Dr. Frank Beier, a professor and chair of physiology and pharmacology at the University of Western Ontario, discusses the links between genetics, biology, and OA, including how skeletal and cartilage development can provide clues to osteoarthritis, links between mechanics and biology, and how the same pathways can act in different ways in aging versus surgical models of osteoarthritis. You can find out more about Dr. Beier’s work at http://uwo.ca/physpharm/beier or follow him on twitter @BeierLab.