40: How to Engineer a Pandemic Virus

Equinox

English - January 14, 2021 00:21 - 54 minutes - 50.7 MB
Earth Sciences Science Life Sciences astronomy biology discoveries experiments historical innovation practical science research science technology Homepage Download Google Podcasts Overcast Castro Pocket Casts RSS feed

Previous Episode: 39: Science Year in Review

Next Episode: 41: Scientific Advances Thanks to COVID-19

Joseph and Rob really get into some difficult subjects on this episode as they discuss how scientists pursue their work and whether or not the COVID-19 virus was engineered in a laboratory.

Carter RW and Sanford JC (2012) A new look at an old virus: patterns of mutation accumulation in the human H1N1 influenza virus since 1918. T Bio Med Mod 9:42; doi

Sanford J, et al. (2015) The waiting time problem in a model hominin population. T Bio Med Model 12:18; doi

Anderson KG, et al. (2020) The proximal origin of SARS-CoV-2. Nature Med 26:450–452; doi

Menachery VD, et al. (2015) A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence. Nat Med 21(12):1508–1514; doi

Williams, S. (2020) NIH Cancels Funding for Bat Coronavirus Research Project, The Scientist, 28 Apr 2020

[Zhou H, et al. (2020) A novel bat coronavirus closely related to SARS-CoV-2 contains natural insertions at the S1/S2 cleavage site of the spike protein. Curr Biol 30:2196–2203; doi](10.1016/j.cub. (2020)05.023)