Transformational Pediatrics
194 episodes - English - Latest episode: about 2 months ago - ★★★★ - 4 ratingsTransformational Pediatrics features interviews with physicians and researchers at Children’s Mercy Kansas City who are transforming pediatric care through genomic medicine, personalized therapeutics, health services and outcomes research, and innovations in health care delivery.
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Episodes
Updated Dermatology Guidelines and Use of Bactrim
March 07, 2024 07:00 - 24.5 MBBactrim is a commonly prescribed antibiotic used to treat a variety of conditions, including urinary tract infections, acne and skin and soft tissue infections. The American Academy of Dermatology recently revised its guidelines discouraging the use of Bactrim to treat acne based on research conducted by my next guests – Dr. Jenna Miller, pediatric intensivist, and Dr. Jennifer Goldman, Infectious Diseases, of Children’s Mercy Kansas City.
Genomic Answers for Kids Expands Sequencing to Clinical Setting
January 19, 2024 07:00 - 27.3 MBChildren’s Mercy Kansas City, one of the nation’s leading independent pediatric health organizations, announced it is the first health care system to use 5-base HiFi sequencing, the world’s most-advanced genomic sequencing technology from PacBio, in the clinical setting to accelerate diagnoses for even more patients and families.
Precision Medicine in Pediatrics: Genetic Testing for Children with Cancer
January 19, 2024 07:00 - 39.6 MBTo accelerate precision medicine for pediatric oncology, Children’s Mercy Kansas City, together with its Research Institute (CMRI), pioneered a new whole-exome-sequencing-based genetic test for all children diagnosed with cancer. While many pediatric research institutions in the country conduct genetic sequencing of tumors, CMRI is one of the few institutions performing both research and clinical sequencing in-house on both tumor and normal DNA samples.
Navigating Pediatric Fontan-Associated Liver Disease
December 06, 2023 07:00 - 18.8 MBIncredible advances in the care of patients born with single-ventricle heart disease have led to significantly better quality of life and survival. Complex surgical palliation culminating in the Fontan procedure is effective and can allow patients to grow and develop similar to their peers. Unfortunately, changes related to Fontan anatomy lead to stress and increased pressure on the liver, known as Fontan-associated liver disease. These stresses can cause scar tissue to form and—rarely—liver...
Population Health Management and Pediatric Type 1 Diabetes
November 27, 2023 07:00 - 12.8 MBIn this episode, Dr. Mark Clements leads a discussion focusing on population health management and pediatric type 1 diabetes.
Data Science: Informing Better Health Care Decisions
May 26, 2023 05:00 - 10 MBData science -- often discussed with terms like artificial intelligence, machine learning, big data, data goverernance -- has the potential to transform every aspect of health care, from the patient experience to how, when and where care is provided, and improving outcomes. In this Transformational Pediatrics episode, Mark Hoffman, PhD, Chief Research Information Officer at Children's Mercy Kansas City, discusses the challenges and opportunities for data science within pediatric health care ...
Professional Coaching in Medicine and Health Care
May 24, 2023 06:00 - 15 MBThe health care sector has begun to embrace coaching to promote resilience and innovation during a time of massive disruption while also cultivating healthier workplace cultures. In this podcast, Alyssa Stephany, MD, Director of the Physician Leadership Center at Children's Mercy Kansas City shares how professional and peer coaching can help reduce burnout, increase job satisfaction, and improve the overall provider experience of health care, while also having a positive effect on patient ca...
Health and Poverty
July 18, 2022 06:00 - 12.9 MBNearly 1 in 5 children in the United States live in rural areas. Rural children experience health and health care disparities compared to their urban peers and represent a unique and vulnerable pediatric patient population. Important disparities exist in all-cause mortality, suicide, firearm-related unintentional injury, and obesity. In this episode, Dr. Jessica Bettenhausen discusses research into these disparities, their causes and potential actions to address them.
Health and Poverty of Rural Children
July 18, 2022 05:00 - 12.9 MBNearly 1 in 5 children in the United States live in rural areas. Rural children experience health and health care disparities compared to their urban peers and represent a unique and vulnerable pediatric patient population. Important disparities exist in all-cause mortality, suicide, firearm-related unintentional injury, and obesity. In this episode, Dr. Jessica Bettenhausen discusses research into these disparities, their causes and potential actions to address them.
Three Surprising Lessons from the Genomic Revolution in Pediatrics
September 20, 2021 05:00 - 11.9 MBChildren's Mercy Kansas City has been at the forefront of implementing genomic sequencing in clinical pediatrics and neonatology. In this podcast, John Lantos, MD, Director of Pediatric Bioethics at Children's Mercy Kansas City, discusses the promise of genomic medicine and three suppressing lessons we have learned about the role of genomic medicine for diagnosing, the response of parents, and how testing is impacting care.
Health Care Informatics
May 28, 2021 05:00 - 14.4 MBWhat is informatics and why is it important in health care? Listen as Jill Westcott, MD, MS, FACOG, Physician Informaticist for the Fetal Health Center at Children's Mercy, shares her expertise on the topic and how informatics is improving patient outcomes in fetal health.
Genomic Answers for Kids Establishes New Paradigm in Rare Disease Research
May 10, 2021 05:00 - 9.28 MBThe Children’s Mercy Research Institute® is undertaking a research initiative to build a first-of-its-kind pediatric data repository to facilitate the search for answers and novel treatments for pediatric genetic conditions. Our goal is to collect genomic data and health information for 30,000 children and their families over the next seven years, creating a database of nearly 100,000 genomes.
Transforming Pediatric Research
March 10, 2021 06:00 - 11.6 MBHow do we create a healthier future for children? The Children's Mercy Research Institute with a core focus on genomics, personalized therapeutics, population health, health care innovation and bioethics is positioned to fundamentally transform pediatric research and create a world of well-being for all children. Listen as Thomas Curran, PhD, FRS, Chief Scientific Officer, discusses the institute and the future of pediatric research.
EMS Timely Tips: Autism Spectrum Disorders
March 08, 2021 08:00 - 12.3 MBAutism is one of the fastest growing developmental disability’s in the United States, effecting approximately 1 in 54 births. For the safety of emergency medical providers and patients with developmental disabilities, it is important to understand what Autism is and how to care for pediatric patients diagnosed with it. In this segment, Children’s Mercy specialists will discuss common misconceptions about Autism Spectrum Disorder, as well as share insight from a memorable EMS encounter involvi...
Pediatric Hemodialysis and Advances in Infection Prevention and Vascular Preservation
February 16, 2021 06:00 - 8.49 MBTo reduce the risk of complications related to hemodialysis, the Children’s Mercy Kansas City Division of Nephrology has implemented several strategies. Listen as Dr. Bradley Warady shares how the institution of standardized infection prevention practices has resulted in more than 1,200 consecutive days without an outpatient central line-associated blood stream infection (CLABSI) in a hemodialysis (HD) patient. In addition, Dr. Warady discusses how vascular preservation protocols also are imp...
Achieving Transplant Excellence Through Personalized Medicine
February 16, 2021 06:00 - 8.5 MBChildren’s Mercy Kansas City is recognized as one of the top 10 nephrology programs in the nation by U.S. News & World Report, and the kidney transplant program has incorporated a number of innovative practices into their management plan that are designed to enhance patient outcomes. Join us as Dr. Bradley Warady discusses how the program’s personalized approach to meeting each patient’s unique needs — including repeated surveillance biopsies, epitope matching and pharmacokinetic assessment o...
Impact of Race & Ethnicity on Responses to Folic Acid Dosing
January 05, 2021 06:00 - 10.9 MBDevika Maulik MD shares her translational research as it relates to folic acid and different responses to dosing among women of various races and ethnicities. She is using the information gathered to create recommended guidelines for folic acid dosing. She discusses current literature on this topic, as well as her studies in this area.
Pediatric Recurrent Intentional Foreign Body Ingestion: Case Series and Review of the Literature
November 05, 2020 16:00 - 27.5 MBDr. Christina Low Kapalu discusses cases and literature surrounding pediatric recurrent intentional foreign body ingestion.
Variations in Morning Serum Cortisol Levels Based on Sex and Pubertal Status
September 11, 2020 05:00 - 13.9 MBDr. Sarah Tsai discusses his recent findings from his study surround serum morning cortisol levels.
Twin to Twin Transfusion Syndrome: Algorithm for Diagnosing and Treating
July 31, 2020 05:00 - 19 MBDr. Emanuel "Mike" Vlastos discusses the algorithm for diagnosing and trading twin to twin transfusion syndrome.
Improved Outcomes for Liver Transplantation with Biliary Atresia
June 18, 2020 05:00 - 11.6 MBDr. James Daniel discusses improved outcomes for liver transplantation with Biliary Atresia.
Clinical Characteristics of Fractures in Pediatric Patients Exposed to PPIs
May 15, 2020 16:30 - 11.5 MBDr. Nathan Fleishman discusses the clinical characteristics of fractures in pediatric patients exposed to PPIs.
Partnering Together to Treat ADHD
May 15, 2020 06:00 - 11.4 MBADHD is among the most common neurodevelopmental disorders of childhood; with treatments including behavior therapy and medication. In this podcast, Carla Allan, PhD will help you learn more about the Attention Deficit-Hyperactivity Disorder Specialty Clinic at Children’s Mercy, which provides expert care for children ages 6-12 who have problems with attention and impulse control issues, and find out how to refer your patients.
Transformational Pediatrics: Pediatric Provider Well-Being and the COVID-19 Pandemic
April 30, 2020 06:00 - 11.4 MBThe COVID-19 pandemic has created an unprecedented work environment for pediatricians and pediatric subspecialists. How we practice medicine has been dramatically changed. When discussing physical precautions such as PPE and social distancing, provider mental well-being also should be a part of the conversation. In this podcast, Jennifer Bickel, MD, pediatric neurologist and Medical Director of the Children’s Mercy Center for Professional Well-Being, discusses how pediatricians have respond...
Pediatric Provider Well-Being and the COVID-19 Pandemic
April 30, 2020 05:00 - 11.4 MBThe COVID-19 pandemic has created an unprecedented work environment for pediatricians and pediatric subspecialists. How we practice medicine has been dramatically changed. When discussing physical precautions such as PPE and social distancing, provider mental well-being also should be a part of the conversation. In this podcast, Jennifer Bickel, MD, pediatric neurologist and Medical Director of the Children’s Mercy Center for Professional Well-Being, discusses how pediatricians have respond...
Transformational Pediatrics: Preventing Type 2 Diabetes
April 22, 2020 06:00 - 11.1 MBDr. Kelsee Halpin discusses Endocrinology and Diabetes.
Preventing Type 2 Diabetes
April 22, 2020 05:00 - 11.1 MBDr. Kelsee Halpin discusses Endocrinology and Diabetes.
Pediatrics in Practice: Beta-lactam Antibiotic Allergies
January 03, 2020 08:00 - 13.7 MBWhile approximately 10% of US adults and children claim a penicillin allergy, only 1/20 with a reported allergy are truly allergic. Additionally, 80% of patients with IgE mediated penicillin allergy lose sensitivity after 10 years. It is important to clarify and de-label patients to ensure they receive standard of care, avoid other adverse drug reactions and have a lowered risk of clinical failure. This practice also results in cost savings. Amol Purandare, MD explains the de-labeling proce...
What Not To Miss in Pediatric Radiology
December 31, 2019 16:00 - 14.2 MBDr. Grace Mitchell discusses the latest pediatric radiology trends and technology.
Pediatrics in Practice: Addressing Anxiety and Depression in Teens
December 31, 2019 16:00 - 10.7 MBDr. Shayla Sullivant shares warning signs of anxiety and depression in teens, how to talk to your teen about their feelings, and when you should seek professional help.
Pediatrics in Practice: Bellyaches, Bowels and Barfs
December 13, 2019 16:00 - 14.5 MBThe most common reasons that children are seen by pediatric gastroenterologists relate to their bellyaches, bowels, and barfs. A simple approach to these disorders can guide general practitioners to help families find relief from these distressing symptoms.Dr. John Rosen explains when you might want to take your child to see a pediatric gastroenterologist, what to expect at an appointment, and treatments to common GI issues.
Pediatrics in Practice: Acute Evaluation of Sports injuries and What to Do in the Office
July 31, 2019 14:00 - 13.2 MBSports related injuries are on the rise with increasing child and adolescent participation. Many training programs do not cover how to evaluate and treat these patients in the subacute setting. Listen as Donna Pacicca, MD, Orthopedic Surgeon and Sports Medicine specialist with the Sports Medicine Center at Children’s Mercy Kansas City, discusses evidence-based best practices for pediatric patients with sports related musculoskeletal injuries. Dr. Pacicca will discuss how to take a good histo...
Bariatric Surgery
July 16, 2019 13:00 - 17.6 MBChildhood Obesity continues to be on the rise and causes serious health consequences. In this podcast, Dr. Jason Fraser discusses the Bariatric Surgery program at Children's Mercy. We learn who is a candidate for bariatric surgery, the requirements for surgery, why Children's Mercy decided to offer bariatric surgery, the type of bariatric surgery offered at Children's Mercy and results.
Pediatrics in Practice: What and When to Refer to Pediatric and Adolescent Gynecology
June 03, 2019 14:00 - 9.5 MBFemale reproductive health is critical in growing girls and young women. Julie Strickland, MD, Section Chief of Pediatric and Adolescent Gynecology, joins us for this episode of Pediatrics in Practice to talk about the need for pediatric and adolescent gynecologists, the conditions they treat and when to refer.
Pediatrics in Practice: Dysmenorrhea
June 03, 2019 14:00 - 11.1 MBDysmenorrhea is the most common gyencologic complaint in adolescent females, affecting more than half of this population. Julie Strickland, MD, Section Chief of Pediatric and Adolescent Gynecology at Children's Mercy, discusses causes, diagnoses and treatment of this painful condition.
Polycystic Ovary Syndrome: Current Concepts for A Complex Condition
May 28, 2019 11:00 - 10.8 MBDr. Tania Burgert discusses Polycystic Ovary Syndrome (PCOS) and the current ideas surrounding a complex condition.
Pediatrics in Practice: Pediatric Enuresis
March 27, 2019 14:00 - 12.9 MBEnuresis or bedwetting is a common childhood problem, affecting 5 to 7 million children in the United States each year. By age 7, about 5-10 percent of all children are still wet at night. While 15 percent of kids will outgrow bedwetting without intervention every year, waiting and watching to see what happens could delay children getting dry at night. Listen as Judith VanSickle, MD, Pediatric Nephrologist, discusses causes, diagnosis and treatment of enuresis.
Pediatrics in Practice: Pediatric Uveitis
February 26, 2019 16:00 - 9.08 MBSo you think rheumatology is all about joint pain? Think again. Rheumatologists treat a wide array of autoimmune conditions affecting nearly every part of the body- even the eyes. Uveitis is an inflammatory eye condition that can be caused by infection, underlying autoimmune diseases such as juvenile arthritis or sarcoidosis, or as an idiopathic disease. Untreated it can lead to cataracts, glaucoma and even blindness. Listen as Ashely Cooper, MD, pediatric rheumatologist, discusses childhood ...
How the Cardiac High Acuity Monitoring Program (CHAMP) is Helping Change Lives
January 14, 2019 13:00 - 8.6 MBCHAMP (Cardiac High Acuity Monitoring Program) is a multi-disciplinary based team that has been designed to meet the needs of the most complex cardiac population with single ventricle heart disease. The program closely monitors patients with single ventricle heart disease between the critical first and second stages (before stage II Glenn surgery). The team at the Ward Family Heart Center at Children's Mercy has also developed a tool that makes it easier for families to report their single ve...
Pediatrics in Practice: Lean In: Addressing Teen Suicide Risk When Nobody Trained You For This
January 02, 2019 16:00 - 12.4 MBDr. Shayla Sullivant discusses warning signs of suicide in teens, and how address it with patients.
Transformational Pediatrics: CKiD Expansion
January 02, 2019 16:00 - 11.2 MBThe CKiD study was recently approved for an additional five years and $4.7 million of funding, making 20 consecutive years of funding. Historically, when participants developed end-stage disease, they left the study. The next phase of study will focus on the entire spectrum of the disease, starting with early CKiD in infants and following those who progress to kidney failure, requiring dialysis and transplant. Currently, CKiD is enrolling an additional 190 children in the new cohort. The stud...
CKiD Expansion
January 02, 2019 14:00 - 11.2 MBThe CKiD study was recently approved for an additional five years and $4.7 million of funding, making 20 consecutive years of funding. Historically, when participants developed end-stage disease, they left the study. The next phase of study will focus on the entire spectrum of the disease, starting with early CKiD in infants and following those who progress to kidney failure, requiring dialysis and transplant. Currently, CKiD is enrolling an additional 190 children in the new cohort. The stud...
Transformational Pediatrics: Targeted Therapy to Reduce Relapse of Pediatric Leukemia
December 10, 2018 16:00 - 10.2 MBPatients that have residual leukemia stem cells after chemotherapy and other treatments have substantially higher risk for relapse. Survival rates for relapsed leukemia are very poor. Even when patients survive long-term, the very toxic anti-cancer treatments are escalated in treating relapsed leukemia. This particularly risks long-term health and substantially increases the risk of early death due to side-effects of the treatment itself. John Perry, PhD, faculty member of the Children's Re...
Pediatrics in Practice: Influenza, Test or Treat?
December 10, 2018 16:00 - 10.4 MBEvery year, influenza causes many people to become ill. All children 6 months and age and older should receive a yearly flu vaccine. Vaccination remains the best way to prevent influenza. Symptoms of influenza include abrupt onset of fever, myalgias, headache, nonproductive cough, sore throat and runny nose. Fever and cough are the two most common symptoms. When presented with these symptoms, providers are faced with the question to test and confirm the diagnosis of influenza or to initiate i...
Targeted Therapy to Reduce Relapse of Pediatric Leukemia
December 10, 2018 14:00 - 10.2 MBPatients that have residual leukemia stem cells after chemotherapy and other treatments have substantially higher risk for relapse. Survival rates for relapsed leukemia are very poor. Even when patients survive long-term, the very toxic anti-cancer treatments are escalated in treating relapsed leukemia. This particularly risks long-term health and substantially increases the risk of early death due to side-effects of the treatment itself. John Perry, PhD, faculty member of the Children's Re...
Identifying Novel Drug Treatment Options for Pediatric Osteosarcoma
November 19, 2018 14:00 - 6.09 MBOsteosarcoma is highly metastatic and drug-resistant cancer. The survival rate for metastatic osteosarcoma remains less than 20 percent for the last 40 years. Tomoo Iwakuma, MD, PhD, is leading research focused on the elucidation of mechanisms underlying osteosarcoma progression and the discovery of novel drugs against this osteosarcoma. His laboratory has identified a lead compound that specifically killed canine and human osteosarcoma cells lacking the activity of the tumor suppressor p53, ...
Developmental Screening: Navigating the Pediatrician Visits
November 02, 2018 14:00 - 7.87 MBThe AAP recommends conducting general developmental screening at 9, 18, and 30 months, or whenever a concern is expressed. In addition, autism-specific screening is recommended at ages 18 and 24 months of age. When families arrive for their child's well-visits, how can each pediatrician be sure the right screening is taking place to identify any developmental delays quickly and effectively? Hear from Cy Nadler, Phd, and Sarah Nyp, MD, as they discuss the screening process and how to navigate ...
Management and Treatment for Peutz-Jeghers Syndrome
November 01, 2018 13:00 - 11.6 MBPeutz-jeghers syndrome (PJS) is an inherited syndrome, characterized by the development of gastrointestinal polyps and characteristic mucocutaneous freckling. Individuals that present with PJS tend to have polyps often in their small intestine as well as their stomach and large intestine. Recently the European Society for Pediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) group published the first set of guidelines in treating PJS in pediatric patients. Hear from Thomas Attard MD,...
Pediatrics in Practice: Common Kidney Conundrums
September 23, 2018 14:00 - 5.02 MBEnuresis, hematuria and proteinuria are common pediatric kidney disorders, but the when do these problems warrant a referral to a pediatric nephrologist? What red flag symptoms require more urgent consultation and evaluation? New specialty-specific guidelines from the "Choosing Wisely" campaign were just released for pediatric nephrology in an effort to educate about unnecessary medical tests, treatments and procedures. In this podcast, Darcy Weidemann, MD, pediatric nephrologist at Children'...
Pediatrics in Practice: Positive Antinuclear Antibody: What Now?
August 19, 2018 14:00 - 10.5 MB“Positive ANA” is one of the most common reasons for referral to the pediatric rheumatology clinic. The antinuclear antibody (ANA) is often mistakenly considered a good screening test for rheumatic disease. Dr. Ashley Cooper, Interim Division Director of Pediatric Rheumatology, discusses what it means when a child has a positive anti-nuclear antibody test, when ANA should be checked, and how to talk about the test results with the family.