![Biologic Therapy In Rheumatoid Arthritis artwork](https://is4-ssl.mzstatic.com/image/thumb/Features/v4/5f/88/96/5f8896e9-9be5-529a-af14-cc807367568a/mza_1382744875394257421.png/100x100bb.jpg)
Episode 2: Establishing the Evidence: Clinical Trials with TNF Inhibitors
Biologic Therapy In Rheumatoid Arthritis
English - August 27, 2008 11:03 - 14 minutes - 12.3 MB - ★★★★ - 4 ratingsScience Health & Fitness Medicine rheumatoid arthritis rheumatology news international biologic therapy alpha tnf schering Homepage Download Apple Podcasts Google Podcasts Overcast Castro Pocket Casts RSS feed
Previous Episode: Episode 1: TNF-Alpha: Concept to Proof of Concept
Professor Smolen discusses the evidence supporting the ability of TNF-alpha agents to result in substantial and sustained improvement in symptoms of psoriatic arthritis. Agents including infliximab and etanercept result in not only clinical improvement but also slow the radiographic progression of joint disease and damage. Further, the combination therapy of a TNF-alpha agent and
methotrexate results in highly significant improvement in arthritic symptoms and signs.