, 2022 14:00 - 14 minutes - 10.3 MB

In this episode we discuss current and emerging systemic treatments for advanced, unresectable biliary tract cancers, as well as the barriers to accessing new treatments in Canada.  Our Guest: Dr. Howard Lim is a Medical Oncologist, specializing in the treatment of gastrointestinal cancers at the BC Cancer Agency in Vancouver and Clinical Associate Professor in the Faculty of Medicine at the University of British Columbia.  This podcast episode was sponsored by AstraZeneca Canada. If you...

Precision Medicine in Oncology Podcast Series: Ep12. Biomarkers for the treatment of breast cancer

September 16, 2022 13:00 - 37 minutes - 26 MB

Welcome to our 12th episode in the precision medicine in oncology podcast series. In this episode we discuss diagnostic, prognostic and predictive biomarkers for the treatment of breast cancer. Our Guest: Our guest for this episode is Dr. David Cescon,  a Medical Oncologist and Clinician Scientist at the Princess Margaret Cancer Centre in Toronto, Ontario, where his clinical practice is devoted to the care of patients with breast cancer.   This podcast episode was sponsored by Merck Canad...

COVID-19 Pre-Exposure Prophylaxis - Ep4: Protecting Immunocompromised Patients

August 19, 2022 15:00 - 22 minutes - 15.5 MB

Welcome to IMPACT Medicom’s podcast series on COVID-19 prophylaxis. In this third episode of the series, we discuss the use of COVID-19 pre-exposure prophylaxis as a strategy to protect patients with cancer who are not able to mount a sufficient antibody response to vaccination.   Our Guest: Our guest  is Dr. Cowan, who is an Associate Scientist at The Ottawa Hospital Research Institute and Assistant Professor at The University of Ottawa. Dr. Cowan is also cross-appointed as an Assistant Pro...

COVID-19 Pre-Exposure Prophylaxis - Ep3: Patients with Cancer

August 16, 2022 13:00 - 35 minutes - 24.3 MB

Welcome to IMPACT Medicom’s podcast series on COVID-19 prophylaxis. In this third episode of the series, we discuss the use of COVID-19 pre-exposure prophylaxis as a strategy to protect patients with cancer who are not able to mount a sufficient antibody response to vaccination.   Our Guest: Our guest  is Dr. Dimas Yusuf, Medical Oncologist and specialist in general internal medicine at Pacific Specialty Care in Delta, BC. He is also the Managing Director of OncoCare Health Incorporated in V...

COVID-19 Pre-Exposure Prophylaxis - Ep2: Patients with Hematological Malignancies

July 12, 2022 13:00 - 14 minutes - 10.3 MB

Welcome to IMPACT Medicom’s podcast series on COVID-19 prophylaxis. In this second episode of the series, we discuss the use of COVID-19 pre-exposure prophylaxis as a strategy to protect patients with hematological malignancies who are not able to mount a sufficient antibody response to vaccination.   Our Guest: Our guest  is Dr Laurie Sehn, Clinical Assistant Professor in the Department of Medicine at the University of British Columbia and Medical Oncologist at BC Cancer in Vancouver, Brit...

COVID-19 Pre-Exposure Prophylaxis - Ep1: A pharmacist perspective (French)

July 07, 2022 21:00 - 21 minutes - 15.1 MB

Bienvenue dans la série de balados d’IMPACT Medicom sur la prophylaxie contre la COVID-19.   Notre invitée Notre invitée dans l’épisode d’aujourd’hui est Annick Dufour, chef adjointe au département de pharmacie du CISSS Montérégie-Centre, au Québec au niveau des soins pharmaceutiques, de la recherche clinique et de l’oncologique.  Elle est pharmacienne en oncologie depuis plusieurs années. Elle est également présidente du Comité d’évolution de la pratique des soins pharmaceutiques (CEPSP) d...

Treatment of Advanced Urothelial Carcinoma – A Discussion of EV-301

June 16, 2022 14:00 - 12 minutes - 8.94 MB

Welcome to our podcast episode on the treatment of urothelial carcinoma. In this episode, hosted by Anna Christofides, we  discuss updated results of the Phase 3 EV-301 trial, presented at ASCO 2022, that examined the efficacy and safety of Enfortumab Vedotin, or EV, versus chemotherapy in patients with previously treated locally advanced or metastatic urothelial carcinoma.  Our Guest: Our guest for this episode is Dr Nimira Alimohamed, Medical Oncologist and Clinical Associate Professor o...

Immunotherapy for Cervical Cancer

May 24, 2022 11:00 - 18 minutes - 13 MB

In this episode, we discuss immunotherapy treatment and biomarker testing for metastatic cervical cancer.  Our Guest: Dr. James Bentley is a Professor and Head of the Department of Obstetrics and Gynecology at Dalhousie University, Halifax, Canada. Dr. Bentley is Past President of the International Federation of Cervical Pathology and Colposcopy (IFCPC) and the Society of Canadian Colposcopists (SCC). He is also Past-President of the Society of Gynecologic Oncology of Canada (GOC). He serv...

Immunotherapy in HNSCC Series: Ep 3 - Role of the Medical Oncologist

May 19, 2022 15:00 - 12 minutes - 8.65 MB

In this episode of IMPACT Medicom’s podcast series on immunotherapies in Head and Neck Squamous Cell Carcinoma, we discuss the medical oncologist’s role in managing patients with HNSCC, and how immunotherapies fit in to their practice. Our Guest: Dr. Martin Smoragiewicz is a Medical Oncologist at the Odette Cancer Centre, part of Sunnybrook Health Sciences Centre in Toronto, Ontario. His clinical expertise is in Genitourinary and Head & Neck cancers and his research focuses on improving the...

Precision Medicine in Oncology: Ep.11. Selection and use of PARP inhibitors for first-line maintenance treatment in ovarian cancer

May 02, 2022 14:00 - 15 minutes - 10.9 MB

Welcome to episode 11 of our Precision Medicine in Oncology series. In this episode, we discuss the development of a pan-Canadian consensus paper on the selection and use of PARP inhibitors for first-line maintenance treatment in ovarian cancer. Our Guest: Our guest for this episode is Dr. Anna Tinker, Medical Oncologist at BC Cancer in Vancouver, Canada. Dr. Tinker is also a Clinical Associate Professor in the Department of Medicine at the University of British Columbia. This podcast epis...

Immunotherapy in HNSCC Series: Ep 2 - Perspectives from Surgical Oncology

April 25, 2022 13:00 - 14 minutes - 9.8 MB

Welcome to the second episode of IMPACT Medicom’s podcast series on Immunotherapy in Head and Neck Squamous Cell Carcinomas (HNSCC). This episode includes a discussion of: The role of the surgical oncologist in managing patients with HNSCC How immunotherapy fits into to the surgical oncologist's practice    Our Guest: Our guest is Dr. Antoine Eskander, a head and neck surgical oncologist at Sunnybrook Health Sciences Centre and Assistant professor in the department of otolaryngology at th...

Immunotherapy in HNSCC Series: Ep 1 - PD-L1 testing

April 04, 2022 14:00 - 12 minutes - 8.8 MB

Welcome to the first episode of IMPACT Medicom’s podcast series on Immunotherapy in Head and Neck Squamous Cell Carcinomas. This episode includes a discussion of: The role of the pathologist in the management of head and neck cancers  PD-L1 testing as a predictive biomarker for immunotherapy in HNSCC Improving the testing process for PD-L1   Our Guest: Our guest is Dr. Matthew Cecchini, Pathologist in the Department of Pathology and Laboratory Medicine at London Health Sciences Centre an...

Triple Negative Breast Cancer: Immunotherapies and Biomarkers

March 21, 2022 15:00 - 16 minutes - 11 MB

In this episode, we discuss the treatment of triple negative breast cancer (TNBC) with Dr. Stephen Chia. We cover: The use of immunotherapies to treat TNBC Biomarkers that can determine which patients will best respond to immunotherapies The challenges of testing for PDL-1 Our Guest: Dr. Stephen Chia is a professor in the division of medical oncology and staff medical oncologist with BC Cancer, in Vancouver. He has held many leadership roles at BC Cancer, including Head of the Division o...

Prophylaxis de la COVID-19: Protection des patients immunodéprimés - Ep5 - Introduction (Francais)

March 21, 2022 12:00 - 12 minutes - 8.37 MB

Bienvenue à la série de fichiers balados d’IMPACT Medicom sur la vaccination contre la COVID-19. Roula Drossis est l’animatrice de l’épisode d’aujourd’hui.  Dans cet épisode, nous discutons de l'immunisation contre la COVID-19 et de la façon dont nous pouvons protéger nos populations les plus vulnérables qui ne sont pas en mesure de produire une réponse anticorps suffisante à la vaccination.    Notre invité: Notre invité à l’épisode d’aujourd’hui est le Dr Alex Carignan. Le Dr Carignan es...

Pre- and Post- COVID-19 Exposure Prophylaxis: Ep4 - Hematologic Malignancies

March 14, 2022 15:00 - 18 minutes - 12.6 MB

In this podcast series on pre- and post- COVID-19 prophylaxis, we discuss immunization against COVID-19 and how we can protect our most vulnerable populations who are not able to mount a sufficient antibody response to vaccination.  In this fourth episode of the series, we discuss: Response to COVID-19 vaccines in the general population Response to COVID-19 vaccines in immunocompromised people The impact of COVID-19 on patients with hematologic malignancies The potential role of pre- an...

Pre- and Post- COVID-19 Exposure Prophylaxis: Ep3 - A Pharmacist Perspective

March 11, 2022 15:00 - 23 minutes - 16.2 MB

In this podcast series on pre- and post- COVID-19 prophylaxis, we discuss immunization against COVID-19 and how we can protect our most vulnerable populations who are not able to mount a sufficient antibody response to vaccination.  In this third episode of the series, we discuss: Response to COVID-19 vaccines in the general population Response to COVID-19 vaccines in immunocompromised people The evolution of the pharmacist's role in immunization The potential role of pre- and post- COV...

Pre- and Post- COVID-19 Exposure Prophylaxis: Ep2 - Solid Organ Transplant

March 08, 2022 14:00 - 21 minutes - 15 MB

In this podcast series on pre- and post- COVID-19 prophylaxis, we discuss immunization against COVID-19 and how we can protect our most vulnerable populations who are not able to mount a sufficient antibody response to vaccination.  In this second episode of the series, we discuss: Response to COVID-19 vaccines in the general population Response to COVID-19 vaccines in people who have received a solid organ transplantation The potential role of pre- and post- COVID-19 exposure prophylaxi...

Pre- and Post- COVID-19 Exposure Prophylaxis: Ep1 - Introduction

March 08, 2022 14:00 - 14 minutes - 10.1 MB

In this podcast series on pre- and post- COVID-19 prophylaxis, we discuss immunization against COVID-19 and how we can protect our most vulnerable populations who are not able to mount a sufficient antibody response to vaccination.  In this first episode of the series, we discuss: Response to COVID-19 vaccines in the general population Populations who have a reduced response to vaccination The difference between active and passive immunization The potential role of pre- and post- COVID-...

Pre- and Post- COVID-19 Exposure Prophylaxis: Ep1 - Introduction

March 08, 2022 14:00 - 14 minutes - 10.1 MB

In this podcast series on pre- and post- COVID-19 prophylaxis, we discuss immunization against COVID-19 and how we can protect our most vulnerable populations who are not able to mount a sufficient antibody response to vaccination.  In this first episode of the series, we discuss: Response to COVID-19 vaccines in the general population Populations who have a reduced response to vaccination The difference between active and passive immunization The potential role of pre- and post- COVID-...

Precision Medicine in Oncology: Ep.10. Biomarkers in Gastrointestinal Malignancies

February 07, 2022 15:00 - 25 minutes - 17.8 MB

In this episode of IMPACT Medicom’s Precision Medicine in Oncology podcast series, we discuss the evolving biomarker landscape in gastrointestinal malignancies and some of the advantages and challenges of implementing and accessing biomarker testing.   Our guest: Dr. Rosalyn Juergens is a medical oncologist with clinical expertise in lung and esophageal cancer. She was on the faculty at The Johns Hopkins Medical Institute from 2007-2010 until she joined the faculty at McMaster University ...

Precision Medicine in Oncology: Ep.9 DEBATE - Is PARP inhibitor maintenance therapy in first-line BRCA mutated ovarian cancer a curative-intent strategy?

January 07, 2022 20:00 - 22 minutes - 15.3 MB

Welcome to episode 9 of IMPACT Medicom’s podcast series on Precision Medicine in Oncology, the second episode in a 3-part series on ovarian cancer. This episode, hosted by IMPACT Medicom’s Sarah Doucette, features a debate on whether first-line maintenance therapy with PARP inhibitors can be considered a curative strategy in patients with advanced, BRCA-mutated epithelial ovarian cancer. Our Guests: Dr. Taymaa May Taymaa May is a surgical scientist at the University Health Network and an...

Precision Medicine in Oncology: Ep.8. Importance of BRCA testing for Advanced Epithelial Ovarian Cancer

December 07, 2021 15:00 - 20 minutes - 13.9 MB

Welcome to episode 8 of IMPACT Medicom’s podcast series on Precision Medicine in Oncology, the first in a series of episodes focusing on ovarian cancer. In this episode, we discuss the importance of BRCA testing for patients with advanced epithelial ovarian cancer and how national initiatives have helped to improve BRCA testing standards across the country. Our Guests: Dr. Janice Kwon, Gynecologic Oncologist at Vancouver Coastal Health and Vice Head and Professor in the Department of Obste...

Precision Medicine in Oncology Podcast Series: Ep7. Importance of Genetic Testing in Patients with Prostate Cancer

November 29, 2021 15:00 - 23 minutes - 16.2 MB

In this seventh episode of our podcast series on precision medicine, hosted by Anna Christofides, we discuss genomic testing in prostate cancer. Our episode focuses on the evolution and uptake of genetic testing in prostate cancer. We discuss testing for homologous recombination repair (HRR) genes and their association with prognosis and influence on treatment decisions. We also discuss somatic vs germline testing and who is responsible for ordering genomic tests.  Our guest: Our guest on t...

Precision Medicine in Oncology: Ep.6 Biomarker testing in metastatic colorectal cancer – mismatch repair and beyond

November 26, 2021 16:00 - 31 minutes - 21.9 MB

Welcome to episode 6 of IMPACT Medicom’s podcast series on Precision Medicine in Oncology. In this episode Dr. Gonzalez discusses testing methodology, particularly for mismatch repair deficiency, as well as potential emerging biomarkers for metastatic colorectal cancer. Our Guest: Dr. Raul Gonzalez is an Associate Professor of Pathology at Harvard Medical School and the Director of Gastrointestinal Pathology at Beth Israel Deaconess Medical Center in Boston, Massachusetts.  Dr. Gonzalez i...

Zanubrutinib for the Treatment of Waldenstrom's Macroglobulinemia

October 22, 2021 18:00 - 35 minutes - 24.6 MB

In this episode of our podcast, we discuss the use of zanubrutinib for the treatment of Waldenstrom’s Macroglobulinemia.  Our episode discusses data from the Phase 3 ASPEN trial, comparing the efficacy and safety of zanubrutinib with ibrutinib in these patients. Our Guests Our first guest, Dr. Constantine Tam, is a Professor of Hematology at the University of Melbourne, and Consultant Hematologist at the Peter MacCallum Cancer Centre in Melbourne, Australia. He is also the lead author on t...

Precision Medicine in Oncology: Ep.5 Precision medicine for metastatic colorectal cancer

September 27, 2021 19:00 - 22 minutes - 15.4 MB

In this episode of IMPACT Medicom’s podcast series on Precision Medicine in Oncology we discuss: ·       The current standards for molecular testing in metastatic colorectal cancer ·       The potential benefit of a Canadian guideline for molecular testing in metastatic colorectal cancer Our guest: Dr. Sharlene Gill is Professor of Medicine at the University of British Columbia and Medical Oncologist at BC Cancer in Vancouver. Dr. Gill earned her MD from the University of British Columbi...

Lung Cancer Screening: Ontario

September 02, 2021 21:00 - 33 minutes - 23.3 MB

Background Lung cancer is one of the most common cancers and is the leading cause of cancer death in Canada. (2020 Canadian Cancer Statistics)  Survival from lung cancer is poor. Three-year net survival for lung cancer decreased from 71% among those diagnosed at stage 1 to 5% among those diagnosed at stage 4. Approximately half of all lung cancer cases in Canada are stage 4 at diagnosis. (2020 Canadian Cancer Statistics)  Two clinical trials, the Dutch-Belgian screening trial (NELSON) and...

Lung Cancer Screening: Western Canada

September 02, 2021 21:00 - 25 minutes - 17.6 MB

Background Lung cancer is one of the most common cancers and is the leading cause of cancer death in Canada. (2020 Canadian Cancer Statistics)  Survival from lung cancer is poor. Three-year net survival for lung cancer decreased from 71% among those diagnosed at stage 1 to 5% among those diagnosed at stage 4. Approximately half of all lung cancer cases in Canada are stage 4 at diagnosis. (2020 Canadian Cancer Statistics)  Two clinical trials, the Dutch-Belgian screening trial (NELSON) and...

Dépistage du Cancer Du Poumon: Québec

September 02, 2021 20:00 - 30 minutes - 21.1 MB

Renseignements généraux Le cancer du poumon est l’une des formes de cancer les plus courantes ainsi que la principale cause de décès par cancer au Canada. (Statistiques canadiennes sur le cancer, 2020). Le taux de survie des patients atteints d’un cancer du poumon est faible. La survie nette à trois ans est de 71 % pour les cas diagnostiqués au stade 1, et chute à 5 % pour les cas diagnostiqués au stade 4. Au Canada, environ la moitié des cancers du poumon ont atteint le stade 4 au moment ...