While Melatonin binding to the MT1 and MT2 receptors may benefit aging via suppression of oncogenic gene expression and enhancement of the SCN sleep wake cycle, receptor loss occurs with senescence.

Authentic Biochemistry

English - October 25, 2020 02:40 - 29 minutes - 27.2 MB - ★★★★★ - 10 ratings
Natural Sciences Science Homepage Download Apple Podcasts Google Podcasts Overcast Castro Pocket Casts RSS feed

Previous Episode: L-TRP is precursor to MEL and NAD ;Mel regulates Sirtuins which Perform DSB repair; NAD metabolism after SIRT activity yields PAR for SSB repair. DJGPhD 21 Oct 2020.

Next Episode: Animals have adapted behavioral responses corresponding with light and temperature events to respond to and anticipate basic bioenergetics due of heterotrophy. Authentic Biochemistry . 28/10/2020

The pharmaceutical Remelteon may be a better MT1 MT2 agonist mimetic for decreasing melatonin synthesis in the aging pineal because it fails to bind MT3 receptor which is an active quinone reductase 2 synthesizing superoxide system. Published 24 October 2020 by Authentic Biochemistry Podcast; Dr Daniel J. Guerra

---

Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support