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Human Organs-on-Chips
Futureproof with Jonathan McCrea
English - October 09, 2022 10:00 - 39 minutes - 36.5 MB - ★★★★★ - 11 ratingsScience radio Homepage Download Apple Podcasts Google Podcasts Overcast Castro Pocket Casts RSS feed
Previous Episode: Futureproof Extra: The End of Medicine As We Know It
Next Episode: Futureproof Extra: The science behind bees' waggle dance
Drug development is notoriously slow and expensive to bring a new compound from the lab bench to market. A major cause of this inefficiency is the traditional reliance on testing drugs in animals before they are tested in humans. Animal models often do not accurately reflect human physiology, meaning that drugs that appear to be safe and effective in animals frequently turn out to be harmful or ineffective in humans.
The solution could come from computer microchip manufacturing methods to create “Organs-on-Chips", microfluidic culture devices that recapitulate the complex structures and functions of living human organs.
Dane Gobel, the Co-Founder and Operations Director of Methuselah Foundation joins Jonathan to discuss.