FirstWord Pharma PLUS editors Matthew Dennis and Simon King discuss the potential impact of the Omicron variant on the efficacy of COVID-19 vaccines, how GlaxoSmithKline and Sanofi are making moves to keep their vaccines portfolios at the cutting edge of R&D and whether there is a meaningful future for Merck & Co.’s COVID-19 antiviral molnupiravir after this week’s close-run AdCom vote.