IMPLANTING HUMAN BRAIN ORGANOID INTO RATS - DR. ISAAC CHEN- NEUROSUGEON: THE CHEN LABORATORY

#neuroscience #healthcare #health
Dr. Isaac Chen is an Assistant Professor in the Department of Neurosurgery at the University of Pennsylvania. He is also the Section Chief of Neurosurgery at the Philadelphia Veterans Affairs Medical Center. He obtained his undergraduate degree in Biochemical Sciences from Harvard University. Subsequently, he completed medical school and neurosurgical residency at the University of Pennsylvania. His clinical interests include functional neurosurgery, epilepsy surgery, traumatic brain injury, and brain tumors (especially those in eloquent cortex). As a surgeon and a scientist, Dr. Chen's primary focus is the preservation and restoration of brain function.
The Chen Laboratory works to "develop novel methods for restoring the function of the brain after it has been damaged by combining aspects of stem cell biology, neural tissue engineering, and neural interface technologies.
Prof Chen is the Member of
Center for Brain Injury and Repair
Institute of Regenerative Medicine
Institute for Translational Medicine and Therapeutics
Center for Neuroengineering and Therapeutics.

Dr Chen & researchers at the University of Pennsylvania have been working on Brain Organoids & have found that human-derived brain organoids can integrate into the visual cortex of rat brains. After three months, the organoids demonstrate electrical responses to visual stimuli.
The term “organoid” encompasses 3D cell culture systems that can be derived from stem cells, tumors, tissue explants, stem cells or other progenitor cells. Organoids “self-organize” under specific, controlled conditions, resembling the anatomy, physiology and complexity of organs or other body structures in a dish.

https://www.med.upenn.edu/apps/faculty/index.php/g275/p35031https://www.linkedin.com/in/isaac-chen-3051035

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