078 – Interview: The Biology of Aging & Longevity
Better Health While Aging
English - November 15, 2018 14:00 - ★★★★★ - 109 ratingsMedicine Health & Fitness Science Homepage Download Apple Podcasts Google Podcasts Overcast Castro Pocket Casts RSS feed
Dr. K talks with geroscientist John Newman, MD PhD, about aging as a biological process that can be affected by diet, metabolism, and much more. They discuss Dr. Newman's research on ketogenic diets and memory in mice, applying geroscience to treat age-related problems, and much more.
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In This Episode:
Dr. K talks with geriatrician and geroscientist John Newman, MD PhD, about the biology of aging and his research on ketogenic diets and geriatric syndromes. Dr. Newman is an assistant professor at the Buck Institute for Research on Aging and in the Division of Geriatrics at UCSF. He also works on improving the hospital care of older adults. They discuss:
How aging biology research helps us understand fundamental aging processes that affect all animals
The complex relationship between aging and disease, and what is the geroscience hypothesis
Cellular hallmarks of aging, and biomarkers to assess physiological age
How we can assess someone’s physiological age
Why biomarkers of aging aren’t as useful as functional assessments of older people
How insulin, fasting, and other aspects of metabolism are related to aging
What Dr. Newman has learned from studying ketones and aging in mice
What is known about ketogenic diets in humans
What’s been shown to improve healthspan and lifespan (in mice)
Why metformin, a diabetes drug, is a “really good drug”
Why things that slow aging in the lab may not work in humans or under real-world conditions
Related episode:
071 – Interview: How Estimating Life Expectancy Helps Older Adults Get Better Care
Related Resources:
The Newman Lab at the Buck Institute for Research on Aging
John Newman’s related research:
Ketogenic diet reduces mid-life mortality and improves memory in aging mice
Strategies and Challenges in Clinical Trials Targeting Human Aging
Skipped meals could improve memory, says Buck Institute for Research on Aging researcher
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