Industrial-scale farms known as concentrated animal feeding operations (CAFOs) have become an increasing focal point for environmental health research because of their emissions and concerns they may contribute to antibiotic resistance, adverse community impacts, and zoonotic disease outbreaks. They are also a source of political controversy in states including North Carolina and Missouri where government agencies are grappling with decisions about CAFO monitoring and permitting. In this podcast, Peter Thorne describes some of the health concerns surrounding these facilities. Thorne, director of the NIEHS-funded Environmental Health Sciences Research Center at the University of Iowa, is the lead author of an EHP mini-monograph on environmental health effects of CAFOs. Visit the podcast webpage to download a full transcript of this podcast.