Before the 1960s, there was no method available to prevent Rh sensitization during Rh-incompatible pregnancies. Then, in 1968, the FDA approved the use of RhoGAM to help prevent Rh immunization. This was a landmark move in the field of Obstetrics. More recently, ever evolving data and medical genomic technology has brought new insights to RHD alloimmunization care. Can maternal RH typing be avoided with early pregnancy loss (under 12 weeks)? Why about in cases of pregnancy termination? Is that safe? And what is the UNITY non-invasive prenatal test? How can it be used to decrease unnecessary Rhogam administration? Well cover all this new data in this episode (NOTE: UNITY is not a sponsor of this podcast nor of this episode).