In this episode of the Better Edge podcast, Bradley P. Knight, MD, director, Cardiac Electrophysiology, director, Center for Heart Rhythm Disorders and the Chester C. and Deborah M. Cooley Distinguished Professor of Cardiology at Northwestern Medicine, discusses the intricacies of safely and effectively implanting LAAO devices for stroke prevention in patients with atrial fibrillation. He talks about the criteria for determining whether a LAAO device is optimal for a patient and his greatest clinical challenge as a cardiac electrophysiologist when placing this closure device.