Episode 545: Isaac's Head

Everything To Guppy is a bite-sized, four-times weekly comedy/gaming podcast in which Gary Butterfield (Watch Out For Fireballs) and William Hughes (The A.V. Club) attempt to analyze every single item, boss, character, and concept in the rogue-lite video game The Binding Of Isaac. They manage to pull it off only slightly less than 50 percent of the time.