GEN Podcasts
75 episodes - English - Latest episode: about 1 year ago - ★★★★★ - 4 ratingsGenetic Engineering & Biotechnology News (GEN) has retained its position as the premier biotech publication since its launch in 1981. GEN publishes a print edition monthly and has additional exclusive editorial content online, including news and analysis as well as webinars, videos, and polls. GEN's unique news and technology focus covers the entire bioproduct life cycle, including drug discovery, early-stage R&D, applied research (e.g., omics, biomarkers, and diagnostics), bioprocessing, and commercialization.GEN's print magazine, which also can easily be accessed online, includes feature articles on emerging technologies, product roundups, in-depth overviews from key scientific and bioindustry meetings, and industry-standard tutorials and technical articles on drug discovery, bioprocessing, and assay technologies.
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Episodes
Emerging Markets Collaborate to Succeed in Post-Pandemic World
April 11, 2023 16:24 - 18 minutes - 21.4 MBHosted on Acast. See acast.com/privacy for more information.
Breathing Oxygen Back into the Biological Conversation
February 06, 2023 17:52 - 19 minutes - 22.2 MBAs good scientific investigators, we strive to make our research more reproducible, repeatable, and translatable. These traits are ostensibly engrained in researchers from the start of their careers but often fall to the wayside in pursuit of experimental answers. Throughout this three-episode podcast series, sponsored by The Baker Company, we will weave the common thread of these essential research traits and discuss some ubiquitous techniques common to so many laboratories—focusing on areas...
Global Single-Use Network Supports Assurance of Supply
January 30, 2023 13:00 - 27 minutes - 31.4 MBSingle-use systems have been steadily climbing toward the top of the tools utilized by biomanufacturers for the commercial-scale production of critical therapeutic products. However, COVID-19 created an inflection point for this technology, generating an even greater demand that will shape the market for many years. Yet, with considerable demand comes the need to focus on the key aspects driving growth while discovering the appropriate solutions to the challenges that invariably arise when t...
Resins Address Downstream Purification Concerns
January 03, 2023 16:30 - 20 minutes - 23 MBThe demand for safe and efficacious biologics has accelerated exponentially in the past several years due to the tremendous success of some of the initial therapeutic offerings in this space. Yet, along with this increased demand comes the need for innovative solutions to improve downstream production workflows. For example, eliminating purification bottlenecks and improving overall yields from chromatography steps can significantly impact the final product’s cost. In this second episode of...
Materials Sourcing: Precautions and Improvements for Cell and Gene Therapies
December 01, 2022 16:41 - 21 minutes - 29.3 MBThe success and applications of cell and gene therapies are seemingly limitless, and economic forecasts project a compound annual growth rate of almost 40% over the next eight years. This rapid expansion is a double edge sword for biomanufacturers of cell and gene therapy products. On the one hand, the tremendous growth is excellent for business. Yet, on the flip side, biomanufacturers are faced with solving the numerous challenges of scaling-up production workflows: from raw material sourci...
Mechanistic Modeling Improves Drug Discovery Workflows and Speeds Therapeutic Development
December 01, 2022 16:38 - 23 minutes - 26.4 MBThis is the final episode in our three-part GENcast series, where we discuss the virtues of mechanistic modeling and how it can significantly impact critical decision-making points in the drug discovery process, especially as drug developers move closer toward the IND process. In our two previous podcasts, we were introduced to mechanistic modeling concepts and the basics of how they can be applied to drug discovery workflows. You can listen to the earlier podcasts with the following links: e...
Moving the Drug Pipeline Forward with Mechanistic Modeling
December 01, 2022 16:34 - 25 minutes - 29.5 MBThis is part two in our three-part GENcast series, where we discuss various aspects of the drug discovery and development process and, in particular, how advanced computational techniques like mechanistic modeling can help advance the therapeutic drug pipeline for many developers. In our initial podcast, we were introduced to mechanistic modeling concepts and the basics of how they can be applied to drug discovery workflows. In this latest GENcast, I sat down once again with Dr. John Burke, P...
Reducing Drug Discovery and Development Risk with Mechanistic Modeling
May 02, 2022 19:16 - 40 minutes - 45.8 MBThe drug discovery and development process can be an arduous endeavor. Manufacturers spend considerable resources and money chasing down potential candidate molecules to create a potential new therapeutic—often resulting in abandoning the candidate in the very later stages of development due to minor factors that might have been overlooked at the onset of the discovery process. Thankfully, there have always been those investigators who sought to merge the fields of mathematics and biology wh...
Meet the Editor-in-Chief of GEN Biotechnology: Hana El-Samad, PhD
December 17, 2021 21:45 - 42 minutes - 39.2 MBGEN Biotechnology is the new peer-reviewed journal launching in early 2022 by Mary Ann Liebert Inc. aiming to publish outstanding original research and perspectives across the biotech field. In this Q&A, GEN Biotechnology Senior Editor, Fay Lin, PhD, interviews Editor-in-Chief, Hana El-Samad, PhD, about her scientific research, outreach, and vision for the journal. Learn more about GEN Biotechnology: Website: www.genbiotechjournal.com Twitter: @GENBiotechJrnl Send editorial inquiries to...
Interrogating the Links between Genetics and Psychiatric Disorders with High Throughput Assays
December 02, 2021 21:53 - 29 minutes - 33.2 MBHosted on Acast. See acast.com/privacy for more information.
Navigating the Regulatory Terrain during Cell & Gene Therapy Production
June 09, 2021 17:53 - 17 minutes - 24.6 MBNavigating the Regulatory Terrain during Cell & Gene Therapy Production by Genetic Engineering and Biotechnology News Hosted on Acast. See acast.com/privacy for more information.
Solve Your Biotherapeutic Challenges with Help from Gene Therapy University
May 05, 2021 18:15 - 20 minutes - 27.7 MBSolve Your Biotherapeutic Challenges with Help from Gene Therapy University by Genetic Engineering and Biotechnology News Hosted on Acast. See acast.com/privacy for more information.
Engineered Therapy: Ramping Up CAR-T Biomanufacturing Goals
January 11, 2021 14:58 - 8 minutes - 8.47 MBEngineered Therapy: Ramping Up CAR-T Biomanufacturing Goals by Genetic Engineering and Biotechnology News Hosted on Acast. See acast.com/privacy for more information.
What is so different about CRISPR Founder breeding?
December 16, 2020 20:26 - 28 minutes - 39.5 MBGretchen Kusek, PhD, Associate Director Scientific Services, and Bart Smits, PhD, Manager Genetic Sciences and Compliance, discuss the key considerations when breeding gene-edited animals using CRISPR, particularly in the context of mosaicism. Hosted on Acast. See acast.com/privacy for more information.
Collaborating for Filtration Success, Virtually
December 02, 2020 17:00 - 12 minutes - 12 MBCollaborating for Filtration Success, Virtually by Genetic Engineering and Biotechnology News Hosted on Acast. See acast.com/privacy for more information.
Back to the Lab – Embracing Change
November 20, 2020 16:47 - 11 minutes - 11.2 MBBack to the Lab – Embracing Change by Genetic Engineering and Biotechnology News Hosted on Acast. See acast.com/privacy for more information.
Virtual Becomes Reality for Biopharma Vaccine Development
October 29, 2020 13:29 - 11 minutes - 11.3 MBVirtual Becomes Reality for Biopharma Vaccine Development by Genetic Engineering and Biotechnology News Hosted on Acast. See acast.com/privacy for more information.
Digital Tools Push Single-Use Technology Challenges to the Side
September 16, 2020 19:50 - 8 minutes - 11.6 MBDigital Tools Push Single-Use Technology Challenges to the Side by Genetic Engineering and Biotechnology News Hosted on Acast. See acast.com/privacy for more information.
The Quiet Voice of Immunotherapy That's Starting to Be Heard
August 24, 2020 18:19 - 17 minutes - 16 MBThe Quiet Voice of Immunotherapy That's Starting to Be Heard by Genetic Engineering and Biotechnology News Hosted on Acast. See acast.com/privacy for more information.
The Quite Voice of Immunotherapy That's Starting to Be Heard
August 24, 2020 18:19 - 17 minutes - 16 MBThe Quite Voice of Immunotherapy That's Starting to Be Heard by Genetic Engineering and Biotechnology News
Virtual Collaborations Push Pharma Forward During Pandemic
July 30, 2020 17:35 - 12 minutes - 11.8 MBWith regions of the world cycling through societal re-openings and shutdowns due to the ongoing coronavirus pandemic, pharma and life science companies are tasked with trying to find creative solutions that help keep production lines moving, as well as drive innovation forward. For instance, pharmaceutical manufacturers still need to meet critical project timelines so that patients receive the therapies they require. As such, many companies require varying levels of technical support to accom...
3D Cell Models Push Drug Discovery Screening into High Gear
July 29, 2020 20:11 - 14 minutes - 13.9 MBDavid Sorrell, PhD, from Horizon Discovery, speaks with GEN about the importance of cell models in the drug discovery process. Hosted on Acast. See acast.com/privacy for more information.
GENcast: CRISPR Screens Speed Drug Discovery Efforts for Disease Intervention
June 25, 2020 13:09 - 29 minutes - 27.2 MBGENcast: CRISPR Screens Speed Drug Discovery Efforts for Disease Intervention by Genetic Engineering and Biotechnology News Hosted on Acast. See acast.com/privacy for more information.
Impact of COVID-19 on the Life Sciences Industry
May 26, 2020 18:20 - 15 minutes - 14.4 MBImpact of COVID-19 on the Life Sciences Industry by Genetic Engineering and Biotechnology News Hosted on Acast. See acast.com/privacy for more information.
Trends in Bioprocess 4.0 and their Impact on Biomanufacturing
May 04, 2020 15:17 - 7 minutes - 7.5 MBTrends in Bioprocess 4.0 and their Impact on Biomanufacturing by Genetic Engineering and Biotechnology News Hosted on Acast. See acast.com/privacy for more information.
BioPharma 4.0
May 04, 2020 15:17 - 7 minutes - 7.5 MBBioPharma 4.0 by Genetic Engineering and Biotechnology News
GENcast: Navigating Your Lab through a Digital Transformation
March 19, 2020 16:22 - 25 minutes - 22.7 MBGENcast: Navigating Your Lab through a Digital Transformation by Genetic Engineering and Biotechnology News Hosted on Acast. See acast.com/privacy for more information.
Helping Biosimilars Emerge into Global Markets Takes a Practiced Hand
February 25, 2020 21:01 - 15 minutes - 13 MBHelping Biosimilars Emerge into Global Markets Takes a Practiced Hand by Genetic Engineering and Biotechnology News Hosted on Acast. See acast.com/privacy for more information.
Find the Right Fit when Tackling Late Stage Bioprocessing Challenges
January 08, 2020 20:11 - 10 minutes - 7.83 MBFiltration, filtration, filtration! It’s one of the critical factors to instituting a successful biomanufacturing process and often the element that gives scientists and engineers the most difficulty. Late-stage bioprocesses often require large volume manufacturing to meet supply requirements, and these increased volumes create challenging filtration operations—disrupting facility fit. Because so much is at stake for companies to generate bioproducts in short timeframes, when faced with these...
Find the Right Fit when Tackling Late Stage Bioprocessing Challenges
January 08, 2020 20:11 - 10 minutes - 7.83 MBFiltration, filtration, filtration! It’s one of the critical factors to instituting a successful biomanufacturing process and often the element that gives scientists and engineers the most difficulty. Late-stage bioprocesses often require large volume manufacturing to meet supply requirements, and these increased volumes create challenging filtration operations—disrupting facility fit. Because so much is at stake for companies to generate bioproducts in short timeframes, when faced with these...
Antibody Drug Conjugates: Manufacturing Precision Guided Therapeutics
November 18, 2019 21:12 - 14 minutes - 14 MBWhile the idea of a magic bullet that treats all maladies is a concept grounded in antiquity, antibody drug conjugates (ADCs) get a lot closer than almost any other class of drugs. The coupling of broadly cytotoxic compounds to the precision targeting of monoclonal antibodies creates a therapeutic weapon of disease destruction. Yet, as with most biotherapeutic manufacturing processes, scaling-up these compounds efficiently is never straight forward. Still, with the global ADC market prolifera...
Antibody Drug Conjugates: Manufacturing Precision Guided Therapeutics
November 18, 2019 20:37 - 14 minutes - 14 MBWhile the idea of a magic bullet that treats all maladies is a concept grounded in antiquity, antibody drug conjugates (ADCs) get a lot closer than almost any other class of drugs. The coupling of broadly cytotoxic compounds to the precision targeting of monoclonal antibodies creates a therapeutic weapon of disease destruction. Yet, as with most biotherapeutic manufacturing processes, scaling-up these compounds efficiently is never straight forward. Still, with the global ADC market prolifera...
GENcast: Welcoming a Digital Revolution in Life Science
October 18, 2019 14:56 - 17 minutes - 12.6 MBGENcast: Welcoming a Digital Revolution in Life Science by Genetic Engineering and Biotechnology News Hosted on Acast. See acast.com/privacy for more information.
Vaccinating the World One Collaboration at a Time
October 17, 2019 19:05 - 19 minutes - 18.6 MBPositive global health outcomes are often contingent on more than just great science, as knowledge sharing is also a fundamental part of achieving public health goals. With drug resistance on the rise for many pathogens once thought well managed clinically, scientists are looking toward the development of new vaccines to help reduce morbidity and mortality for many global diseases. Collaboration between academia, industry, suppliers, and government organizations is crucial for the successful ...
Vaccinating the World One Collaboration at a Time
October 17, 2019 19:05 - 19 minutes - 18.6 MBPositive global health outcomes are often contingent on more than just great science, as knowledge sharing is also a fundamental part of achieving public health goals. With drug resistance on the rise for many pathogens once thought well managed clinically, scientists are looking toward the development of new vaccines to help reduce morbidity and mortality for many global diseases. Collaboration between academia, industry, suppliers, and government organizations is crucial for the successful ...
GENcast Explore, Learn, & Collaborate On Viral Safety In Biomanufacturing
September 04, 2019 19:53 - 14 minutes - 14 MBGENcast Explore, Learn, & Collaborate On Viral Safety In Biomanufacturing by Genetic Engineering and Biotechnology News Hosted on Acast. See acast.com/privacy for more information.
GENcast: Explore, Learn, and Collaborate on Bioprocessing Challenges in China
August 27, 2019 19:01 - 10 minutes - 6.77 MBGreat symphonic music starts with the fundamental elements common to all orchestral instruments, but what separates a good symphony from a great one is not just pure talent, but the ability of the musicians to work together to create something ethereal. In most respects, science is no different. The open exchange of ideas and collaborative spirit is how science moves forward to create something impactful for society. And like great instrumentalists, scientists practice their craft every time ...
Empowering a Precision Health Movement with Kevin Hrusovsky
August 26, 2019 19:40 - 8 minutes - 8.37 MBEmpowering a Precision Health Movement with Kevin Hrusovsky by Genetic Engineering and Biotechnology News Hosted on Acast. See acast.com/privacy for more information.
GENcast Explore, Learn, & Collaborate As Next-Generation Bioprocessing Moves Toward Future Horizons
July 18, 2019 00:00 - 13 minutes - 25 MBGENcast Explore, Learn, & Collaborate As Next-Generation Bioprocessing Moves Toward Future Horizons by Genetic Engineering and Biotechnology News Hosted on Acast. See acast.com/privacy for more information.
GENcast Interview with Quanterix CEO Kevin Hrusovsky
July 15, 2019 19:28 - 9 minutes - 7.75 MBGENcast Interview with Quanterix CEO Kevin Hrusovsky by Genetic Engineering and Biotechnology News Hosted on Acast. See acast.com/privacy for more information.
Nanostring Podcast with David Rimm, MD, PhD
July 03, 2019 13:12 - 8 minutes - 6.34 MBNanostring Podcast with David Rimm, MD, PhD by Genetic Engineering and Biotechnology News Hosted on Acast. See acast.com/privacy for more information.
ATCC Podcast Final
June 11, 2019 18:20 - 31 minutes - 26.5 MBATCC Podcast Final by Genetic Engineering and Biotechnology News Hosted on Acast. See acast.com/privacy for more information.
GENcast: Explore, Learn, and Collaborate on Regulatory Challenges in Asia
March 27, 2019 20:12 - 10 minutes - 8.32 MBGENcast: Explore, Learn, and Collaborate on Regulatory Challenges in Asia by Genetic Engineering and Biotechnology News Hosted on Acast. See acast.com/privacy for more information.
GENcast: Explore, Learn, and Collaborate on Cell & Gene Therapy Manufacturing Challenges
March 06, 2019 14:40 - 18 minutes - 14.6 MBGENcast: Explore, Learn, and Collaborate on Cell & Gene Therapy Manufacturing Challenges by Genetic Engineering and Biotechnology News Hosted on Acast. See acast.com/privacy for more information.
GENcast: Explore, Learn, and Collaborate on Bioproduction Training in Asia-Pacific
February 07, 2019 15:38 - 8 minutes - 7.43 MBThey say, “good talent is hard to find!” This is especially true for emerging high-growth markets where many in the workforce lack the advanced skills necessary to aid their bioproduction needs and expand their market profile. Leveraging the success of the M Lab™ Collaboration Centers, the MilliporeSigma team was able to foster key collaborations with government agencies to provide essential hands-on training programs in various Asia-Pacific countries such as Singapore and Taiwan. In this pod...
GENcast: Explore, Learn, and Collaborate on Next-Generation Bioprocessing
December 13, 2018 18:06 - 13 minutes - 11.2 MBGENcast: Explore, Learn, and Collaborate on Next-Generation BioprocessingAs biomolecules become increasingly complex and manufacturer pipelines more diversified, scientists are searching for new ways to overcome the challenges of rapidly changing bioprocessing platforms. In this podcast, we have gathered an array of industry experts to discuss their efforts with the M Lab™ Collaboration Centers around the globe to address some of the latest developments in Next-Generation Bioprocessing.This i...
Illumina’s Acquisition of PacBio: Accelerating the Pace of Genomic Discovery
November 06, 2018 16:12 - 7 minutes - 2.42 MBGEN Sounds of Science November 5, 2018Illumina just purchased Pacific BioSciences (PacBio) for $1.2 billion. Shawn Baker formerly worked for Illumina as both a scientist and manager. He currently serves as the chief science officer for AllSeq and as a genomics startup advisor and consultant at SanDiegOmics.com. GEN asked Shawn about the significance of Illumina buying PacBio to the sequencing market and to obtain his take on what’s driving the Illumina deal? Hosted on Acast. See acast.com/p...
Streamlining the Peptide Synthesis Process
June 05, 2018 14:33 - 7 minutes - 2.85 MBGEN Sounds of Science June 1, 2018CEM Corporation Applies Advanced Microwave TechnologyCEM provides microwave instrumentation for researchers involved in analytical and synthetic chemistry. Major application areas include acid digestion for elemental analysis, compositional testing of food products, peptide synthesis, and chemical synthesis.GEN recently spoke to Michael J. Karney, CEM’s life science product manager. During a sponsored pocast, Mr. Karney described how CEM’s technologies are im...
Lentiviral Systems for Gene Delivery
May 01, 2018 14:36 - 6 minutes - 2.26 MBGEN Sounds of Science May 1, 2018GEN recently spoke to Minjun Liu, Ph.D., marketing director for OriGene, for a sponsored podcast. OriGene Technologies was founded as a research tool company focused on the creation of a large commercial collection of full-length human cDNAs in a standard expression vector. Company officials say the firm’s mission is to prepare comprehensive, genome-wide research tools and technology platforms to allow scientists to better study complete biological pathways. T...
Transforming the Bioresearch and Healthcare Industries
January 26, 2018 16:07 - 5 minutes - 4.24 MBGEN Sounds of Science January 26, 2018Technology and Data Usher in a New Age in MedicineHaving the right data and knowing how to use it will be the key to success in the healthcare market in the future. Hosted on Acast. See acast.com/privacy for more information.