Dr Daniel Guerra introduces a novel PCD pathway- ferroptosis- that is linked to excitotoxicity and lipid peroxidation leading to neurodegeneration. Part I

Authentic Biochemistry

English - March 25, 2019 20:44 - 26 minutes - 24.1 MB - ★★★★★ - 10 ratings
Natural Sciences Science Homepage Download Apple Podcasts Google Podcasts Overcast Castro Pocket Casts RSS feed

Previous Episode: Authentic Biochemistry #3. Dr Guerra verifies the evidence to a future biochemical prolegomena for Alzhiemer's Disease

Next Episode: Dr Guerra continues : Glutamate induced ferroptosis involves lipid peroxidation and ceramide production leading to an inflammatory response in neurodegeneration

This is the first part of a diaeventontological framing of lipid peroxidative mechanisms for CNS neurodegeneration. Dr Guerra describes recent published research (JLR 2018 .59:312pp.) and develops some of the key elements of the ferroptosis programmed cell death mechanism leading to oligodendrocyte and neuronal degeneration that will participate in a grander understanding of injury-induced and idiotypic age-associated disease in the CNS. 25 March 2019.

---

Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support