CCO Infectious Disease Podcast
383 episodes - English - Latest episode: 14 days ago -Weekly updates on new data and best practices in patient care for a variety of infectious diseases including COVID-19, HIV, and viral hepatitis, from Clinical Care Options. Gain practical strategies and earn CME/CE credit for selected episodes.
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Episodes
Beyond Viral Suppression: A Case Study Addressing Internalized HIV Stigma
April 11, 2024 15:10 - 12 minutes - 11.5 MBIn this episode, Gregory Huhn, MD, MPHTM, uses a case study to explore the reasons healthcare professionals and people living with HIV may want to further optimize ART in the setting of viral suppression. To determine the best outcome for this case study, Dr Huhn discusses the reasons individuals may not be satisfied with daily oral ART and examines data to suggest that, for some individuals with virologic suppression, switching to long-acting ART may address internalized HIV stigma. Fina...
Linkage to Care After HBV Diagnosis: Sharing Session 3
April 10, 2024 15:20 - 16 minutes - 15.6 MBIn this episode, Maria Buti, MD, and her patient discuss opportunities to optimize care for people living with hepatitis B virus (HBV), including: Barriers to HBV screening, including patient- and provider-specific barriers (eg, lack of education, failure to disclose or discuss risk factors, perceived low risk, stigma) Applying CDC recommendations for universal HBV screening in adults Strategies to improve HBV transitions of care (eg, improved education, simplify criteria for screening ...
Key HIV Studies From CROI 2024 Influencing Clinical Practice
March 29, 2024 15:09 - 44 minutes - 40.8 MBIn this episode, Joseph J. Eron, Jr., MD, and Monica Gandhi, MD, MPH, discuss the key HIV studies from CROI 2024 that are influencing their clinical practice, including: New data surrounding long-acting ART, including: The CARES study of LA CAB + RPV in a Sub-Saharan African population using a public health approach The IMPAACT 2017 MOCHA study evaluating switching to LA CAB + RPV in adolescents living with HIV The ACTG A5359 LATITUDE study of LA CAB + RPV in people with adherence challe...
How to Implement Earlier Hepatitis B Treatment
March 26, 2024 18:30 - 21 minutes - 19.7 MBIn this episode, Mark S. Sulkowski, MD, FIDSA, FAASLD; Tatyana Kushner, MD, MSCE; Paul Y. Kwo, MD; and patient advocate Jacki Chen, PhD, consider barriers and solutions for more expansive HBV treatment in the United States. Topics include: Patient subgroups to consider for treatment outside guideline criteria Adverse event and cost-effectiveness considerations Integration of patient perspectives in wider treatment Presenters: Mark S. Sulkowski, MD, FIDSA, FAASLD Professor of Medicine Di...
Empowering Patients With Education on HBV: Sharing Session 2
March 11, 2024 19:03 - 16 minutes - 15.5 MBIn this episode, Robert Wong, MD, MS, and a patient discuss opportunities to optimize care for people living with hepatitis B virus (HBV), including: Opportunities to improve patient education, including education for expectant mothers with HBV Potential cultural considerations that may result in delayed HBV diagnosis and care Stigma reduction with universal HBV screening and vaccination Strategies to improve patient education (eg, online resources, advocacy groups, use of layman’s term...
Switching HIV ART in Older People With Weight Gain and Cardiovascular Comorbidities
March 08, 2024 14:35 - 14 minutes - 13.5 MBListen to Roger Bedimo, MD, MS, FACP, discuss considerations for older people living with HIV, including: Polypharmacy and deprescribing The risk of cardiovascular events with various ART regimens Approaches for managing weight gain Presenter: Roger Bedimo, MD, MS, FACP Professor of Medicine Interim Director, Office of Global Health UT Southwestern Medical Center Chief, Infectious Diseases Section VA North Texas Health Care System Dallas, Texas Get access to all of our new podcasts by ...
Optimizing ART in Priority Populations: Initiating ART in Transgender Women
March 04, 2024 15:06 - 12 minutes - 11.5 MBIn this episode, Dr. Bedimo discusses best practices for individualized care in transgender women living with HIV, including: Providing services in a gender-affirmative care model Proactive counseling on drug-drug interactions with gender-affirming hormone therapy Strategies to reduce adverse events Presenter: Roger Bedimo, MD, MS, FACP Professor of Medicine Interim Director, Office of Global Health UT Southwestern Medical Center Chief, Infectious Diseases Section VA North Texas Health ...
COVID-19 Case Challenges: Employing Outpatient Antivirals and Addressing Drug‒Drug Interactions
February 27, 2024 22:11 - 34 minutes - 31.7 MBIn this episode, Renslow Sherer, MD, and Trinh P. Vu, PharmD, BCIDP, discuss how to optimize the use of COVID-19 antivirals and how to navigate drug-drug interactions between COVID-19 treatments and a patient’s home medications. Their discussion includes: Current COVID-19 landscape COVID-19 testing and vaccination recommendations Treatment guidelines and antiviral options for nonhospitalized adults with COVID-19 Resources for assessing and managing COVID-19 antiviral-related drug-drug in...
New Audio Updates: CCO Independent Conference Coverage of Hepatitis B at AASLD 2023
February 05, 2024 14:59 - 37 minutes - 34.2 MBIn this episode, Nancy Reau, MD, discusses new data on hepatitis B virus presented at AASLD 2023, including: Current therapies Studies 108 and 110: Factors Linked With Lack of Virologic Suppression After 8 Yr of TAF or TDF Kaiser Permanente Northern California: HCC or Death With TDF vs ETV for Chronic Hepatitis B Early vs Late Postpartum Cessation of TDF Initiated for Prevention of Vertical HBV Transmission Investigational functional cure strategies B-Together: Sequential Bepirovirsen ...
Reconsidering Your Approach: Strategies to Support PrEP Persistence and Reengagement
January 31, 2024 13:42 - 27 minutes - 24.8 MBIn this episode, LaRon E. Nelson, PhD, RN, FNP, FNAP, FNYAM, FAAN, discusses the role that healthcare professionals (HCPs) may be playing in their patients’ pre-exposure prophylaxis (PrEP) persistence and strategies to modify their approach to encourage persistence, from Clinical Care Options (CCO), including: Racial disparities in the PrEP care continuum Consideration that PrEP persistence may be less about relationship to the drug than the environment Examples of HCP implicit bias regar...
My Journey With HBV and HDV: Sharing Session 1
January 24, 2024 16:02 - 15 minutes - 14.1 MBIn this episode, Nancy Reau, MD, and her patient discuss opportunities to optimize care for people living with hepatitis B virus and hepatitis delta virus, including: The importance of patient education along the care continuum Ensuring smooth transitions of care and communication between medical teams Screening hepatitis delta in persons with chronic hepatitis B Managing hepatitis delta, including considerations for clinical trials Promoting patient advocacy Presenter: Nancy Reau, M...
Why I Started and Why I Stayed on HIV PrEP
January 12, 2024 14:30 - 6 minutes - 5.78 MBIn this episode, David Saunders discusses the value of nonstigmatizing discussions between people using HIV pre-exposure prophylaxis (PrEP) and healthcare professionals, including: Encouraging accountability to individualize adherence strategies and improve persistence to PrEP Reducing stigma, discrimination, and prejudice in healthcare settings to foster PrEP persistence Faculty: David Saunders PrEP User and Advocate Link to full program: https://bit.ly/3ZlICsL To automatically g...
Long-Acting PrEP: Strategies to Support PrEP Persistence and Reengagement
January 10, 2024 19:21 - 29 minutes - 27.3 MBIn this episode, Sarah M. Wood, MD, MS, discusses data and recommendations for long-acting pre-exposure prophylaxis (PrEP) as a strategy to support PrEP persistence and engagement for adolescents, including: The PrEP care continuum for adolescents System barriers to PrEP coverage and privacy concerns for adolescents The benefits and challenges of same-day PrEP initiation and real-world data to support it Interventions to support PrEP persistence PrEP options for different populations a...
RSV Vaccines in Adults: A Risk-Based Approach
December 27, 2023 19:17 - 9 minutes - 8.95 MBIn this episode, Angela Branche, MD, discusses RSV vaccines in older adults, including: Current Advisory Committee on Immunization Practices recommendations Risk factors associated with severe RSV disease, including RSV-related hospitalizations Approach to stratifying risk factors (eg, age, comorbidities) in determining which adults may benefit from the RSV vaccine Ongoing research on RSV vaccines in younger adults (eg, aged 40s and 50s years) with chronic comorbidities Health dispar...
How to Implement Earlier Hepatitis B and Hepatitis Delta Screening
December 22, 2023 05:00 - 27 minutes - 25.7 MBIn this episode, Douglas Dieterich, MD, leads a panel discussion with Camilla S. Graham, MD, MPH, and Robert Wong, MD, MS, to consider advantages and barriers to universal screening for chronic HBV infection and universal HDV screening in adults with HBV in the United States. Topics include: Updated CDC recommendations for one-time universal screening for HBV Addressing patient-, provider-, and system-level barriers to universal HBV screening Best practices for implementation of HDV scree...
Q&A on HIV PrEP: Episode 7 for Advanced Practice Providers
December 21, 2023 20:35 - 28 minutes - 25.8 MBIn this episode, Tavell L. Kindall, PhD, DNP, ARNP, FNP-BC, AACRN, AAHIVS, FAANP, and Anne Teitelman, PhD, FNP-BC, FANNP, FAAN, discuss key PrEP considerations for advanced practice providers in primary care settings, including: The importance of having PrEP navigators to help with logistics and be a point of contact for patients Where to find education and resources to familiarize yourself with PrEP and its prescribing Safety considerations and adverse events associated with PrEP optio...
Mental Health Challenges: Dialogues on Optimizing Engagement in HIV Care
December 20, 2023 05:00 - 43 minutes - 40.5 MBIn this podcast episode, Mark Brennan-Ing, PhD, and Nina I. Martinez discuss mental health challenges in people living with HIV and much-needed strategies to overcome these challenges to optimize engagement in HIV care, including: The increased rates of mental health disorders and substance use among people living with HIV How mental health disorders contribute to challenges with adherence to HIV treatment and engagement in care How social isolation and stigma can affect outcomes despite ...
Starting ART: Dialogues on Optimizing Engagement in HIV Care
December 18, 2023 19:37 - 42 minutes - 39.1 MBIn this podcast episode, Isolde Butler, MD, MPH, a healthcare professional caring for people living with HIV, and Marissa Gonzalez, an individual living with HIV, discuss strategies to improve healthcare professionals’ competencies in delivering optimal HIV care from the start to better support patients in overcoming barriers to sustained care engagement. The topics they discuss include: An introduction to the guidelines on ART initiation—start quickly and choose the therapy that is effec...
Engagement in Care: Dialogues on Optimizing Engagement in HIV Care
December 18, 2023 18:09 - 30 minutes - 27.6 MBIn this podcast episode, Babafemi Taiwo, MBBS, and Vincent Crisostomo discuss the evolving treatment landscape for aging people living with HIV, encompassing the clinical and external resources necessary to support physical and psychosocial health. The topics discussed include: • Mindful prescribing and understanding the impact an HIV diagnosis can have on one’s mental health, including social isolation • How to address patients’ needs and establish a trusting relationship within the confi...
Providing Options for PrEP Reengagement: Strategies to Support PrEP Persistence and Reengagement
December 15, 2023 05:00 - 16 minutes - 14.9 MBIn this episode, Kevin Astle, PharmD, BCPS, BCACP, AAHIVP, CDCES, discusses data and recommendations for providing HIV prevention options as a strategy to support PrEP persistence and engagement, including: Postexposure prophylaxis (PEP) recommendations and the data for PEP-in-Pocket Offering PrEP to everyone who receives PEP Currently recommended PrEP options and the safety and adverse event considerations with each option Monitoring recommendations for the different PrEP options The ...
Selected FXR Agonist PBC Studies: Conference Coverage of AASLD
December 13, 2023 17:52 - 17 minutes - 16.2 MBDuring the 2023 American Association for the Study of Liver Diseases conference, exciting and important results from many primary biliary cholangitis (PBC) clinical trials were reported, including 3 late-breaking studies on the PPAR-δ agonist seladelpar, the dual PPAR agonist elafibranor, and the combination of the FXR agonist obeticholic acid and a fibrate. In this episode, Kris V. Kowdley MD, FAASLD, FACP, FACG, discusses topline results from several of these studies and more, including: ...
PrEP Talks: Strategies for Advanced Practice Providers to Increase Uptake
December 12, 2023 16:52 - 25 minutes - 23 MBIn this episode, Dr Tavell Kindall and Jona Tanguay discuss actionable strategies for advanced practice providers to increase the frequency at which PrEP is offered and initiated in primary care settings. Topics covered include: Available training resources on how to offer PrEP in primary care Affordable, accessible PrEP options, including patient assistance programs Using electronic health records to identify candidates for PrEP Opportunities to offer PrEP during appointments regarding ...
Where We Want to Be: The Search for a Cure for HIV
December 11, 2023 16:00 - 52 minutes - 48.2 MBIn this third of 3 episodes, global HIV experts and advocates discuss the current status of HIV cure research, including key concepts to understand and communicate when counselling patients, colleagues, and the broader community on HIV cure: Latest understanding of the viral reservoir New insights and questions on the best timing for cure interventions Current investigational strategies showing promise Ethical considerations related to participant education, representation in clinical t...
CRE-ating Success: How I Use Rapid Diagnostic Tests to Manage Carbapenem-Resistant Enterobacterales Bacteremia
December 07, 2023 17:57 - 15 minutes - 14.6 MBIn this podcast, Julie Ann Justo, PharmD, MS, FIDSA, BCPS, discusses treatment of carbapenem-resistant Enterobacterales (CRE) infections, including: Burden of CRE infections in the United States Mechanisms of resistance Changing epidemiology Use of rapid diagnostic tests IDSA guidance recommendations, including supporting data Approach to designing treatment regimens, including weighing patient- and infection-related factors Faculty: Julie Ann Justo, PharmD, MS, FIDSA, BCPS Clinical ...
Investigational PPAR-delta Agonist for PBC Treatment and Race-Based Considerations for PBC Diagnosis: Conference Coverage of AASLD
December 07, 2023 05:00 - 9 minutes - 8.56 MBDuring the 2023 American Association of the Study of Liver Diseases (AASLD) conference, exciting and important results from many primary biliary cholangitis (PBC) clinical trials were reported, including 3 late-breaking studies on the PPAR-delta agonist seladelpar, the dual PPAR agonist elafibranor, and the combination of the FXR agonist obeticholic acid and a fibrate. In this episode, Stuart C. Gordon, MD, FAASLD, discusses topline results from one of these late-breaking studies and more, ...
PrEP Talks: Uptake in Young Adults and Adolescents
December 07, 2023 05:00 - 19 minutes - 18.2 MBIn this episode, Errol L. Fields, MD, PhD, MPH, and Armonté Butler, MPH, a pre-exposure prophylaxis (PrEP) advocate, discuss strategies for overcoming barriers to uptake of PrEP for HIV in adolescents and young adults, based on the unique needs of this patient population. Topics covered include: Methods for building trust between patients and providers Ways to practice shared decision-making and how this process hinges on respecting patients’ autonomy and personhood How to empower young p...
Investigational Dual PPAR Agonist, FXR Agonist With Fibrate, and Hyperlipidemia in People With PBC: Conference Coverage of AASLD
December 06, 2023 19:12 - 9 minutes - 8.3 MBDuring the 2023 American Association of the Study of Liver Diseases (AASLD) conference, exciting and important results from many primary biliary cholangitis (PBC) clinical trials were reported, including 3 late-breaking studies on the PPAR-delta agonist seladelpar, the dual PPAR agonist elafibranor, and the combination of the FXR agonist obeticholic acid and a fibrate. In this episode, Marlyn J. Mayo, MD, discusses topline results from several of these studies and more, including: A phase...
Are We Making Our Patients Fight for PrEP?
December 04, 2023 21:34 - 3 minutes - 3.58 MBIn this episode, Martin Rios discusses how pre-exposure prophylaxis (PrEP) persistence depends on healthcare professional knowledge, including: Their own experiences with the various PrEP providers they have seen The relief that has come with seeing PrEP providers who are supportive and knowledgeable about the different PrEP options The challenges that have come with seeing PrEP providers who are unwilling to prescribe PrEP altogether or who will prescribe PrEP when asked but are not know...
Q&A on HIV PrEP: Episode 6 on Cisgender Women
December 04, 2023 20:59 - 35 minutes - 32.7 MBIn this episode, Meredith Clement, MD, and Whitney C. Irie, MSW, PhD, discuss key considerations for pre-exposure prophylaxis (PrEP) uptake in cisgender women, including: How to incorporate conversations on PrEP during a short clinic visit Helpful resources about PrEP to share with patients Leveraging clinic staff to improve PrEP uptake and persistence Available data on on-demand PrEP Approach to discussing PrEP contraindications and adverse events with patients Considerations for P...
The Rise of RSV: Updates on Seasonality
November 30, 2023 19:28 - 8 minutes - 7.46 MBIn this episode, Helen Y. Chu, MD, MPH, shares updates on RSV seasonality, including: Surveillance limitations due to the testing availability in adults Current 2023/2024 season trends, including predictions for other respiratory viruses (eg, influenza, SARS-CoV-2) Considerations for RSV administration RSV vaccine coadministration with influenza and COVID-19 vaccines Faculty: Helen Y. Chu, MD, MPH Associate Professor of Medicine Division of Allergy & Infectious Diseases University o...
Ready, Set, Vaccinate! RSV Vaccination for Older Adults
November 30, 2023 19:22 - 16 minutes - 14.8 MBIn this episode, Rick Zimmerman, MD, MPH, FAAFP, discusses RSV vaccines in older adults, including: Breakthroughs in RSV vaccine development RSV vaccine snapshot in older adults FDA-approved RSV vaccines for older adults CDC evidence to recommendations framework for vaccines RSV burden in older populations Benefits and harms of RSV vaccination RSV vaccine efficacy and safety in older adults CDC Advisory Committee Immunization Practices recommendations for RSV vaccines in older adult...
A Difficult Differential: Clinical Presentation and Diagnosis of RSV in Adults
November 30, 2023 19:17 - 8 minutes - 7.97 MBIn this episode, Angela Branche, MD; Pamela Rockwell, DO, FAAFP; and Richard Zimmerman, MD, MPH, FAAFP, discuss the clinical presentation of RSV in older adults and available diagnostic tests for RSV, including: Comparison of RSV clinical symptoms to influenza and COVID-19, including differentiating symptoms at infection onset RSV disease progression RSV diagnostic approaches How RSV diagnosis of adults may differ from diagnosis of children Clinical considerations for RSV testing Ho...
Q&A on HIV PrEP: Episode 4 on Adolescents and Young Adults Part 2
November 30, 2023 19:05 - 15 minutes - 14.5 MBIn this episode, Samantha V. Hill, MD, MPH, and Eunice E. Radcliff, MD, discuss key considerations for PrEP uptake in adolescents, including: Advice on talking with parents about the importance of adolescents having alone time with their healthcare professionals Maintaining confidentiality when someone is on their parents’ insurance Strategies to increase awareness, uptake, engagement, and persistence on PrEP among adolescents Having discussions about HIV prevention and PrEP along with ...
Audio Hepatitis B Update: CCO Independent Conference Coverage of AASLD 2023
November 30, 2023 18:33 - 37 minutes - 34.2 MBIn this episode, Nancy Reau, MD, discusses new data on hepatitis B virus presented at AASLD 2023, including: Current therapies Studies 108 and 110: Factors Linked With Lack of Virologic Suppression After 8 Yr of TAF or TDF Kaiser Permanente Northern California: HCC or Death With TDF vs ETV for Chronic Hepatitis B Early vs Late Postpartum Cessation of TDF Initiated for Prevention of Vertical HBV Transmission Investigational functional cure strategies B-Together: Sequential Bepirovirsen ...
Podcast on On-Demand PrEP: Strategies to Support PrEP Persistence and Reengagement
November 30, 2023 18:30 - 15 minutes - 13.9 MBIn this episode, Jean-Michel Molina, MD, PhD, discusses the data and recommendations for considering on-demand PrEP as a strategy to support PrEP persistence and engagement for men who have sex with men, including: Nondaily PrEP options recommended for cisgender men Data from the ANRS IPERGAY study evaluating on-demand FTC/TDF vs placebo in men who have sex with men Real-world data on the effectiveness of on-demand PrEP Considerations for on-demand FTC/TDF in people with renal dysfunctio...
Role of Quantitative HBsAg Testing in Clinical Practice for People With CHB
November 29, 2023 20:56 - 18 minutes - 17.1 MBShould quantitative HBsAg testing be used routinely in clinical practice for patients living with chronic hepatitis B? In this episode, Tatyana Kushner, MD, MSCE, discusses the role of quantitative hepatitis B surface antigen testing in people living with chronic hepatitis B, including: Determination of inactive carrier status Prediction of liver fibrosis/cirrhosis Prediction of hepatocellular carcinoma development Monitoring response to treatment, including future HBV treatments in the...
Which Patients With Hepatitis B Should We Be Treating?
November 29, 2023 19:58 - 20 minutes - 18.9 MBAre we treating HBV early enough? Is it time to move the goalposts regarding the timing of treatment initiation? What are the potential benefits of earlier treatment? To answer these questions, Ira M. Jacobson, MD, leads a panel discussion with Tatyana Kushner, MD, MSCE, and Paul Y. Kwo, MD, exploring which patients with HBV we should be treating, including a focus on: Guideline-based treatment recommendations and their limitations Data describing the relationship between viral suppressio...
A Hidden Annual Epidemic: The Burden of RSV in Adults
November 29, 2023 19:37 - 12 minutes - 11.1 MBIn this episode, Angela Branche, MD; Pamela Rockwell, DO, FAAFP; and Rick Zimmerman, MD, MPH, FAAFP, discuss the burden of RSV in older adults, including: RSV burden throughout life RSV seasonality in the United States Comparative burden and incidence of RSV and influenza in adults aged 65 years or older Cardiopulmonary hospitalizations of long-term care facility residents with influenza and/or RSV Risk factors for severe RSV (eg, hospitalization, mortality) in older adults RSV inciden...
Podcast on Addressing Social Determinants: Strategies to Support PrEP Persistence and Reengagement
November 28, 2023 05:00 - 15 minutes - 14.2 MBIn this episode, Beatriz Grinsztejn, MD, PhD, discusses the data and recommendations for addressing social determinants as a strategy to support PrEP persistence and engagement for transgender women, including: HIV prevalence among transgender women Data on the PrEP cascade from the PrEParadas study of daily FTC/TDF among transgender women Data from the ImPrEP Study on early loss to follow-up, adherence, long-term engagement, and HIV incidence among transgender women Barriers to PrEP up...
Trailblazers: Pharmacist’s Role in Optimizing New RSV Vaccines for Older Adults
November 27, 2023 15:30 - 19 minutes - 18.1 MBIn this accredited podcast episode, Dr Christina Madison and Dr Mary Bridgeman provide practical strategies for implementing RSV vaccination into practice, including: Educating older adults on RSV vaccines Providing effective, evidence-based recommendations Shared decision-making Identifying and addressing vaccine hesitancy Proactive strategies in vaccinating for RSV Predicting and overcoming barriers to RSV vaccination Presenters: Mary Barna Bridgeman, PharmD, BCPS, BCGP, FASCP, FC...
Light on the Horizon: Developments in RSV Vaccines
November 21, 2023 21:42 - 16 minutes - 15.4 MBIn this accredited podcast episode, Dr Christina Madison and Dr Mary Bridgeman discuss the latest practical strategies for preventing RSV infection in older adults, including: Role of basic public health precautions Available and emerging vaccines Mechanisms of action, therapeutic targets, and pharmacology Efficacy and safety data FDA approval status and ACIP recommendations Presenters: Mary Barna Bridgeman, PharmD, BCPS, BCGP, FASCP, FCCP, FNAP Clinical Professor Ernest Mario Sch...
Surveying the Landscape: Annual Burden of RSV in Older Adults
November 21, 2023 16:21 - 12 minutes - 11.8 MBIn this accredited podcast episode, Dr Mary Bridgeman discusses the most important things for pharmacists across all settings to know about RSV infections in patients 60 years of age or older, including: Incidence and prevalence of RSV in older adults, including hospitalization, mortality, epidemiology Seasonality Clinical manifestations Risk factors for severe outcomes Vulnerable groups and comorbidities Presenter: Mary Barna Bridgeman, PharmD, BCPS, BCGP, FASCP, FCCP, FNAP Clinical...
Q&A on HIV PrEP: Episode 5 on Transgender Individuals and Racial and Ethnic Minority Men Who Have Sex With Men Part 2
November 21, 2023 05:00 - 41 minutes - 38.4 MBIn this episode, Aniruddha (Anu) Hazra, MD, and Ofole Mgbako, MD, discuss key considerations for PrEP uptake in transgender individuals and racial and ethnic minority men who have sex with men, including: Data on drug–drug interactions between PrEP options and gender-affirming hormone therapy Contributing factors to inequities in PrEP uptake for Black and Latino individuals Data on FTC/TAF PrEP for transgender individuals How to decide whether to do an oral lead-in before starting injec...
NDM-Producing Enterobacterales: Applying Best Practices in Complex Clinical Scenarios
November 16, 2023 14:38 - 17 minutes - 15.7 MBIn this episode,Emily Heil, PharmD, MS, BCIDP, AAHIVP; Laila Woc-Colburn, MD; and Trevor Van Schooneveld, MD, FSHEA, FACP, discuss their approach to managing infections caused by NDM-producing Enterobacterales, including: Ambler classification of β-lactamases Mechanisms of resistance 2023 IDSA guidance recommendations The latest clinical data by antimicrobial regimen: Ceftazidime/avibactam and aztreonam Cefiderocol Investigational aztreonam/avibactam Clinical case of NDM-producing E...
DTR-Pseudomonas aeruginosa: Applying Best Practices in Complex Clinical Scenarios
November 16, 2023 14:31 - 17 minutes - 16 MBIn this episode, Emily Heil, PharmD, MS, BCIDP, AAHIVP; Laila Woc-Colburn, MD; and Trevor Van Schooneveld, MD, FSHEA, FACP, discuss their approach to managing infections involving Pseudomonas aeruginosa with difficult-to-treat resistance, including: Mechanisms of β-lactam resistance Effect of resistance mechanism on susceptibility to antipseudomonal agent 2023 IDSA guidance recommendations Activity against newer antipseudomonal β-lactams in the United States The latest clinical data b...
Carbapenem-Resistant Acinetobacter baumannii: Applying Best Practices in Complex Clinical Scenarios
November 15, 2023 19:12 - 28 minutes - 26.4 MBIn this episode, Emily Heil, PharmD, MS, BCIDP, AAHIVP; Laila Woc-Colburn, MD; and Trevor Van Schooneveld, MD, FSHEA, FACP, discuss their approach to managing infections involving carbapenem-resistant Acinetobacter baumannii (CRAB), including: Mechanisms for β-lactam resistance Additional resistance mechanisms and virulence factors 2023 IDSA guidance recommendations for moderate to severe CRAB infections The latest clinical data by antimicrobial therapy/regimen: Sulbactam Meropenem an...
Where We’re Going: The Next Wave of Antiretroviral Innovations
November 15, 2023 05:00 - 29 minutes - 26.6 MBIn this second of 3 episodes, global HIV experts and advocates discuss how HIV care can better meet the diverse needs of people living with HIV as new treatment strategies emerge and continue to evolve, including: How the emergence of long-acting injectable HIV treatment has been a game-changer for many people living with HIV Emerging strategies that are expanding the application of long-acting ART to address unmet treatment needs Potential for future innovations in ART that are hoped wil...
PrEP Today: An HIV Prevention Revolution
November 13, 2023 17:55 - 26 minutes - 24.2 MBIn this episode, global PrEP experts and advocates discuss how current PrEP regimens represent a revolutionary step forward in enabling many individuals to avoid HIV acquisition, including: How PrEP has empowered people to take control of their sexual lives, revolutionized people’s sexual experiences, and, for some, improved their experiences with healthcare in general The extraordinary progress that has been made in New South Wales and specifically in inner Sydney toward HIV transmission...
Unlocking the Promise of PrEP and the Future of PrEP
November 13, 2023 17:52 - 45 minutes - 41.9 MBIn this episode, global PrEP experts and advocates discuss barriers that have prevented the full potential of today’s PrEP regimens from being delivered, how those barriers might be overcome, and how the next generation of PrEP modalities may address unmet needs, including: How access and implementation of PrEP have limited its benefit and led to disparities in uptake among racial and ethnic groups in the United States and among key populations globally The challenges of adherence to PrEP...
Best Practices in Managing Uncomplicated UTIs in the Emergency Department
November 13, 2023 05:00 - 13 minutes - 12.7 MBIn this episode, Lilly C. Lee, MD, SM, FACEP, FAAEM, discusses the best practices in management of uUTI in the emergency department, including: Patient triage Diagnostic stewardship Interdisciplinary care Strategies to overcome treatment barriers Presenter: Lilly C. Lee, MD, SM, FACEP, FAAEM Chief of Emergency Medicine Jackson Memorial Hospital Florida Poison Information Center Roxcy Bolton Rape Treatment Center Affiliated Assistant Professor of Surgery DeWitt Daughtry Family Departmen...