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Drosophila melanogaster models for neurodegenerative diseases
15 episodes - English - Latest episode: over 5 years ago -Drosophila models of neurological disease are essential to understand complex human pathologies in many different aspects of the biomedical research. The program of the course will cover the latest achievements in Drosophila state-of-the- art methodologies aimed to the accurate representation of human disease and the design of innovative therapeutic and diagnostic approaches. The lectures will include an introduction to Drosophila neurogenetics as well as an overview of various strategies to induce cell-type specific gene expression or silencing in the nervous system. In parallel, the course will also instruct participants on how to measure synaptic functioning, perform in vivo imaging analysis, assess altered neurological behaviors and evaluate these traits in disease models.
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Episodes
G. Gilestro - Analysing and manipulating sleep in Drosophila
February 28, 2019 07:38 - 50 minutes - 573 MB VideoGiorgio Gilestro, Imperial College London, UK speaks on "Analysing and manipulating sleep in Drosophila". This movie has been recorded by ICGEB Trieste at "Drosophila melanogaster models for neurodegenerative diseases" Course, 17 - 20 April 2018, Trieste, Italy.
F. Feiguin - Neuronal and extraneuronal mechanisms of neurodegeneration in ALS
February 27, 2019 15:38 - 50 minutes - 574 MB VideoFabian Feiguin, ICGEB Trieste, Italy speaks on "Neuronal and extraneuronal mechanisms of neurodegeneration in ALS". This movie has been recorded by ICGEB Trieste at "Drosophila melanogaster models for neurodegenerative diseases" Course, 17 - 20 April 2018, Trieste, Italy.
P. Bellosta - Neuronal death and cell survival a tight balance controlled by nutrients and amino acids to keep neurons clean
February 27, 2019 15:33 - 35 minutes - 419 MB VideoPaola Bellosta, University of Trento, Italy speaks on "Neuronal death and cell survival a tight balance controlled by nutrients and amino acids to keep neurons clean". This movie has been recorded by ICGEB Trieste at "Drosophila melanogaster models for neurodegenerative diseases" Course, 17 - 20 April 2018, Trieste, Italy.
A. Megighian - Drosophila melanogaster: from neurophysiology to behavior
February 27, 2019 15:31 - 57 minutes - 691 MB VideoAram Megighian, University of Padova, Italy speaks on "Drosophila melanogaster: from neurophysiology to behavior". This movie has been recorded by ICGEB Trieste at "Drosophila melanogaster models for neurodegenerative diseases" Course, 17 - 20 April 2018, Trieste, Italy.
A. Hidalgo - The molecular mechanisms of glial regeneration and CNS repair
February 27, 2019 15:29 - 1 hour - 698 MB VideoAlicia Hidalgo, The University of Birmingham, UK speaks on "The molecular mechanisms of glial regeneration and CNS repair". This movie has been recorded by ICGEB Trieste at "Drosophila melanogaster models for neurodegenerative diseases" Course, 17 - 20 April 2018, Trieste, Italy.
A. Hidalgo - The regenerative potential of glial cells
February 27, 2019 15:28 - 56 minutes - 652 MB VideoAlicia Hidalgo, The University of Birmingham, UK speaks on "The regenerative potential of glial cells". This movie has been recorded by ICGEB Trieste at "Drosophila melanogaster models for neurodegenerative diseases" Course, 17 - 20 April 2018, Trieste, Italy.
T. Weil - The function of bimolecular condensate in translational regulation during development, pathogenesis and neurodegeneration
February 27, 2019 15:26 - 47 minutes - 544 MB VideoTim Weil, University of Cambridge, UK speaks on "The function of bimolecular condensate in translational regulation during development, pathogenesis and neurodegeneration". This movie has been recorded by ICGEB Trieste at "Drosophila melanogaster models for neurodegenerative diseases" Course, 17 - 20 April 2018, Trieste, Italy.
T. Weil - mRNA biology and local translation
February 27, 2019 15:24 - 51 minutes - 609 MB VideoTim Weil, University of Cambridge, UK speaks on "RmRNA biology and local translation". This movie has been recorded by ICGEB Trieste at "Drosophila melanogaster models for neurodegenerative diseases" Course, 17 - 20 April 2018, Trieste, Italy.
G. Gilestro - What flies can teach us about sleep?
February 27, 2019 15:12 - 47 minutes - 557 MB VideoGiorgio Gilestro, Imperial College London, UK speaks on "What flies can teach us about sleep?". This movie has been recorded by ICGEB Trieste at "Drosophila melanogaster models for neurodegenerative diseases" Course, 17 - 20 April 2018, Trieste, Italy.
A. Whitworth - Mitochondrial dysregulation in Parkinson's disease – lessons from Drosophila – part 2
February 27, 2019 15:09 - 44 minutes - 500 MB VideoAlex Whitworth, University of Cambridge, UK speaks on "Mitochondrial dysregulation in Parkinson's disease – lessons from Drosophila – part 2". This movie has been recorded by ICGEB Trieste at "Drosophila melanogaster models for neurodegenerative diseases" Course, 17 - 20 April 2018, Trieste, Italy.
A. Giangrande - From neural stem cells to glial differentiation
February 27, 2019 15:06 - 45 minutes - 506 MB VideoAngela Giangrande, USIAS, Strasbourg, France speaks on "From neural stem cells to glial differentiation". This movie has been recorded by ICGEB Trieste at "Drosophila melanogaster models for neurodegenerative diseases" Course, 17 - 20 April 2018, Trieste, Italy.
A. Whitworth - Mitochondrial dysregulation in Parkinson's disease – lessons from Drosophila – part 1
February 27, 2019 15:04 - 47 minutes - 562 MB VideoAlex Whitworth, University of Cambridge, UK speaks on "Mitochondrial dysregulation in Parkinson's disease – lessons from Drosophila – part 1". This movie has been recorded by ICGEB Trieste at "Drosophila melanogaster models for neurodegenerative diseases" Course, 17 - 20 April 2018, Trieste, Italy.
T. Vaccari - Roles of the trafficking machinery in neurodegeneration
February 27, 2019 15:02 - 54 minutes - 640 MB VideoThomas Vaccari, Università degli Studi di Milano, Italy speaks on "Roles of the trafficking machinery in neurodegeneration". This movie has been recorded by ICGEB Trieste at "Drosophila melanogaster models for neurodegenerative diseases" Course, 17 - 20 April 2018, Trieste, Italy.
A. Giangrande - Cell-Specific epigenetic signatures in the nervous system
February 27, 2019 14:57 - 41 minutes - 495 MB VideoAngela Giangrande, USIAS, Strasbourg, France speaks on "Cell-Specific epigenetic signatures in the nervous system". This movie has been recorded by ICGEB Trieste at "Drosophila melanogaster models for neurodegenerative diseases" Course, 17 - 20 April 2018, Trieste, Italy.
T. Vaccari - Regulation of autophagy in health and disease
February 27, 2019 14:57 - 56 minutes - 660 MB VideoThomas Vaccari, Università degli Studi di Milano, Italy, speaks on "Regulation of autophagy in health and disease". This movie has been recorded by ICGEB Trieste at "Drosophila melanogaster models for neurodegenerative diseases" Course, 17 - 20 April 2018, Trieste, Italy.