In this episode of Genetics in your world, we speak with Dr. Richard Gomulkiewicz about the evolution of gene drive resistance. With the discovery of CRISPR-Cas systems, scientists realized that they could engineer gene drives for a number of different applications. Using alleles with an “unfair” transmission advantage, we can design gene drives to help eradicate malaria vectors, agricultural pests, or even invasive species. Check out the paper, “Evading resistance to gene drives,”which was published in the February 2021 issue of GENETICS.

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