ADP- Glucokinase is essential for T lymphocyte activation and pro-inflammatory cytokine synthesis and secretion. DJGPhD. 19.3.21

Authentic Biochemistry

English - March 19, 2021 23:43 - 29 minutes - 27.3 MB - ★★★★★ - 10 ratings
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Previous Episode: The control of C flux in the liver, pancreas and CNS are coordinated: Potential Axis for Immuno Senescence X Intermediary Metabolic Regulation.Authentic Biochemistry . 15 March 2021. DJG PhD.

Next Episode: Landing on epithelial-mesenchymal transition and T lymphocyte selection to explore Senescence-Associated Cancer-like Stem Cells. DJGPhD 20.3.21

•Cytokines regulate the intensity and duration of the immune response, and they can act as growth factors or stimulants or even inhibitors of T cell amplification and differentiation.

•Cytokines are glycoproteins that are synthesized through a dolichol PP mediated pathway in the ER and are thus dependent upon prenyl lipid metabolism

Endoplasmic reticulum localized ADPGK serves glycoprotein synthesis and also functions to control glycolytic vs. aerobic bioenergetic intermediary metabolic agency in lymphocytes.

Scientific Reports volume 9, Article number: 14248 (2019)

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