The game was played on November 20, 2022, at Mosaic Stadium in Regina, Saskatchewan. It marked the fourth Grey Cup game to be held in Regina, and the first to be held at the new Mosaic Stadium as opposed to Taylor Field. The game was played between the West Division champion Winnipeg Blue Bombers and the East Division champion Toronto Argonauts; the Argonauts won 24–23 and earned their league-leading 18th Grey Cup, preventing the Blue Bombers from becoming the first team to win three consecutive Grey Cups since 1980.