Yvonne C. Lee, MD, of Northwestern Medicine Rheumatology, explores pain mechanisms in rheumatoid arthritis (RA). Dr. Lee is an expert on the effects of central nervous system (CNS) modulation of pain in rheumatoid arthritis. She has contributed novel insights into the role of CNS modulation of pain using novel techniques, such as quantitative sensory testing and neuroimaging. She shares her recent findings on sex differences in pain, and quantitative sensory testing in patients with RA and their clinical implications.