God places the mighty in positions to accomplish His mission but He chooses the weak in accordance with people's perspectives to confound the world's mighty. 1 Corinthians 1:27-29

27 But God chose the foolish things of the world to shame the wise; God chose the weak things of the world to shame the strong. 
28 God chose the lowly things of this world and the despised things—and the things that are not to nullify the things that are, 
29 so that no one may boast before him

God can not be mocked, God can not be taken for granted.
No one, I repeat no one is indispensable.
We are all instruments in the hand of God, chosen and designed for his glory, his will, and his pleasure.